Tag: shedding

Is a Family History of Altered Immunocompetence a Contraindication to Getting Vaccinated?

Have you ever wondered why a “family history of altered immunocompetence” is listed as a contraindication to getting varicella and MMR vaccines?

If family members have altered immunocompetence, getting and exposing them to measles isn't a good idea either. — If family members have altered immunocompetence, getting and exposing them to measles isn’t a good idea either.

It’s probably not why you think…

Is a Family History of Altered Immunocompetence a Contraindication to Getting Vaccinated?

Which vaccines are contraindicated if you have a family history of altered immunocompetence?

Typically MMR and Varivax, the chicken pox vaccine.

Is this about side effects?

Kind of.

As they are live vaccines, you don’t usually want to give them to anyone who might be immunocompromised. And since some conditions that cause immune system problems can run in families, if there is a family history of these conditions, you want to make sure your child doesn’t have one before they are vaccinated.

(g) family history of congenital or hereditary immunodeficiency in first-degree relatives (e.g., parents and siblings), unless the immune competence of the potential vaccine recipient has been substantiated clinically or verified by a laboratory.

General Best Practice Guidelines for Immunization: Best Practices Guidance of the Advisory Committee on Immunization Practices (ACIP)

Fortunately, these types of severe immune problems are rare.

They might include:

Severe antibody deficiencies (e.g., X-linked agammaglobulinemia and common variable immunodeficiency)
Complete defects (e.g., SCID disease, complete DiGeorge syndrome)
Partial defects (e.g., most patients with DiGeorge syndrome, Wiskott-Aldrich syndrome, ataxia- telangiectasia)
Phagocytic deficiencies that are undefined or accompanied by defects in T-cell and NK cell dysfunction (such as a Chediak-Higashi syndrome, Leukocyte Adhesion Deficiency [LAD], and myeloperoxidase deficiency)

Talk to your pediatrician if your child has a first degree relative with one of these conditions, before they get their MMR or chicken pox vaccines.

Still, by twelve months, infants with a severe congenital or hereditary immunodeficiency or any other severe immunodeficiency will almost certainly have symptoms already.

Most children, for example, had been diagnosed with severe combined immunodeficiency (SCID), in early infancy when they have severe and life-threatening infections and failure to thrive.

And most newborns in the United States are now screened for SCID as a part of their routine newborn screening test, and can be diagnosed and treated before they have symptoms! That’s also long before they might be due for their MMR or chicken pox vaccines.

So, if your child has a family history of congenital or hereditary immunodeficiency, and it is in a first-degree relative, but has no symptoms themselves, then they can get safely vaccinated on schedule.

Not surprisingly, anti-vaccine folks try to abuse their family history of altered immunocompetence as an vaccine exemption, even when their own child isn’t immunosuppressed!

This Is the Modern Anti-Vaccine Movement

We often like to think that we know how anti-vaccine folks think.

They are just scared and trying to do the right thing for their kids, right? Just like all of the rest of us?

Maybe some of them…

This Is the Modern Anti-Vaccine Movement

Of course, you can’t group all anti-vaccine folks together, as many vaccine-hesitant or on-the-fence parents are truly just scared about the things they see and read about vaccines.

But they should know what they are getting into when they follow their favorite anti-vaccine hero, celebrity or Facebook group.

The modern anti-vaccine movement goes far deeper than worries about possible vaccine side effects.

Don’t believe me?

Hillary Simpson may not share the anti-Semitic views of one of her admins, but many of her followers do... — Hillary Simpson may not share the anti-Semitic views of one of her admins, but many of her followers do…

It is hopefully clear to everyone by now that the modern anti-vaccine movement:

exploits tragedies
exploits parents who’s children have died of vaccine-preventable diseases
exploits parents who’s children have conditions that have nothing to do with vaccines
makes dangerous recommendations, from skipping RhoGAM and vitamin K to making homemade baby formula
invokes the Holocaust as often as possible
hurts autistic people
pushes alternative treatments, including advising people to avoid getting conventional treatment for cancer!

