Tag: encephalitis

Why You Have No Business Skipping the MMR Vaccine?

Believe it or not, some folks are still pushing misinformation to scare people away from getting vaccinated and protected against measles.

The Disney outbreak was not caused by a vaccine strain!
The Disney outbreak was not caused by a vaccine strain!

Ironically, this guy talks about propaganda, manipulating parents, and media lies without saying anything that is truthful.

As I’m sure you are aware, the Disney measles outbreak was not caused by a vaccine strain.

Anti-vaccine folks frequently misinterpret the meaning of these vaccine strain cases. They are people who were recently vaccinated and develop a fever and rash. They do not have measles and are not part of the outbreak counts.
Anti-vaccine folks frequently misinterpret the meaning of these vaccine strain cases. They are people who were recently vaccinated and develop a fever and rash. They do not have measles and are not part of the outbreak counts.

The outbreak strain during the Disney outbreak was B3, which can be traced to outbreaks in Africa and the Eastern Mediterranean. Neither the Disneyland outbreak nor any outbreak has been caused by a vaccine strain of measles.

What about the idea that measles is now harmless???

Or that measles isn’t deadly is a developed country with a well-nourished population???

In response to a post praising Italy's decision to dilute their new vaccine laws, some folks thought it was funny that people were dying of measles.
Italy is a developed country with a very well-nourished population, and still, there have been at least 12 measles deaths since 2017.

Why have so many people died with measles in Europe recently if it is so harmless?

Did Chris Kirckof like his own post?
Did Chris Kirckof like his own post?

Yes, research it for yourself and you will find the complications of recent measles infections he left out, including the pregnant woman with who had a miscarriage during the 2013 measles outbreak in Brooklyn.

And the 8 SSPE deaths since 2009.

Are you wondering why he started his measles counts from 2014? It was to avoid mentioning the death of the woman in Washington in 2015.

Mostly remember that the reason we don’t see even more measles cases, measles complications, and measles deaths in the United States is simply because most people are vaccinated and protected.

Vaccines are safe, with few risks, and are obviously necessary.

More on Don’t Skip the MMR Vaccine

Bob Sears on Ethan Lindenberger’s Senate Testimony

Not surprisingly, Bob Sears doesn’t seem to like that he was one of the folks who was called out by Ethan Lindenberger during his testimony before Congress.

Remember, Ethan Lindenberger was testifying at the Senate Health, Education, Labor, and Pensions Committee Hearing, Vaccines Save Lives: What Is Driving Preventable Disease Outbreaks?

Bob Sears on Ethan Lindenberger’s Senate Testimony

So what did Ethan Lindenberger have to “say” about Bob Sears?

In his written testimony that was submitted to the Senate Health, Education, Labor, and Pensions Committee, he wrote:

“…the measles outbreak was made out to be a unfounded panic created by big pharmaceutical companies and meant to push legislative agendas. Del Bigtree, a celebrity in the anti-vaccine movement, spoke with “Dr. Bob Sears.” My mom and I sat down, watching this video so she could prove her beliefs were not unfounded. In this video, Dr. Bob Sears claims that in the past 15 years there hasn’t been a single death to the measles. In contrast, 449 people have had fatal reactions to the MMR vaccine.”

Testimony of Ethan Lindenberger Student at Norwalk High school Before the Senate Health, Education, Labor, and Pensions Committee March 5th, 2019

These and many other comments didn’t make it into his oral statements.

Why not?

“Although Ethan did not include this information in his verbal testimony, it was part of his original verbal statements (which were leaked), then edited out – for obvious reasons.”

Bob Sears

The obvious reason is that each witness only had five minutes to speak, not some conspiracy as Dr. Bob seems to be implying!

And his original, written statements weren’t leaked. Like the statements of every other witness, they were posted on the Senate Committee website.

After clearing up all of that, do we still need to discuss how Dr. Bob is trying to justify any of his statements about the MMR vaccine?

Even though you can guess where this is going, let’s go ahead and do it to be complete, especially since Dr. Bob really does seem to want folks to know where “the fact” of the 459 fatal reactions to the MMR vaccine come from.

