internal organ dysfunction or failure – yellow fever vaccine-associated viscerotropic disease (YEL-AVD)
About 1 in 55,000 for severe allergic reactions, 1 in 125,000 for severe nervous system reactions, and 1 in 250,000 for life-threatening severe illness with organ failure.
And the risks are likely higher if you are older than age 60 years, although YEL-AND and YEL-AVD are not reported to happen with booster doses of the yellow fever vaccine.
“People aged ≥60 years may be at increased risk for serious adverse events (serious disease or, very rarely, death) following vaccination, compared with younger persons. This is particularly true if they are receiving their first yellow fever vaccination. Travelers aged ≥60 years should discuss with their healthcare provider the risks and benefits of the vaccine given their travel plans.”
Yellow Fever Frequently Asked Questions
Why would you get the yellow fever vaccine if you were older than aged 60 years and you knew there was a higher risk of severe side effects?
Yellow fever itself is a life threatening disease without a cure and a case fatality rate of up to 50%, and again, YEL-AVD is not common, occurring in about 0.4/100,000 doses.
So you would typically want to get vaccinated if you were traveling to an area where yellow fever was a risk.
“Since January 2018, 10 travel-related cases of yellow fever, including four deaths, have been reported in international travelers returning from Brazil. None of the 10 travelers had received yellow fever vaccination.”
Fatal Yellow Fever in Travelers to Brazil, 2018
In addition to outbreaks, yellow fever is still endemic in forty-seven countries in Africa and Central and South America, leading to 170,000 severe cases and 60,000 deaths in recent years, including some deaths in unvaccinated travelers returning from these areas. Did you read about these deaths in the paper?
He is simply pointing out, and seemed a little excited, that he had anti-vaccine protesters at his studio for the first time.
But if anti-vaccine folks really feel outrage over this, why is it so selective?
Where is the outrage when the comments don’t come from someone who supports vaccines?
“I want to thank the warrior moms and dads. Those of you who have an autistic child, or a child who is otherwise damaged, you know the damage isn’t always clear-cut autism. Some times it is just some variation – your kids just not quite right.
That’s why I didn’t stand and say that I have an autistic child, because my kids, I tease them and say that they are brain damaged. Uh. Sorry son.”
I don’t remember any outrage over Paul Thomas’ comments or when Del Bigtree said “Eve is autistic, that’s right, otherwise, why would she have eaten the apple,” and made this statement on his show:
“When I go visit my grandma, why don’t I see any autistic people flapping in the corner of the room.”
But that isn’t even the worse thing Del has been recorded as saying…
“But I would think when you have a child with autism, you know, or on the spectrum, you have no reference point. You have no…
I don’t want this to sound wrong, but it’s a little bit more like having a dog or a Doberman or something that you don’t understand how it thinks, you don’t know. I mean, I mean a better figure than animal reference except… you don’t have their brain.
Or you hear about stories of people that bring home of exotic you know of chimpanzee or something where they can’t, and this is not sounding right.”
At least he didn’t want it to sound wrong…
“They get the shot. That night they have a fever of 103. They go to sleep, and three months later their brain is gone. This is a holocaust, what this is doing to our country.”
Robert F. Kennedy, Jr
The anti-vaccine world is full of talk of autistic kids being broken and damaged, they push dangerous and expensive “cures” on parents, and spread propaganda to scare parents away from vaccinating and protecting their kids.
And they hijack every disease, story, and tragedy to make folks think that everything is a vaccine injury.
As a physician, I assure you this story isn’t believable at any level. In my opinion, the “health officials” are conjuring meningitis fairy tales about an “unvaccinated” boogeyman to cover for the much more probable cause of this child’s death: VACCINES.
The much more likely cause is right in front of us: “The child had just received his 4-month-old vaccinations two days beforehand.”
Jim Meehan, for example, is so upset that he thinks Zdogg should lose his medical license, but he had no problem harassing the family of an infant who had just died of meningitis, claiming it was a cover up for a vaccine injury.
Have I mentioned that some of them lie about religious and medical exemptions to avoid getting their kids vaccinated and protected? And others sell those vaccine exemptions?
“A Clallam County woman in her 20s died this year from an undetected measles infection discovered only after an autopsy, state health officials said Thursday. The case is the first confirmed measles death in the U.S. in 12 years.