Don’t believe me?

Why should this family have to come out and give an explanation for how their child died?

After a 4-month-old died of bacterial meningitis, anti-vaccine folks pushed the idea that it was a vaccine injury instead of an infection.

An anti-vaccine parenting group helping spread misinformation about this baby's death. — An anti-vaccine parenting group helped spread misinformation about this baby’s death.

And they push their views that everything is a vaccine injury on everyone, even though most folks understand that vaccines are not associated with SIDS, shaken baby syndrome, autism, and most other things.

There is no connection between vaccines and acute flaccid myelitis, no matter how hard anti-vaccine folks are trying to make one. — To be clear, there is no connection between vaccines and acute flaccid myelitis, no matter how hard anti-vaccine folks are trying to make one.

Award winning?

Please.

Sure, everyone and everything in anti-vaccine world is the very best, except if they are, then why are they trying so hard to convince you of that… So maybe you will agree with some of their more far-out claims, suggestions, and conspiracy theories?

Learn the risks of following bad advice. Are you really going to say no to chemotherapy if your child has cancer? — Learn the risks of following bad advice.

After all, it’s one thing to consider skipping or delaying your child’s vaccines when you think you can get away with hiding in the herd or to buy some essential oils and supplements, but are you really going to say no to chemotherapy if your child has cancer? Brandy Vaughan seems to think you should.

If there is a RISK, there must be a CHOICE.

Do you think it is okay to put infants who are too young to be vaccinated at risk for measles and other vaccine-preventable diseases because you don’t like the choices you have been given between getting your kids vaccinated and protected or keeping them out of school?

What about the parents of the kid who is being treated for cancer who gets exposed to chicken pox because someone else made the choice to not vaccinate their kid? Do you think that’s fair?

The modern anti-vaccine movement is only about choice when it is about their choices and doesn’t seem to care about the risks their unvaccinated kids pose to others.

Believe it or not, the modern anti-vaccine movement also equates getting vaccinated with rape…

Don’t believe me?

Meryl Dorey has also claimed that vaccination is rape.

Do you agree?

What else do most folks in the modern anti-vaccine movement believe?

They believe that:

vaccines don’t work, but are somehow still able to cause shedding for long periods of time
vaccines are poison and full of toxins
vaccines have no benefits and always cause injury
diseases like measles and chicken pox are good for you

And of course, they believe that vaccine advocates are behind a big conspiracy, are lying to you, and are trying to force everyone to get vaccinated.

Is that what you believe?

Some nurses and doctors are refusing to get a flu shot and have to wear masks at work.

Even though these and every other anti-vaccine point you have heard has already been refuted a thousand times already.

The RhoGAM shot helps prevent hemolytic disease of the newborn. It is not a vaccine and is not part of a Big Pharma profit ploy... — The RhoGAM shot helps prevent hemolytic disease of the newborn. It is not a vaccine and is not part of a Big Pharma profit ploy…

Do you believe in chemtrails or that Bill Gates has a plan to depopulate the world using vaccines?

“As a result, multiple breakouts of measles have occurred throughout different parts of the Western world, infecting dozens of patients and even causing deaths.”

Hussain et al on The Anti-vaccination Movement: A Regression in Modern Medicine

If you do, understand that you have been fooled by the propaganda of the modern anti-vaccine movement. If you don’t, understand that many of the folks in your anti-vaccine groups probably do.

What’s the Real Risk from the Contaminated Vaccines in India?

Most people understand that polio vaccines have helped to control and get us close to eradicating polio.

Many even know that there are two types of polio vaccine – the inactivated Salk vaccine and the live Sabin vaccine.

Some might even know that there are actually three strains of polio virus that we have traditionally gotten vaccinated against, and that one of those strains, type 2, has already been eradicated.

“In April 2016 a switch was implemented from trivalent OPV to bivalent OPV in routine immunization programmes.”

OPV Cessation

That’s why we have switched to using a bivalent OPV which only contains type 1 and 3 serotypes.