You likely already know this, but they are simply reports to VAERS. And you likely also know that “inclusion of events in VAERS data does not imply causality.” That little fact is included in a disclaimer when you search the VAERS database, which is why anti-vaccine folks created their own search tool at MedAlerts – the reference Dr. Bob uses.

A report in VAERS – a death following the MMR vaccine that was found to be caused by meningococcal meningitis.

But just because we understand that these reports aren’t proof of causality doesn’t mean that we dismiss them. No one dismisses VAERS reports as unscientific, as Bob Sears claims.

“And if you are the type of doctor, or Legislator, who likes to dismiss VAERS reports as “unscientific,” then please explain why HHS even bothers to collect the data? Spend millions of dollars collecting scientific data, then do nothing with it? Who does that? And what type of scientist ignores data? Is that what Congress had in mind when it created the VAERS system as a Federal Law?”

Bob Sears

For a guy who wrote a book about vaccines, you would think he understood the purpose of VAERS…

“VAERS is used to detect possible safety problems – called “signals” – that may be related to vaccination. If a vaccine safety signal is identified through VAERS, scientists may conduct further studies to find out if the signal represents an actual risk.”

CDC on How VAERS is Used

VAERS works.

Remember, it was using VAERS data that CDC and FDA vaccine experts quickly discovered that the first RotaShield rotavirus vaccine was associated with an increased risk of intussusception.

“In addition, the American Academy of Pediatrics warned about this in a 1998 publication in Pediatrics that confirmed 48 cases of severe or fatal encephalopathy after Measles Vaccination in the 70s and 80s: 8 children died, and the rest survived but were neurologically devastated.”

Bob Sears

What about the AAP warning about encephalopathy and the measles vaccine?

Dr. Bob is talking about a 1997 paper, Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program, which concluded that “this clustering suggests that a causal relationship between measles vaccine and encephalopathy may exist as a rare complication of measles immunization.”

“Nevertheless, with a denominator of 75,000,000 vaccinees throughout 23 years, the incidence of acute encephalopathy caused by measles vaccine in this cohort can reasonably be described as very low.”

Weibel et al on Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program

Bob left that part out, didn’t he?

Considering how many children used to die and develop measles encephalitis each year, this small risk would still seem to greatly outweigh the risk of remaining unvaccinated and at risk to get measles.

Fortunately, even that risk is something we likely don’t have to worry about!

“We did not identify any association between MMR vaccination and encephalitis, aseptic meningitis, or autism.”

Mäkelä et al on Neurologic disorders after measles-mumps-rubella vaccination.

Although encephalopathy or encephalitis is still a table injury, studies have shown it is likely not associated with getting the MMR vaccine.

“For encephalitis and aseptic meningitis, the numbers of events observed within a 3-month risk interval after vaccination were compared with the expected numbers estimated on the basis of occurrence of encephalitis and aseptic meningitis during the subsequent 3-month intervals. “

Mäkelä et al on Neurologic disorders after measles-mumps-rubella vaccination.

And then there is the 2012 IOM report, Adverse Effects of Vaccines: Evidence and Causality, which found inadequate evidence to be able to conclude that encephalitis was caused by vaccines.

“The last child to die from measles infection in the United States was back in 2003. Since then, over 100 fatal VAERS reports have been filed for the MMR vaccine. At what point would mandating this no longer be considered in the interest of the greater good? “

Bob Sears

Bob ignores those reports and ignores the fact that a woman died in 2015.

He also ignores the fact that you don’t even have to go all of the way back to 2003 to find the last child who died of measles.

  • a 17-year-old died of SSPE in 2004
  • a 1-year-old died of measles in 2005
  • an 11-year-old died of SSPE in 2005
  • an 8-year-old and a 12-year-old died of SSPE in 2006
  • a 19-year-old died of SSPE in 2007
  • a 13-year-old died of SSPE in 2008
  • a 17-year-old died of SSPE in 2011
  • an infant died of SSPE in 2012

More importantly though, he ignores that fact that the only reason that there aren’t even more measles deaths these days is because most people are vaccinated and protected! Even Bob used to understand this…

“I also warn them not to share their fears with their neighbors, because if too many people avoid the MMR, we’ll likely see the diseases increase significantly.”

