Tag: benefits

Why Do We Combine Vaccines?

Do you know why they combine multiple vaccines into a single shot?

Have you ever wondered why we combine vaccines? It's not a conspiracy...
It’s not a conspiracy…

Not surprisingly, your answer likely says a lot about what you think about vaccines

Why Do We Combine Vaccines?

Combination vaccines aren’t new.

The DPT vaccine was one of the first vaccines to be combined and that was way back in 1948. Before that, protection against diphtheria, tetanus, and pertussis came from three separate injections.

Want your child to get single antigen vaccines instead of a combo because you think they are getting too much in a combination vaccine? Keep in mind that the original DTP vaccine contained 3,002 antigens in each dose. And now, they get about 650 antigens from all of the vaccines they get during their whole childhood!

Which combination vaccine came next?

No, it wasn’t MMR.

How many antigens did kids get with this old schedule?

When the first polio vaccines came out, kids got three separate vaccines against the three strains of polio. They were later combined into the single polio vaccines.

And to reduce the number of injections even further, from 1959 to 1968, Quadrigen, a DTP/Polio combination was available!

And then came the MMR combination vaccine in 1971, combining protection against measles, mumps, and rubella into one shot.

Are you starting to see why we combine vaccines?

It helps reduce the number of injections that a child receives at one visit.

It has nothing to do with trying to hide any proof of a vaccine injury, after all, most parents still get their kids the same vaccines, whether or not they are combined.

Is it to save money?

In general, combination vaccines are about the same price as individual vaccines. Some are a little more and some are a little less.

It is typically easier to order, store, and administer a combination vaccine than each of the individual vaccines separately though, which can save moey. Using combination vaccines may also help to reduce errors.

Still, combining vaccines has never been about anything more than reducing the number of shots that kids have to get to be protected.

“So, at a doctor’s visit, your child may only get two or three shots to protect him from five diseases, instead of five individual shots. Fewer shots may mean less pain for your child and less stress for you.”

CDC on Combination Vaccines

Combination vaccines allow kids today to get 10 vaccines to protect them against 14 vaccine preventable diseases, but as few as 23 individual shots by age five years.

“Combination vaccines were associated with improved completion and compliance and should be encouraged among children who are undervaccinated or who received single-antigen vaccines only.”

Kurosky et al on Effect of combination vaccines on completion and compliance of childhood vaccinations in the United States

And it helps to keep vaccination rates up!

More on Combination Vaccines

Vaccines and Profiting Pediatricians

Why do some people think that pediatricians are only in it for money, working to maximize profits over the health and safety of the kids that they care for?

As they traditionally rank among the lowest paid medical doctors, even with the millions in vaccine bonuses they supposedly get, if pediatricians are only in it for the money, they are doing it wrong...
As they traditionally rank among the lowest paid medical doctors, even with the millions in vaccine bonuses they supposedly get, if pediatricians are only in it for the money, they are doing it wrong…

The usual suspects…

Vaccines and Profiting Pediatricians

Even if you believed that the average pediatrician would put profits over the health and safety of their patients, your next thought should then be why on earth would they ever vaccinate anyone…

Consider the rotavirus vaccine.

We hear a lot about the cost savings from decreased hospitalizations and ER visits because of the rotavirus vaccine.

“During the pre-rotavirus vaccine era, it was estimated that 410,000 physician visits; 205-272,000 ED visits; and 55,000–70,000 hospitalizations were attributable to rotavirus infections in U.S. children, costing approximately $1 billion annually.”

It is important to remember that for every visit to the emergency room, many more visited their pediatrician.

“National diarrhea-related healthcare visits during rotavirus season decreased by 48% (95% CI: 47%-48%) in 2008 and by 35% (95% CI: 34%-35%) in 2009 compared with the mean rate from the 2005 and 2006 rotavirus seasons.”

Yen et al on Decline in rotavirus hospitalizations and health care visits for childhood diarrhea following rotavirus vaccination in El Salvador

And now they don’t…

Pediatricians also see fewer kids with ear infections thanks to Prevnar and we rarely see a child with chickenpox.

“There was an overall downward trend in OM-related health care use from 2001 to 2011. The significant reduction in OM visit rates in 2010-2011 in children younger than 2 years coincided with the advent of PCV-13.”

Marom et al on Trends in Otitis Media–Related Health Care Use in the United States, 2001-2011

If the idea is to keep kids sick, then why vaccinate and protect them from diseases that would fill up our offices with sick kids?

“Using household-reported data we found a pattern of increased use of well visits and decreased sick visits across the last decade and half, resulting in a net decrease of roughly a third of a visit per child since 2002. The pattern was consistent for privately and publicly insured children. Multiple factors likely account for these trends, including the possibility that greater use of well visits and improvements in medicine may be helping to improve child health.”

Trends in Pediatric Well and Sick Visits, 2002-16

And contrary to the very warped idea that pediatricians vaccinate kids to promote vaccine injuries that keep kids sick, we know that propaganda about the unhealthiest generation is just that – propaganda.

More on Those Profiting Pediatricians

Is This Year’s Flu Shot Only 9% Effective?