Contaminated Vaccines in India

What does all of this have to do with the news of contaminated vaccines in India?

“At least three batches of polio vaccines containing 1.5 lakh vials have been found contaminated with type 2 polio virus, putting at risk India’s “polio free” status as children born after April 2016 — when the type 2 virus was withdrawn worldwide including in India — do not have immunity to this particular virus, sources said.”

Unfortunately, some contaminated vaccines were actually administered to children in the Indian states of Maharashtra, Telengana, and Uttar Pradesh before the contamination was discovered.

Will these kids get polio?

No, as the vaccines weren’t contaminated with wild polio virus.

It seems that Bio-Med Private Limited was still producing and distributing polio vaccine with the type 2 vaccine virus, even though this type of vaccine was discontinued a few years ago.

Why?

We will hopefully find out, as the managing director of Bio-Med Pvt Ltd has been arrested, but we don’t know yet.

We do know that there is little risk from these vaccines and they won’t put India’s “polio free” status at risk.

Why would there be any risk from kids getting an extra vaccine virus strain?

It’s because the type 2 strain of polio is the most likely to cause cVDPV, or outbreaks of polio that are actually caused by the polio vaccine.

Fortunately, these outbreaks are very rare.

A dose of IPV is the backup plan to make sure a problems with the switch to bOPV doesn't end up in a tragedy. — A dose of IPV is the backup plan to make sure any problems with the switch to bOPV doesn’t end up in a tragedy.

But kids in the area are at even less at risk from these “contaminated” vaccines because as part of the plan to switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV), they likely got a dose of IPV, which includes protection against all three polio virus strains.

Not that this means that it isn’t a problem that a company was making and distributing a vaccine that kids shouldn’t have been getting.

That is terrible!

It just isn’t as big a danger as some folks are making it out to be. It is extremely unlikely that there will be any cases of polio in India, and definitely not a resurgence of polio because of these vaccines, as some have suggested.

The real risk will be that an isolated event will scare folks away from getting vaccinated and protected, even though we know that these events are rare and that vaccines are safe.

Can Flu Shots Cause the Flu?

Most folks get a flu shot each year.

Most, but not all.

Some people still think that getting a flu shot will cause them to have the flu.

Why do some people skip it?

Can Flu Shots Cause the Flu?

Yes, some people think that getting a flu shot will actually cause them to get the flu.

It’s not hard to see why though.

The flu vaccine is not the most effective vaccine we have, so it is certainly possible that you can still get sick with the flu even though you have had your flu vaccine. Of course, that’s not a good reason to skip getting a flu vaccine, as they have lots of benefits.

Some other reasons you might still think that the flu vaccine can cause the flu include that:

side effects after a flu shot can include a soreness, low-grade fever, headache and muscle aches, which some people might confuse with a mild case of the flu
many other respiratory viruses can make you sick during cold and flu season, none of which the flu vaccine protects you against
since the flu vaccine takes about two weeks to work, if you got sick shortly after being vaccinated, you may have already been exposed and developed the flu before the vaccine became effective

But why can’t the flu shot cause the flu?

That’s easy.

It’s because the flu shot is an inactivated vaccine. The influenza virus is killed or inactivated, the viral particles are purified and split up, with only the HA and NA surface glycoproteins remaining. Those glycoproteins can not cause a natural flu infection.

What about Flumist, the nasal spray flu vaccine?

While Flumist is a live virus vaccine, it is made with attenuated or weakened strains of the flu that are cold-adapted, unable to replicate at the warmer temperatures that are found in the lungs and other areas of our bodies.

So Flumist doesn’t cause the flu either.

Hopefully this is one vaccine myth that folks will stop spreading. Remember, flu vaccines don’t cause you to get sick with the flu. Get vaccinated. Flu vaccines are your best protection against the flu.

What about those folks who say that they are going to skip the flu shot because they never get sick with the flu?

They are gambling.

It is estimated that about 5 to 20% of people get the flu each year. Unless you are rarely around other people during flu season, the chances are that you will eventually get the flu, especially if you are unvaccinated and unprotected.