Bob Sears in The Vaccine Book

Unfortunately, people shared their fears with their neighbors… And we are seeing the consequences of what happens when folks scare parents away from vaccinating and protecting their kids.

Vaccines are safe, with few risks, and are obviously necessary.

More on Bob Sears’ Response to Ethan Lindenberger’s Senate Testimony

Is the Japanese Encephalitis Vaccine the Stupidest Vaccine Known to Man?

You probably aren’t surprised to hear that Japanese encephalitis isn’t very common in the United States.

“Travelers who go to Asia are at risk for getting Japanese encephalitis (See map). For most travelers the risk is extremely low but depends on where you are going, the time of year, your planned activities, and the length of the trip. You are at higher risk if you are traveling to rural areas, will be outside frequently, or will be traveling for a long period of time”

Japanese Encephalitis

Fortunately, if you are one of those travelers who will be at risk, a Japanese encephalitis vaccine is available.

Is the Japanese Encephalitis Vaccine the Stupidest Vaccine Known to Man?

So how many people get Japanese encephalitis in the United States?

Del Bigtree thinks that it is stupid to have a vaccine against a disease that kills up to 20,400 in the world each year.
Del Bigtree thinks that it is stupid to have a vaccine against a disease that kills up to 20,400 in the world each year.

Not many, but that doesn’t mean it isn’t important to have a Japanese encephalitis vaccine if you need it, right?

“Now correct me if I’m wrong, but no one seems to be complaining of the fact that we have two vaccines that injured have injury rates adverse events of over 100 people. Nine serious adverse events. When the disease itself has only infected 12 human beings in 24 years.

That means that both of these vaccines are six times more dangerous than the disease itself, yet no one on this panel seems to want to discuss that. I imagine that you all will pass whatever it is the Japanese encephalitis next – the stupidest vaccine known to man.

Remember 12 people infected in America – 4 million people visiting the Asia every single year – 24 years – 12 people been infected, and yet we are having this conversation. It is clear that this is a money making operation for the vaccine maker and has nothing to do with actual safety.”

Del Bigtree at the ACIP Meeting

Del’s rant was in response to the Advisory Committee on Immunization Practices discussing Japanese encephalitis vaccines…

It is clear that he doesn’t understand how any of this works, so let’s correct him, since he did ask.

First things first.

Why does he think that only 12 people have been infected with Japanese encephalitis in the United States?

“In the United States, in 25-year period following licensure of JE vaccine in 1992, 12 travel-associated cases reported (< 1 case per year)”

Review of Japanese encephalitis (JE) and JE Vaccine Work Group plans

That’s actually the data from the ACIP JE Vaccine Work Group…

Japanese encephalitis is more common in Asia, where it is endemic in 24 countries in the WHO South-East Asia and Western Pacific regions.

Still, since it isn’t on the list of National Notifiable Conditions, it is possible that a low number of cases have been reported to the CDC because few of the cases actually get reported.

It is also possible that there are few cases because folks who are high risk now get vaccinated and protected. Rates were higher in the pre-vaccine era.

But there is also the fact that most travelers are not at risk to get Japanese encephalitis, so maybe there really have only been 12 cases.

“However, given the large numbers of travelers to Asia (>5.5 million U.S. travelers entered JE-endemic countries in 2004), the low risk for JE for most travelers to Asia, and the high cost of JE-VC ($400–$500 per 2-dose primary series), providing JE vaccine to all travelers to Asia likely would not be cost-effective. In addition, for some travelers with lower risk itineraries, even a low probability of vaccine-related serious adverse events might be higher than the risk for disease. Therefore, JE vaccine should be targeted to travelers who, on the basis of their planned travel itinerary and activities, are at higher risk for disease.”

Use of Japanese Encephalitis Vaccine in Children: Recommendations of the Advisory Committee on Immunization Practices, 2013

That doesn’t mean that we shouldn’t have these vaccines or that this is all part of a money-making operation, does it?

If it was a “money-making operation,” wouldn’t the ACIP recommend the Japanese encephalitis vaccines for all travelers?

Or to make even more money, wouldn’t they just add it to the routine immunization schedule and recommended it for all children?

