Tag: encephalopathy

Did the AAP Say That Vaccines Cause Severe Brain Injury?

Bob Sears is telling folks that the American Academy of Pediatrics says severe brain injuries are caused by vaccines.

Bob Sears doesn't mention that measles is much more likely to cause severe brain injury and death, or more recent studies that counter his post.
Bob Sears doesn’t mention that measles is much more likely to cause severe brain injury and death, or more recent studies that counter his post.

Did the AAP say that?

“A causal relationship they say.”

Bob Sears

No, they didn’t.

The researchers in Pediatrics didn’t even say that…

Did the AAP Say That Vaccines Cause Severe Brain Injury?

What did they say?

“This clustering suggests that a causal relationship between measles vaccine and encephalopathy may exist as a rare complication of measles immunization.”

Weibel et al on Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program

The study was about reports to VAERS

Over 23 years, the researchers (in 1998) found reports of 48 cases of acute encephalopathy among about 75,000,000 children who were vaccinated, some clustered in the second week after they received a measles containing vaccine.

Does that mean that those measles containing vaccines caused the encephalopathy?

“In the absence of a specific test to determine vaccine causation, these 48 cases may include some nonvaccine cases representing background rates.”

Weibel et al on Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program

No, it doesn’t.

It was a signal that got some attention though.

And as it has been further investigated, there has been no evidence that measles containing vaccines cause encephalitis, at least not above 1 in a million background rates.

What does cause encephalitis?

“About 1 child out of every 1,000 who get measles will develop encephalitis (swelling of the brain) that can lead to convulsions and can leave the child deaf or with intellectual disability.”

Complications of Measles

Measles.

Measles, a life-threatening vaccine-preventable disease, causes encephalitis.

Are your kids vaccinated and protected with two doses of MMR?

More on Vaccines and Severe Brain Injury

Who Is Kenneth Stoller?

It is well known that there are doctors in California writing fake medical exemptions for kids so that they can avoid getting vaccinated and protected.

Tara Zandvliet isn't the only one writing a lot of medical exemptions for vaccines.
Tara Zandvliet isn’t the only one writing a lot of medical exemptions for vaccines.

Just who these doctors are is probabaly a bit of a mystery to a lot of people.

Who Is Kenneth Stoller?

In addition to Tara Zandvliet in San Diego, Kenneth Stoller has been writing a lot of medical exemptions for kids in California.

Did Kenneth Stoller get referrals for medical exemptions through anti-vaccine groups on Facebook?
Did Kenneth Stoller get referrals for medical exemptions through anti-vaccine groups on Facebook?

In fact, he has been writing so many that he got the attention of the City Attorney in San Francisco, who is investigating “whether the San Francisco doctor has been unlawfully providing medical exemptions that allowed parents to avoid vaccinating their children, which would put those children, their playmates, their schoolmates, and the general public at greater risk of contracting a communicable disease.”

In a response to this investigation, which includes a subpoena for his medical records, Ken Stoller admits that he “issues exemptions based on considerations not listed as CDC contraindications and precaution.”

“In conclusion, the invalid interpretation that the determination of the MTFHR variant is an acceptable reason for vaccine exemptions is not based on the precepts of replication and rigorous clinical testing. It is unfortunate that the loose application of our exploratory report has been misinterpreted and used to inappropriately justify exemption of children from medically indicated vaccines.”

David M Reif, Ph.D. on the Inappropriate Citation of Vaccine Article

Since the CDC list of contraindications and precautions is what most people consider the standard of care for a medical exemption, it is a little hard to understand what his defense will be? It isn’t the continued use of MTHFR testing, is it?

“There is no published information as of yet as to how many of the 10 measles cases in children were the wild measles strain, (i.e., unvaccinated children, versus children who contracted symptoms from the vaccine, like the 38% in the Disneyland outbreak), or how many were vaccinated and contracted wild measles due to primary vaccine failure, which may be 10% or more.”

Complaint/verified Petition to Quash an Administrative Subpoena, for Declaratory and Injunctive relief against the Subpoena and in Support of an Alternative Standard of Vaccine Exemptions Recognized Under California Law

Is he going to push the myth that kids in California have vaccine strain measles?

This is not vaccine strain measles, an idea that anti-vaccine folks continue to push to scare parents away from vaccinating and protecting their kids.
This is not vaccine strain measles, an idea that anti-vaccine folks continue to push to scare parents away from vaccinating and protecting their kids.