The woman was likely exposed to the highly contagious infection at a local medical center during a recent outbreak in Clallam County. She was at the site at the same time as someone who later developed a rash and was determined to be contagious for measles.”
Undetected measles led to death of Clallam County woman in her 20s
Where is the outrage when someone dies from a disease that could have easily been prevented by a safe and effective vaccine?
Those of us who understand the hypocrisy of the anti-vaccine movement know exactly where it is.
More on The Moral Outrage of the Anti-Vaccine Movement
“Chickenpox (varicella) is generally a much milder illness in children than in adults, with considerably lower rates of severe disease and death. Varicella is also virtually universal in many populations, meaning that very few individuals escape infection over a lifetime. Thus, a sound logic underlies the idea of chickenpox parties, at which susceptible children can acquire the contagious causative pathogen, varicella zoster virus (VZV), from their peers. However, chickenpox is not without risks, even for children of this age; severe, complicated, and occasionally fatal varicella occur in previously healthy children, as well as the immunocompromised (who are at very considerable risk).”
Hambleton et al on Chickenpox Party or Varicella Vaccine?
Most folks understand that. They get their kids vaccinated and have helped get chicken pox under very good control, with outbreaks of chicken pox declining over 95%.
“Each year, more than 3.5 million cases of varicella, 9,000 hospitalizations, and 100 deaths are prevented by varicella vaccination in the United States”
CDC on Monitoring the Impact of Varicella Vaccination
Apparently, not everyone has gotten the message though.
Remember when CPS had to investigate the mom who was having chicken pox parties in Plano, Texas a few years ago?
“On the page, parents post where they live and ask if anyone with a child who has the chicken pox would be willing to send saliva, infected lollipops or clothing through the mail.”
CBS 5 Investigates mail order diseases
Or when anti-vaccine folks were selling and mailing lollipops contaminated with chicken pox to folks so that they could skip the trouble of finding a chicken pox party?
And then there’s that time that a family served chicken pox contaminated punch at their chicken pox party. Oh wait, that was The Simpsons…
So what are they up to now?
More of the same…
Apparently, there are still plenty of folks looking for chicken pox parties to infect their kids.
It is easy to see a lot of cognitive biases at play in the decision to host or bring a child to a chicken pox party, including ambiguity aversion (prefer what they think are the known risks of getting the disease), bandwagoning (they think everyone else is doing it, because in their echo chambers of anti-vaccine propaganda, everyone might), and optimism bias, etc.
There is also a very poor perception of risks, as the risks from a natural chicken pox infection are far, far greater than any risk from the vaccine.
In bigger news, Facebook has groups who’s mission is “finding pox,” so that parents can get their kids sick!
How many other PoX type groups are there on Facebook?
Do they understand the consequences of having these pox parties?
Of course, an investigation from CPS, the health department, or a medical board isn’t the most serious consequence that should discourage folks from hosting or attending a chicken pox party.
Chicken pox can be a serious, even life-threatening infection. Sure, many kids just get a mild case, but others get more serious cases and have bad complications, including skin infections, encephalitis, sepsis, or stroke.
And some people do still die from chicken pox, which is supposed to be a mild, childhood illness.
“This report describes a varicella death in an unvaccinated, previously healthy adolescent aged 15 years.”
Varicella Death of an Unvaccinated, Previously Healthy Adolescent — Ohio, 2009
Fortunately, these deaths have been nearly eliminated thanks to the chicken pox vaccine.
And that’s why parents who are on a mission for “finding pox” should rethink things and switch to a mission to get their kids vaccinated and protected.
But even before the smallpox vaccine was developed by Edward Jenner in 1796, we had variolation. While we have evidence of smallpoxinfections as early as the 2nd millennium BC, the earliest use of variolation is from the 10th to 18th Century, well after the Bible was written.
“I just decided to just google what the bible says about vaccines. There’s nothing in the bible that talks about vaccines. I just want you to think about that. So if God knew in the future that he was going to create these amazing things that were going to be the best scientific advancements, like oh, my God, they’re so great, why isn’t there anything, any inkling of talk about these things called vaccinations coming into being later to save people? If that was really God’s plan and they’re so amazing, then why isn’t it in there at all? Maybe there’s a chapter where they talk about something like an injection, like this health injection, right? Like, why didn’t God talk about that if he knew that it was going to come and save the world?”