“Travelers to JE-endemic countries should be advised of the risks for JE disease and the importance of personal protective measures to reduce the risk for mosquito bites. For some travelers who will be in a higher-risk setting based on season, location, duration, and activities, JE vaccine can further reduce the risk for infection. JE vaccine is recommended for travelers who plan to spend a month or longer in endemic areas during the JE virus transmission season.”

Use of Japanese Encephalitis Vaccine in Children: Recommendations of the Advisory Committee on Immunization Practices, 2013

Instead, they make recommendations, even with the latest updates, that virtually guarantees a very low market for the vaccine.

But if the disease isn’t common, why have a vaccine at all?

“Although symptomatic Japanese encephalitis (JE) is rare, the case-fatality rate among those with encephalitis can be as high as 30%. Permanent neurologic or psychiatric sequelae can occur in 30%–50% of those with encephalitis.”

Japanese encephalitis

Japanese encephalitis is deadly!

There have been at least 5 deaths, including 2 children, among just 12 cases (if Del's stats are right).
There have been at least 5 Japanese encephalitis deaths, including 2 children, among just 12 cases (if Del’s stats are right).

And since the Japanese encephalitis vaccines are safe, with few risks (Del is talking about VAERS reports when he talks about vaccine injury rates), why wouldn’t you get vaccinated and protected if you were going to be at risk?

“No safety concerns to date in post-licensure surveillance.”

Review of Japanese encephalitis (JE) and JE Vaccine Work Group plans

After all, there is nothing stupid about wanting to reduce your risk of getting sick and dying.

More on Japanese Encephalitis


Show Me the Vaccine Insert!

Have you ever wondered why anti-vaccine folks always ask about vaccine inserts?

It will soon be obvious that anti-vaccine folks don't really read vaccine inserts...
It will soon be obvious that anti-vaccine folks don’t really read vaccine inserts…

Would they really be happy if we handed them the entire vaccine insert before every visit?

Would they read the entire vaccine insert?

Which part of the vaccine insert do anti-vaccine even read?
Which part of the vaccine insert do anti-vaccine folks even read?

Or would they continue to only believe the parts that they think justify their decisions to leave their kids unvaccinated, unprotected, and at risk for getting life-threatening diseases?

Show Me the Vaccine Insert!

Let’s see what’s really in these package inserts…

“Measles, mumps, and rubella are three common childhood diseases, caused by measles virus, mumps virus (paramyxoviruses), and rubella virus (togavirus), respectively, that may be associated with serious complications and/or death. For example, pneumonia and encephalitis are caused by measles. Mumps is associated with aseptic meningitis, deafness and orchitis; and rubella during pregnancy may cause congenital rubella syndrome in the infants of infected mothers”

MMR II Package Insert

Wait a second!

How can anti-vaccine folks say that measles is a mild disease if the vaccine insert says that it “may be associated with serious complications and/or death.”

Have they really read this thing?

“The impact of measles, mumps, and rubella vaccination on the natural history of each disease in the United States can be quantified by comparing the maximum number of measles, mumps, and rubella cases reported in a given year prior to vaccine use to the number of cases of each disease reported in 1995. For measles, 894,134 cases reported in 1941 compared to 288 cases reported in 1995 resulted in a 99.97% decrease in reported cases; for mumps, 152,209 cases reported in 1968 compared to 840 cases reported in 1995 resulted in a 99.45% decrease in reported cases; and for rubella, 57,686 cases reported in 1969 compared to 200 cases reported in 1995 resulted in a 99.65% decrease”

MMR II Package Insert

Full stop!

How can they say vaccines don’t work when the package insert provides these stats showing it does and goes on to say that “M-M-R II is highly immunogenic and generally well tolerated.”

“The recommended age for primary vaccination is 12 to 15 months.”

MMR II Package Insert

Why are some of these folks delaying or skipping their child’s MMR vaccine? The package insert says to give it at 12 to 15 months!

“Individuals first vaccinated at 12 months of age or older should be revaccinated prior to elementary school entry.”

MMR II Package Insert

That’s the part of the package insert that says to give a second dose before kids enter kindergarten.

“There are no reports of transmission of live attenuated measles or mumps viruses from vaccinees to susceptible contacts.”

MMR II Package Insert

And that’s the part that says they can stop talking about shedding.