Can I Get Rotavirus from My Recently Vaccinated Baby?

Your two month old recently got her vaccines, including the rotavirus vaccine.

Now you have diarrhea.

Was it from shedding from your child’s rotavirus vaccine?

Does the Rotavirus Vaccine Shed?

Like some other live virus vaccines, it is well known that the rotavirus vaccine can shed.

And like with most other vaccines, this shedding isn’t usually a cause for concern and definitely isn’t a reason to think about skipping or delaying your child’s vaccines.

Why not?

“All members of the household should wash their hands after changing the diaper of an infant. This minimizes rotavirus transmission, for an undetermined number of weeks after vaccination, from an infant who received rotavirus vaccine.”

General Recommendations on Immunization Recommendations of the Advisory Committee on Immunization Practices (ACIP)

If you wash your hands when you change your child’s diapers after they have been vaccinated, just like you hopefully do anyway, you can avoid any possible contact with any rotavirus vaccine virus that might be shed in your child’s stool.

Can I Get Rotavirus from My Recently Vaccinated Baby?

But what would be the risk of your getting sick if you did come into contact with shedding rotavirus vaccine virus in your child’s diaper?

Would you be at risk to get sick?

Did your baby get sick after getting the actual vaccine?

That’s the thing about shedding that many people don’t understand. These live vaccines are made with attenuated or weakened strains of viruses, so they don’t typically get you sick when you are vaccinated. And they don’t typically get you sick when you are exposed through shedding. In fact, this shedding can sometimes help build herd immunity, as more people get exposed to the weakened strain of vaccine virus.

But can they get you sick?

Yes, if you have a problem with your immune system, which is why there are warnings about giving live vaccines to folks who are immunocompromised. And there used to be warnings about giving the oral polio vaccine to kids if they were around anyone with an immune system problem.

Vaccine viruses could also get you sick if they mutated from their attenuated state and became more virulent. Fortunately, that rarely happens with most vaccines.

“The theoretical risk of HRV and PRV shedding, transmission to, and infection of immunocompromised contacts is much lower than the real risk of wildtype rotavirus infection transmitted from unvaccinated children.”

Anderson on Rotavirus vaccines: viral shedding and risk of transmission

And most importantly, since kids are much more likely to shed virus after natural infections, it is much safer for everyone to get vaccinated and protected with these vaccines.

Surprisingly, even children with asymptomatic natural rotavirus infections can shed virus for several weeks, which is likely why these infections used to spread so easily or without known contacts.

Something that will likely surprise some folks even more is the news that just because someone gets diarrhea after being exposed to the rotavirus vaccine, either because they were vaccinated or through shedding, it doesn’t mean that the vaccine was the cause of the diarrhea!

“Of note, among all six AGE cases which possessed Rotarix-derived strains, four (sample No.1, 5, 6 and 7) were suspected to be caused by other pathogens. Most likely, the infants were infected with other pathogens during the shedding period of Rotarix strain.”

Kaneko et al on Identification of vaccine-derived rotavirus strains in children with acute gastroenteritis in Japan, 2012-2015

When vaccine strain rotavirus have been detected in kids with gastroenteritis, they often have other reasons to have diarrhea.

What does this all mean?

Don’t believe all of the hype anti-vaccine folks push about shedding from vaccines.

Does the FluMist Vaccine Shed?

Anti-vaccine folks like to talk a lot about shedding.

Where do they get the idea that vaccines shed?

Well, there is the fact that some live vaccines, like the rotavirus and oral polio vaccine, do actually shed.

Does the FluMist Vaccine Shed?

Remember, shedding occurs when an infectious agent, typically a virus, can be found in urine, stool, or other bodily secretions. Shedding is not specific to vaccines though. Shedding occurs very commonly after natural infections too, which is one reason they are so hard to control.

So does the Flumist vaccine shed?

Yes, it does, and it isn’t a secret.