Why do some people think that this year’s flu shot is only 9% effective?

A statement or tweet from the CDC?

The CDC has not released any information on the effectiveness of this year's flu shot yet.
The CDC has not released any information on the effectiveness of this year’s flu shot yet.

Not exactly…

Is This Year’s Flu Shot Only 9% Effective?

As the 2019-20 flu season is just getting started, we don’t actually know how effective this year’s flu vaccine will be…

She was tweeting an old story about last year's flu vaccine and the 9% number was just about one strain in the vaccine. The adjusted overall vaccine effectiveness for the 2018-19 flu vaccine was actually 47%.
Greta Van Susteren was tweeting an old story about last year’s flu vaccine and the 9% number was just about one strain in the vaccine. The adjusted overall vaccine effectiveness for the 2018-19 flu vaccine was actually 47%.

Early estimates are typically posted in mid-February.

Will we get this year’s flu vaccine effectiveness estimates early because flu season started early?

As some predicted, the circulating H3N2 strains are of a different clade than the ones in the vaccine though…

Will it help that all circulating strains are antigenically similar to the flu virus strains in this year’s flu vaccine?

Or that we are seeing more flu B this year?

During the 2017-18 flu season, the flu vaccine worked much better against flu B strains.

We don’t typically talk about flu vaccine effectiveness against flu B strains because they aren’t a big part of our flu seasons, but in general, flu vaccines work well against flu B.

“In general, current flu vaccines tend to work better against influenza B and influenza A(H1N1) viruses and offer lower protection against influenza A(H3N2) viruses.”

Vaccine Effectiveness: How Well Do the Flu Vaccines Work?

In fact, they often work better against flu B than against other strains, so maybe it will turn out to be a good thing if we see more flu B than H3N2 this year…

The flu vaccine has many benefits besides preventing you from getting the flu.
The flu vaccine has many benefits besides preventing you from getting the flu.

But most importantly, we know that the flu vaccine has many benefits and few side effects, so even when it isn’t a perfect match it makes sense to get vaccinated and protected.

And know that until we get a better, universal flu vaccine, folks should know that talk about flu vaccine effectiveness is largely academic, as a yearly flu vaccine remains the best way to protect yourself from getting the flu and developing serious complications from the flu.

More on Flu Vaccine Effectiveness

Can the Chickenpox Vaccine Cause Meningitis?

Why do some folks think that the chickenpox vaccine can cause meningitis?

Because they are misrepresenting a case report about two vaccinated teens who later developed shingles and meningitis, with a vaccine strain of chickenpox.

Can the Chickenpox Vaccine Cause Meningitis?

While that does sound like the chickenpox vaccine caused them to have meningitis, since it was a vaccine strain, it is very important to keep in mind that a natural chickenpox infection can do the exact same thing.

“Like wild-type virus, vOka can establish latency in sensory ganglia after immunization and may reactivate, leading to HZ.”

Harrington et al on Vaccine Oka Varicella Meningitis in Two Adolescents

Anyway, as can happen after a natural chickenpox infection, these two vaccinated teens developed shingles (HZ or herpes zoster).

“vOka varicella rarely results in meningitis, which is thought to occur after reactivation in a proximal dorsal root ganglion with spread to the central nervous system.”

Harrington et al on Vaccine Oka Varicella Meningitis in Two Adolescents

Unfortunately, whether the reactivation occurs after getting the chickenpox vaccine or a natural chickenpox infection, it can cause meningitis, as it did with these two teens.

So why get vaccinated?

In addition to avoiding chickenpox and its complications, getting vaccinated and protected with the chickenpox vaccine lowers your risk of later developing shingles.

“Viral meningitis accounts for approximately 26,000 to 42,000 hospitalizations each year in the United States, affecting mainly infants younger than one year, children 5–10 years of age, and the immunocompromised. Varicella Zoster virus is responsible for about 11% of those cases. Varicella can infrequently lead to Encephalitis resulting in seizures and coma (estimated 1.8 per 10,000). Other rare but serious complications of VZV include transverse myelitis, guillain-barré syndrome, thrombocytopenia, hemorrhagic varicella, purpura fulminans, glomerulonephritis, myocarditis, arthritis, and hepatitis.”

Gnoni et al on Varicella Zoster aseptic meningitis: Report of an atypical case in an immunocompetent patient treated with oral valacyclovir

And if you don’t get shingles, you shouldn’t get meningitis!

“To the best of our knowledge, these are the first cases of vOka meningitis described in adolescent patients who received 2 doses of varicella vaccine.”

Harrington et al on Vaccine Oka Varicella Meningitis in Two Adolescents

Although these teens were vaccinated, there are even more case reports of unvaccinated children and adults developing chickenpox (varicella zoster) meningitis and shingles (herpes zoster) meningitis.

That’s one of the reasons that these are life-threatening diseases that most of us try to avoid by getting vaccinated and protected!

As much as anti-vax folks are sharing this case report, it isn’t a good reason to skip or delay your child’s chickenpox vaccines. In fact, not getting vaccinated will almost certainly raise your child’s risk of developing chickenpox meningitis, from the natural strain.

More On Meningitis After the Chickenpox Vaccine