Maybe we should make anti-vaccine folks read these inserts…

“The following adverse reactions are listed in decreasing order of severity, without regard to causality, within each body system category and have been reported during clinical trials, with use of the marketed vaccine, or with use of monovalent or bivalent vaccine containing measles, mumps, or rubella:”

MMR II Package Insert

Do anti-vaccine folks understand that some of the things that are listed in the adverse reactions section of the package insert haven’t actually been proven to be caused by the vaccine? They are listed “without regard to causality.”

When you see them talk about SIDS and autism and package inserts, this is what they are talking about.

What about all of the “hidden” ingredients that are listed in the package insert?

Vaccine ingredients are not hard to find.

The ingredients that are so well hidden, they are listed right in the vaccine’s insert? Where does it mention all of the toxins that anti-vaccine folks are always talking about?

“…M-M-R II is highly immunogenic and generally well tolerated.”

MMR II Package Insert

The MMR vaccine works and it is safe.

It says so in the package insert.

Vaccinate your kids.

More on Vaccine Inserts

Did a Top Cancer Scientist Suddenly Die After Getting a Yellow Fever Vaccination?

We are seeing many reports that Professor Martin Gore, an oncologist at London’s Royal Marsden Hospital for more than 35 years, died suddenly after getting a yellow fever vaccine.

Could that be true?

Could someone really die after getting a routine vaccination?

Did a Top Cancer Scientist Suddenly Die After Getting a Yellow Fever Vaccination?

Of course, it could be true.

Although vaccines are very safe, they are not 100% risk free. And tragically, they do very rarely have life-threatening side effects.

To be fair, we don’t know the full story about what happened to Prof Gore, but the media reports do say that he suffered total organ failure shortly after getting his yellow fever vaccine.

What we don’t know is how shortly after getting the vaccine or if there is any evidence for another cause for his having organ failure.

Still, although most side effects are mild, it is reported that the yellow fever vaccine, which has been available for more than 80 years, can rarely cause:

How rarely?

About 1 in 55,000 for severe allergic reactions, 1 in 125,000 for severe nervous system reactions, and 1 in 250,000 for life-threatening severe illness with organ failure.

And the risks are likely higher if you are older than age 60 years, although YEL-AND and YEL-AVD are not reported to happen with booster doses of the yellow fever vaccine.

“People aged ≥60 years may be at increased risk for serious adverse events (serious disease or, very rarely, death) following vaccination, compared with younger persons. This is particularly true if they are receiving their first yellow fever vaccination. Travelers aged ≥60 years should discuss with their healthcare provider the risks and benefits of the vaccine given their travel plans.”

Yellow Fever Frequently Asked Questions

Why would you get the yellow fever vaccine if you were older than aged 60 years and you knew there was a higher risk of severe side effects?

Yellow fever itself is a life threatening disease without a cure and a case fatality rate of up to 50%, and again, YEL-AVD is not common, occurring in about 0.4/100,000 doses.

So you would typically want to get vaccinated if you were traveling to an area where yellow fever was a risk.

“Since January 2018, 10 travel-related cases of yellow fever, including four deaths, have been reported in international travelers returning from Brazil. None of the 10 travelers had received yellow fever vaccination.”

Fatal Yellow Fever in Travelers to Brazil, 2018

In addition to outbreaks, yellow fever is still endemic in forty-seven countries in Africa and Central and South America, leading to 170,000 severe cases and 60,000 deaths in recent years, including some deaths in unvaccinated travelers returning from these areas. Did you read about these deaths in the paper?

Although it is not on the routine immunization schedule, if you are traveling somewhere and yellow fever is a risk, you should get a yellow fever vaccine.

Professor Gore’s death, at age 67, is a tragedy, no matter the cause.

That we are having to talk about it because anti-vaccine folks are using his death to push their idea that vaccines aren’t safe is unconscionable.

More on Yellow Fever Vaccine Deaths

Is AFM a Form of Transverse Myelitis?

Acute Flaccid Myelitis (AFM) is a form of acute flaccid paralysis.

“AFM can be difficult to diagnose because it shares many of the same symptoms as other neurologic diseases, like transverse myelitis and Guillain-Barre syndrome. With the help of testing and examinations, doctors can distinguish between AFM and other neurologic conditions.”