It also shouldn’t be a surprise that they do it to try and sell you stuff, like Brittney Kara’s “Awakening Reset Program.”
Or Isagenix products.
Wait, is Isagenix mentioned in the Bible?
“You can be confident that Isagenix is committed to your success by offering you the opportunity to live a healthy, clean, and lean lifestyle—and to create wealth while doing so.”
Are multi-level marketing companies?
Brittney Kara is not the first anti-vaccine person to say that God does not support vaccines and she likely won’t be the last.
“The society of the 21st century, just as many societies and cultures in the history of human civilization, use religion as an excuse for wars, discrimination, and now for vaccination refusal.”
Pelčić on Religious exception for vaccination or religious excuses for avoiding vaccination
She may be the first to say that “believing in vaccines is a mental disorder.”
“Giving children a healthy start in life, no matter where they are born or the circumstances of their birth, is the moral obligation of every one of us. It is heartbreaking to think that three million children die each year from diseases that we can prevent.”
Nelson Mandela (2002 Vaccine Conference)
And if there is a moral obligation to get vaccinated, then what does that say about those who push propaganda that scares parents away from vaccinating and protecting their kids?
Wearing a surgical mask is very common when people are sick and want to avoid spreading their germs to others. They are also commonly worn when people are healthy and are just afraid of getting sick.
Why Do Some Folks Wear a Mask During Flu Season?
Is that why you see some folks wearing masks during flu season?
Maybe, but some folks actually have to wear a mask during flu season.
Well, they have to because they decide they don’t want to get a flu vaccine, but still want to keep their job that could put others at risk if they got sick with the flu. So basically, it is unvaccinated health care personal and others who work around sick and vulnerable people who might have to wear a mask when they are at work.
Why don’t they just get vaccinated and protected against the flu?
That’s a good question…
Some other questions to consider as you think about flu vaccine mandates include:
Do unvaccinated health care workers pose a risk to others in the course of their jobs? Of course they do. Health care personal are at high risk to get the flu, since they are often around people who are sick with the flu, and are at higher risk to get the flu if they are unvaccinated.
Does wearing a mask protect anyone? – Yes, they actually do and recent studies have concluded that “surgical face masks worn by infected persons are potentially an effective means of limiting the spread of influenza.”
Does getting a flu shot prevent you from catching the flu? – Flu shots aren’t the most effective vaccine we have, but they are the best way to avoid catching the flu, being 10 to 60% effective since 2004.
Does getting a flu shot prevent you from spreading the flu to others? Yes, and several studies have shown lower rates of nosocomial cases among hospitalized patients as more health care personal get vaccinated!
Does getting a flu shot just cause you to have milder symptoms? The flu vaccine does has many benefits besides preventing the flu, but it is certainly not limited to just causing milder symptoms.
Does wearing a mask violate your HIPAA rights? No. Unless you announce it, no one knows why you are wearing a face mask. Maybe you have herpes or a cold or are just afraid of getting sick. And the Health Insurance Portability and Accountability Act only protects patients, not employees.
So why don’t all health care personal get a flu vaccine each year?
And while some people seem to be against the idea of mandates for health care workers getting flu shots, most think it is a great idea.
“I support this requirement. I think it is a good idea. Ethically, it makes total sense. First, every doctor, nurse, and HCW knows that they are supposed to put patient interests ahead of their own interests. Whatever you think about flu shots, it is good for patients that their healthcare providers are vaccinated against the flu, particularly among patients who cannot themselves be vaccinated, such as some of the elderly, babies, people with immune diseases, and people who just received transplants or are getting cancer treatment. Vaccination does not help them. They are all immunosuppressed.”
Art Caplan on The Law: Get a Flu Shot or Wear a Mask, Healthcare Workers!
In fact, most think that there is both an ethical and a legal rationale for flu vaccine mandates for health care workers.
“Doctors and other healthcare providers have an ethical obligation to make decisions and take actions that protect patients from preventable harm. 5 Many patients are highly vulnerable to flu, so choosing not to be vaccinated is choosing to do harm—a choice that has no place in healthcare.”
Doctors choosing not to be vaccinated is choosing to do harm
It is hard to imagine that some doctors and nurses not only skip getting vaccinated, putting others at risk, but then don’t even want to wear a mask.