Although some vaccine strains were detected in 2015, they were not in people who actually had measles.

“During measles outbreaks, it is important to be able to rapidly distinguish between measles cases and vaccine reactions to avoid unnecessary outbreak response measures such as case isolation and contact investigations.”

Roy et al on Rapid Identification of Measles Virus Vaccine Genotype by Real-Time PCR

They are people with a febrile rash illness. The rash and fever is a vaccine side effect. It is not vaccine-associated measles.

And primary vaccine failure is not very common at all, which is why most cases are in those who are unvaccinated.

Kenneth Stoller on Vaccines and Autism

What else does Dr. Stoller believe?

“For many children, the enviornmental illness that we have incorrectly been calling autism, is actually an illness that has been exacerbated by too many toxic vaccines. Contrary to popular belief, there are plenty of people in governmental circles who know that certain vaccine ingredients, such as ethyl mercury, found in the perservative thimerosal, will cause neurobehavioral problems and negatively impact the health of vaccinated children.”

Kenneth Stoller

Autism as encephalopathy, biomarkers, testing urine porphyrins, chelation therapy, detoxification, hyperbaric oxygen therapy – it’s all there. And it is all the type of autism-vaccine misinformation that experts say to avoid.

Many will wonder why the medical board hasn’t paid him a visit before the City Attorney in San Francisco came calling.

Is it a surprise that Kenneth Stoller found 'valid health reasons' for them to skip their daughter's vaccines?
Is it a surprise that Kenneth Stoller found ‘valid health reasons’ for them to skip their daughter’s vaccines?

But few should have any doubt that SB 276 needs to pass.

More on Kenneth Stoller

Bob Sears on Ethan Lindenberger’s Senate Testimony

Not surprisingly, Bob Sears doesn’t seem to like that he was one of the folks who was called out by Ethan Lindenberger during his testimony before Congress.

Remember, Ethan Lindenberger was testifying at the Senate Health, Education, Labor, and Pensions Committee Hearing, Vaccines Save Lives: What Is Driving Preventable Disease Outbreaks?

Bob Sears on Ethan Lindenberger’s Senate Testimony

So what did Ethan Lindenberger have to “say” about Bob Sears?

In his written testimony that was submitted to the Senate Health, Education, Labor, and Pensions Committee, he wrote:

“…the measles outbreak was made out to be a unfounded panic created by big pharmaceutical companies and meant to push legislative agendas. Del Bigtree, a celebrity in the anti-vaccine movement, spoke with “Dr. Bob Sears.” My mom and I sat down, watching this video so she could prove her beliefs were not unfounded. In this video, Dr. Bob Sears claims that in the past 15 years there hasn’t been a single death to the measles. In contrast, 449 people have had fatal reactions to the MMR vaccine.”

Testimony of Ethan Lindenberger Student at Norwalk High school Before the Senate Health, Education, Labor, and Pensions Committee March 5th, 2019

These and many other comments didn’t make it into his oral statements.

Why not?

“Although Ethan did not include this information in his verbal testimony, it was part of his original verbal statements (which were leaked), then edited out – for obvious reasons.”

Bob Sears

The obvious reason is that each witness only had five minutes to speak, not some conspiracy as Dr. Bob seems to be implying!

And his original, written statements weren’t leaked. Like the statements of every other witness, they were posted on the Senate Committee website.

After clearing up all of that, do we still need to discuss how Dr. Bob is trying to justify any of his statements about the MMR vaccine?

Even though you can guess where this is going, let’s go ahead and do it to be complete, especially since Dr. Bob really does seem to want folks to know where “the fact” of the 459 fatal reactions to the MMR vaccine come from.

You likely already know this, but they are simply reports to VAERS. And you likely also know that “inclusion of events in VAERS data does not imply causality.” That little fact is included in a disclaimer when you search the VAERS database, which is why anti-vaccine folks created their own search tool at MedAlerts – the reference Dr. Bob uses.

A report in VAERS – a death following the MMR vaccine that was found to be caused by meningococcal meningitis.

But just because we understand that these reports aren’t proof of causality doesn’t mean that we dismiss them. No one dismisses VAERS reports as unscientific, as Bob Sears claims.