About Acute Flaccid Myelitis

AFM is not transverse myelitis, Guillain-Barre syndrome (GBS), or Acute Disseminated Encephalomyelitis (ADEM) though, although anti-vaccine folks are trying hard to make a connection.

Is AFM a Form of Transverse Myelitis?

AFM is similar to transverse myelitis, in that they both affect a person’s spinal cord, but a big difference is that TM results from “an immune-mediated inflammatory attack of a person’s spinal cord.”

“This report and others indicate that AFM represents a unique subset of acute flaccid paralysis distinct from GBS and transverse myelitis. GBS typically presents with an ascending paralysis and can be associated with facial paralysis and sensory symptoms. Children with transverse myelitis have weakness and prominent sensory loss, often manifest as a spinal sensory level. By contrast, the majority of children with AFM have focal, poliomyelitis-like spinal cord paralysis with minimal or no sensory symptoms.”

Recognition and Management of Acute Flaccid Myelitis in Children

And AFM has different symptoms from both TM and GBS.

So why try to connect AFM with TM, GBS, and ADEM? Because they think that vaccines cause TM, GBS, and ADEM.

They don’t. Just like vaccines don’t cause AFM.

There is no proof in package inserts that vaccines cause AFM.
There is no proof in package inserts that vaccines cause AFM.

But can’t you find some of these things listed in the package insert for some vaccines?

Yes, but when mentioned in a vaccine’s package insert, like for autism, SIDS, or meningitis, it is in the section where it is clear that it is “without regard to causality.”

AFM is not transverse myelitis and neither are caused by vaccines.

We will hopefully learn what is causing the latest cases of AFM soon.

More on AFM and Transverse Myelitis

Myths About Warnings and Adverse Reactions in the MMR Package Inserts

Have you heard that the MMR package insert “contains 42 paragraphs of warning and adverse reactions?”

And some of those warnings include “seizures, encephalitis, pneumonia, deafness, death and MEASLES?”

Measles? From the measles vaccine?

Myths About Warnings and Adverse Reactions in the MMR Package Inserts

Is that really in the MMR package insert?

Package inserts aren't so scary once you learn what's really in them.
Package inserts aren’t so scary once you learn what’s really in them.

Let’s see, 42 paragraphs of warning and adverse reactions???

Nope.

Anti-vaccine propaganda is not informed consent.
Anti-vaccine propaganda is not informed consent.

The Warning Section, which lists all adverse reactions and safety hazards that may occur after getting a vaccine and what you should do if they occur, actually only contains five paragraphs!

There are 23 more paragraphs in the Adverse Reactions section, but as most folks understand, this section includes clinical trials experience, postmarketing experience, and voluntary reports, so it is not always possible to establish a causal relationship to vaccination for the adverse effects listed here.

What does the MMR package insert say about seizures, encephalitis, hearing loss, and death?

“Measles is also known as rubeola. It is a serious illness. Measles virus can be passed to others if you have it. Measles can give you a high fever, cough, and a rash. The illness can last for 1 to 2 weeks. In rare cases, it can also cause an infection of the brain. This could lead to seizures, hearing loss, mental retardation, and even death.

Mumps can also be passed to others. This virus can cause fever and headache. It also makes the glands under your jaw swell and be painful. The illness often lasts for several days. Sometimes, mumps can make the testicles swell and be painful. In some cases, it can cause meningitis, which is a mild swelling of the coverings of the brain and spinal cord.

Rubella is also known as German measles. It is often a mild illness. Rubella virus can cause a mild fever swollen glands in the neck, pain and swelling in the joints, and a rash that lasts for a short time. It can be very dangerous if a pregnant woman catches it. Women who catch German measles when they are pregnant can have babies who are stillborn. Also, the babies may be blind or deaf, or have heart disease or mental retardation.”

So the package insert is telling folks to get vaccinated and protected to avoid seizures, encephalitis, and death. Why don’t anti-vaccine folks ever mention that part of the package insert?

Don’t listen to anti-vaccine propaganda about vaccine package inserts.

Learn the risk of misinformed consent and following bad advice – leaving your kids unvaccinated and unprotected.

More on Myths About Warnings and Adverse Reactions in the MMR Package Inserts