“When I undertook the study with the current vaccine strain on my own two triple-negative children and their three playmates, also triple- negatives, I thought: “I am going to do this very carefully now,” and, like Dr. Gear, I set up certain time schedules. I said: “I am going to start to give the vaccine now.” Every time I said “I am going to start to give it” and did not give it, two to three or four days later they came down with either pharyngitis, vomiting and abdominal pain, or a little fever.
I waited for approximately six weeks for those children to stop having some sort of febrile episode. I finally gave up. It so happened that after they got the vaccine they did not have any such episode.”
Albert Sabin on Recent Studies And Field Tests With A Live Attenuated Poliovirus Vaccine
When Albert Sabin was first researching his oral polio vaccine, he understood the problem. How could he really know if any signs or symptoms that occurred after he gave someone his vaccine were really caused by the vaccine, or just a coincidence?
“However, a report later to be given by Dr. Smorodintsev will deal with approximately 7,500 children who had received the vaccine and were carefully followed, as compared with another group, in similar number, who had not, for various types of illnesses which were occurring during the period.”
Albert Sabin on Recent Studies And Field Tests With A Live Attenuated Poliovirus Vaccine
The solution? They studied kids who had not gotten his vaccine.
You can just look at the background rate of a symptom or condition, and compare the periods before and after you start using a vaccine.
For instance, consider this study from Australia about using the HPV vaccine in boys, in which they made some predictions of what would happen after introducing the HPV vaccine.
Assuming an 80% vaccination rate with three doses per person — which equates to about 480 000 boys vaccinated and a total of 1 440 000 doses administered nationally per year in the first 2 years of the program — about 2.4 episodes of Guillain-Barré syndrome would be expected to occur within 6 weeks of vaccination. In addition, about 3.9 seizures and 6.5 acute allergy presentations would be expected to occur within 1 day of vaccination, including 0.3 episodes of anaphylaxis.
Clothier et al. on Human papillomavirus vaccine in boys: background rates of potential adverse events.
Most of you will have heard the maxim “correlation does not imply causation.” Just because two variables have a statistical relationship with each other does not mean that one is responsible for the other. For instance, ice cream sales and forest fires are correlated because both occur more often in the summer heat. But there is no causation; you don’t light a patch of the Montana brush on fire when you buy a pint of Haagan-Dazs.
When correlation doesn’t equal causation, then it’s probably a coincidence. Or it’s at least caused by some other factor.
And coincidences happen all of the time.
Is It a Vaccine Injury or a Coincidence?
That something could be a coincidence is not typically want parents want to hear though, especially if their child has gotten sick.
What does it mean that something happens coincidentally?
“Most sudden cardiac deaths that remain unexplained after necropsy are probably caused by primary cardiac arrhythmias.”
Sudden death in children and adolescents
Often it just means that it is unexplained. And that it is chance alone that it occurred as the same time as something else.
“In the absence of a specific etiology for ASDs, and a tendency among parents of children with a disability to feel a strong sense of guilt, it is not surprising that parents attempt to form their own explanations for the disorder in order to cope with the diagnosis.”
Mercer et al on Parental perspectives on the causes of an autism spectrum disorder in their children
Again, when folks blame vaccines, it is often because they have nothing else to blame.
“In some fraction of the American population, however, the belief in a link remains. One reason is a coincidence of timing: children are routinely vaccinated just as parents begin to observe signs of autism. Most vaccines are administered during the first years of life, which is also a period of rapid developmental changes. Many developmental conditions, including autism, don’t become apparent until a child misses a milestone or loses an early skill, a change that in some cases can’t help but be coincident with a recent vaccination.”
Emily Willingham on The Autism-Vaccine Myth
Think that it is too big of a coincidence that some infants develop spasms shortly after their four month vaccines?
Dr. William James West first described these types of infantile spasms in the 1840s!
And the “Fifth Day Fits,” seizures that began when a newborn was five days old, was described in the 1970s, well before we began giving newborns the hepatitis B vaccine.
But SIDS was only discovered after we began vaccinating kids, right?