“And if you are the type of doctor, or Legislator, who likes to dismiss VAERS reports as “unscientific,” then please explain why HHS even bothers to collect the data? Spend millions of dollars collecting scientific data, then do nothing with it? Who does that? And what type of scientist ignores data? Is that what Congress had in mind when it created the VAERS system as a Federal Law?”

Bob Sears

For a guy who wrote a book about vaccines, you would think he understood the purpose of VAERS…

“VAERS is used to detect possible safety problems – called “signals” – that may be related to vaccination. If a vaccine safety signal is identified through VAERS, scientists may conduct further studies to find out if the signal represents an actual risk.”

CDC on How VAERS is Used

VAERS works.

Remember, it was using VAERS data that CDC and FDA vaccine experts quickly discovered that the first RotaShield rotavirus vaccine was associated with an increased risk of intussusception.

“In addition, the American Academy of Pediatrics warned about this in a 1998 publication in Pediatrics that confirmed 48 cases of severe or fatal encephalopathy after Measles Vaccination in the 70s and 80s: 8 children died, and the rest survived but were neurologically devastated.”

Bob Sears

What about the AAP warning about encephalopathy and the measles vaccine?

Dr. Bob is talking about a 1997 paper, Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program, which concluded that “this clustering suggests that a causal relationship between measles vaccine and encephalopathy may exist as a rare complication of measles immunization.”

“Nevertheless, with a denominator of 75,000,000 vaccinees throughout 23 years, the incidence of acute encephalopathy caused by measles vaccine in this cohort can reasonably be described as very low.”

Weibel et al on Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program

Bob left that part out, didn’t he?

Considering how many children used to die and develop measles encephalitis each year, this small risk would still seem to greatly outweigh the risk of remaining unvaccinated and at risk to get measles.

Fortunately, even that risk is something we likely don’t have to worry about!

“We did not identify any association between MMR vaccination and encephalitis, aseptic meningitis, or autism.”

Mäkelä et al on Neurologic disorders after measles-mumps-rubella vaccination.

Although encephalopathy or encephalitis is still a table injury, studies have shown it is likely not associated with getting the MMR vaccine.

“For encephalitis and aseptic meningitis, the numbers of events observed within a 3-month risk interval after vaccination were compared with the expected numbers estimated on the basis of occurrence of encephalitis and aseptic meningitis during the subsequent 3-month intervals. “

Mäkelä et al on Neurologic disorders after measles-mumps-rubella vaccination.

And then there is the 2012 IOM report, Adverse Effects of Vaccines: Evidence and Causality, which found inadequate evidence to be able to conclude that encephalitis was caused by vaccines.

“The last child to die from measles infection in the United States was back in 2003. Since then, over 100 fatal VAERS reports have been filed for the MMR vaccine. At what point would mandating this no longer be considered in the interest of the greater good? “

Bob Sears

Bob ignores those reports and ignores the fact that a woman died in 2015.

He also ignores the fact that you don’t even have to go all of the way back to 2003 to find the last child who died of measles.

  • a 17-year-old died of SSPE in 2004
  • a 1-year-old died of measles in 2005
  • an 11-year-old died of SSPE in 2005
  • an 8-year-old and a 12-year-old died of SSPE in 2006
  • a 19-year-old died of SSPE in 2007
  • a 13-year-old died of SSPE in 2008
  • a 17-year-old died of SSPE in 2011
  • an infant died of SSPE in 2012

More importantly though, he ignores that fact that the only reason that there aren’t even more measles deaths these days is because most people are vaccinated and protected! Even Bob used to understand this…

“I also warn them not to share their fears with their neighbors, because if too many people avoid the MMR, we’ll likely see the diseases increase significantly.”

Bob Sears in The Vaccine Book

Unfortunately, people shared their fears with their neighbors… And we are seeing the consequences of what happens when folks scare parents away from vaccinating and protecting their kids.

Vaccines are safe, with few risks, and are obviously necessary.

More on Bob Sears’ Response to Ethan Lindenberger’s Senate Testimony

Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?

Wait, why would anyone think that getting vaccinated would make you more likely to get a vaccine-preventable disease?

Because there is a new pertussis outbreak in California and folks don’t understand how attack rates work…

Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?

We know that the latest pertussis vaccines aren’t the greatest, having issues with waning immunity.

They don’t actually make you more likely to get pertussis though, at least not relative to being unvaccinated.

“Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

What the above quote that anti-vaccine folks are misusing is actually saying is that kids who got DTaP vaccines will be more susceptible to pertussis compared to those who got DTwP, the older version of the vaccine. That’s what the whole article is about!

It is not that they will be more suspecptible to pertussis vs someone who was unvaccinated.

Dr. I: Anti-vax folks are misinterpreting that statement, not understanding that it means relative to kids who got DTwP. They think that you are saying that it is the DTaP vaccine itself that makes it more likely that a child will get pertussis, in general. Even relative to someone who is unvaccinated. I know it shouldn’t be necessary, but can you provide a simple quote to clarify this?

JDC: You are of course correct. I was asked to write-up the talk that I have given many times in the US and in many other countries. In the talk, right at the beginning, I mention that today there is 20 fold less pertussis than there was in the pre-vaccine era and that illness in vaccine failures is much less severe that illness in unvaccinated children. I also remember how wrong they were 30 years ago R/E alleged reactions to DTwP.

And if you read his latest article, The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future, especially if you read more than the abstract, you discover that’s what he is saying.

But what about linked-epitope suppression?

In “linked-epitope suppression,” memory B cells out-compete naive B cells for access to the Bordetella epitopes because they are more numerous and their receptors exhibit a higher antigen affinity. Linked-epitope suppression applies as the immune response to novel epitopes is suppressed by the strong response to initial components if they are introduced together.

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

Basically, the DTwP vaccine included many more epitopes or targets for antibodies to bind to than the newer DTaP vaccine. That’s why it worked better. And you don’t get a good response to non-vaccine epitopes or antigens.

Still, you at least have some memory B cells and antibodies after getting the DTaP vaccine, which is why the idea that getting vaccinated makes you more susceptible to pertussis is silly. You are still protected, even if the protection isn’t perfect.

That’s why Dr. Cherry recommends that folks continue to get vaccinated and protected!

“We should be more vigilant than we have been in the past to recognize and treat pertussis in all age groups so that transmission to young infants is reduced. Most important (although not discussed in this review) is to ensure that all pregnant women receive the Tdap vaccine between 27 and 36 weeks’ gestation with each pregnancy. Also, we should consider routinely administering Tdap vaccine every 3 years to all adolescents and adults who were primed with a DTaP vaccine. This suggestion is contrary to that in the current Advisory Committee on Immunization Practices recommendations. However, from the data available, this approach could be expected to decrease the circulation of B pertussis in adolescents and adults. Also, Tdap should be administered to all adolescent and adults exposed to B pertussis during a school or other group outbreak.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

He does recommend that we work on new pertussis vaccines though.

“Future cohorts would benefit from the development and use of live vaccines and less-reactogenic DTwP vaccines.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

But why are we using a vaccine that doesn’t work as well as the previous vaccine we had?

“Despite the fact that in all but 2 of the efficacy trials the DTwP vaccines had greater efficacy than did the DTaP vaccines being studied, DTaP vaccines were licensed and used in many countries throughout the world; DTaP vaccines had replaced DTwP vaccines. The urgency to adopt DTaP vaccines was driven largely by antivaccine activist groups such as “Dissatisfied Parents Together.” During the rush to adopt DTaP vaccines and tetanus, diphtheria, acellular pertussis vaccines for adults (Tdap), much of the history relating to human pertussis was overlooked.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

But the DTwP vaccines weren’t safe, right?

“The results of a number of controlled studies between 1979 and 2004 indicated that no risk of severe neurologic disease after DTwP vaccinations existed. It was noted by myself and Shields (a pediatric neurologist) that what was being called pertussis vaccine encephalopathy was not an encephalitis-like event but, instead, the first seizure or seizures of infantile epilepsy.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

No, the cases of encephalopathy that were being reported were not caused by the DTwP vaccine. And neither did the DTwP vaccine cause SIDS, as was also reported at the time.

“Since 1997, the DTaP vaccination policy has created a cohort of people (the number of which is expanding yearly) who are more susceptible to repeated clinical illness with B pertussis infection than are DTwP-vaccinated children. There is no feasible way to make this cohort less susceptible.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

And now, after helping create the current DTaP vaccination policy, anti-vaccine folks want to scare folks away from using the vaccine. Don’t let them. Don’t skip or delay this vaccine and leave your kids susceptible to getting diphtheria, tetanus, and pertussis.

More on Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?