“But, with millions upon millions of doses given each year to infants in the first 6 months of life across industrialized countries and with sudden infant death syndrome being the most common cause of infant death among infants 1 month or older, the coincidence of SIDS following DTP vaccination just by chance will be relatively frequent. When the two events occur, with SIDS following vaccination, well-meaning and intelligent people will blame the vaccine. They seek order out of randomly occurring events.”
Jacobson et al. on A taxonomy of reasoning flaws in the anti-vaccine movement
Of course not.
Cases of SIDS have been described throughout recorded history and have been well studied to prove that they are not associated with vaccines.
“Some events after immunisation are clearly caused by the vaccine (for example, a sore arm at the injection site). However, others may happen by coincidence around the time of vaccination. It can therefore be difficult to separate those which are clearly caused by a vaccine and those that were going to happen anyway… Scientific method is then used to determine if these events are a coincidence or a result of the vaccine.
Vaccine side effects and adverse reactions
It is easy to blame a vaccine when something happens and a child was recently vaccinated. That is especially true now that anti-vaccine folks turn every story of a child’s death or disability into a vaccine injury story.
“Autism was known well before MMR vaccine became available.”
Chen et al. on Vaccine adverse events: causal or coincidental?
Blaming vaccines when it is clear that vaccines aren’t the cause doesn’t help anyone though. It scares other parents away from vaccinating and protecting their kids. And it doesn’t help parents who need support caring for a sick child or help coping with the loss of a child.
What to Know About Vaccine Injuries vs Coincidences
While all possible adverse events after getting a vaccine should be reported to VAERS and your pediatrician, remember that just because something happened after getting vaccinated, it doesn’t mean that it was caused by the vaccine.
It seems to be a big surprise to many folks, but kids can get most vaccines when they are immunosuppressed. In fact, they sometimes get extra some extra vaccines, like Pneumovax, because the “incidence or severity of some vaccine-preventable diseases is higher in persons with altered immunocompetence.”
They should also get all of their vaccines if they are around someone who is immunosuppressed.
Vaccines While Immunosuppressed
Which vaccines your kids can get while they are immunosuppressed is going to depend greatly on the reason why they are immunosuppressed.
Were they born with a specific immunodeficiency, like X-linked agammaglobulinemia, selective IgA deficiency, severe combined immunodeficiency, or chronic granulomatous disease?
Whatever the reason, they likely won’t get a medical exemption to skip all of their vaccines.
“Killed vaccines will not cause infection in immunodeficient or any other children. The fear of increased community-acquired vaccine-preventable diseases should lead to adherence to and completion of recommended immunization schedules in the community to reinforce herd immunity, such that all vaccine-preventable diseases become exceedingly rare.”
Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts
In most cases, immunocompromised kids can get all inactivated vaccines. It is only live vaccines that could pose a problem. Even then, it depends on the specific immunodeficiency as to whether avoiding live vaccines is necessary.
For example, after chemotherapy and a stem cell transplant, kids can usually get live vaccines.
Your doctors can review the latest guidelines to come up with a safe vaccination plan for your child with an immune system problem. If necessary, consultation with an infectious diseases or immunology specialist can also be helpful.
Don’t overlook other causes of possible immunosuppression when getting vaccinated, like taking daily oral steroids for more than two weeks, certain biologic immune modulators, or other medications like methotrexate, azathioprine, 6-mercaptopurine.
“Limited evidence indicates that inactivated vaccines generally have the same safety profile in immunocompromised patients as in immunocompetent individuals. However, the magnitude, breadth, and persistence of the immune response to vaccination may be reduced or absent in immunocompromised persons.”
2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host
And keep in mind that just because they can and should get vaccinated, it doesn’t mean that their vaccines are going to work as well as in someone who isn’t immunocompromised.
Vaccines for Close Contacts of Immunocompromised People
What about people who come into contacts with kids and adults who are immunocompromised?
Can they get vaccines?
“Close contacts of patients with compromised immunity should not receive live oral poliovirus vaccine because they might shed the virus and infect a patient with compromised immunity. Close contacts can receive other standard vaccines because viral shedding is unlikely and these pose little risk of infection to a subject with compromised immunity.”
Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts
Yes, close contacts can get vaccinated, especially since we don’t use the oral polio vaccine in the United States anymore.
There are some exceptions for the smallpox vaccine, which few people get, and Flumist, but only in very specific situations, including a recent hematopoietic stem cell transplant.