There is actually a warning about shedding and Flumist – to avoid contact with severely immunosuppressed persons (e.g., hematopoietic stem cell transplant recipients in a protected enviornment) for seven days after vaccination because of the theoretical risk that their severe immunosuppression might allow the weakened flu strain to somehow cause disease.

This warning obviously doesn’t apply to the great majority of people though.

And it shouldn’t be surprising that it sheds, after all, it is a live virus vaccine that is squirted in your nose!

Why isn’t it usually a problem?

Flumist contains attenuated viral strains of the flu that are temperature-sensitive, so even if you did get infected with the weakened flu strains from Flumist via shedding, they wouldn’t cause disease.

Another way to think about it is that the folks who actually get the Flumist vaccine don’t get the flu, so why would you get the flu if you were simply exposed to the vaccine virus by shedding?

Shedding from the Flumist vaccine doesn't cause disease. — Anti-vaccine folks are sharing this table like they uncovered some secret, but it is important to understand that shedding from the Flumist vaccine doesn’t cause disease. And this table is in package insert for Flumist!

The real concern with shedding is when it leads to folks actually getting sick.

Trying to scare folks about Flumist shedding is just like when they talk about the MMR vaccine, pushing the idea that the rubella vaccine virus might shed into breast milk or measles vaccine virus into urine. Either might happen, but since it won’t cause infection and disease, it certainly isn’t a reason to skip or delay your child’s vaccines.

What to Know About Shedding and Flumist

The Flumist vaccine does indeed shed, but unless you are going to have contact with someone who is severely immunocompromised in a protected environment, this type of shedding isn’t going to get anyone sick and isn’t a reason to avoid this vaccine.

Anti-Vaxxers Should Be Able to Answer These Questions Correctly

There is a new meme going around suggesting that folks have no business telling anyone to vaccinate and protect their kids unless they can answer a series of questions.

I bet answers from anti-vaccine folks aren't the same as the answers from the rest of us... — I bet answers from anti-vaccine folks aren’t the same as the answers from the rest of us…

While it is certainly good to be educated about vaccines, their questions seem rather loaded.

Anti-Vaxxers Should Be Able to Answer These Questions Correctly

Since it is immoral and dangerous to push misinformation that scares parents away from vaccinating and protecting their kids, it would be nice if anti-vaccine folks would answer these questions before they tried to persuade anyone to not get vaccinated:

Name 5 vaccine ingredients that you think are toxic and how exactly they can be toxic at the amounts present in vaccines.
Name 5 possible complications of a vaccine-preventable disease.
Are doctors and alternative health care providers who push non-standard, parent-selected, delayed protection vaccine schedules able to be held liable if their intentionally unvaccinated child suffers a vaccine-preventable disease or starts an outbreak, infecting other people?
How many children died of vaccine-preventable diseases in the early 1980s, before the vaccine schedule grew to include the new vaccines we give today?
Is it true that no one can force you to get vaccinated?
What percentage of reports to VAERS are actually caused by vaccine reactions?
How many doses of vaccines have been given since the Vaccine Court began paying for vaccine injury cases?
Which vaccines must be avoided because of shedding or other concerns if you have a child with an immunodeficiency in your home?
Why do some folks think that many vaccines still contain thimerosal?
If today’s vaccines already contain far fewer antigens than they did in the old days, what would be the extra benefit of splitting them up even further into separate shots for each vaccine-preventable disease?
Have you read all of studies on the safety and effectiveness of combination vaccines, including those that are double-blinded and placebo controlled, and the current vaccine schedule?
Can you give me one other interesting fact about vaccines or vaccine-preventable diseases that was not already asked or discussed?

What’s my interesting fact?

Many on-the-fence and vaccine hesitant parents do change their mind about vaccines and decide to make the right choice and get their kids vaccinated and protected.

VAXOPEDIA

Is a Family History of Altered Immunocompetence a Contraindication to Getting Vaccinated?

Is a Family History of Altered Immunocompetence a Contraindication to Getting Vaccinated?

More on Vaccine Contraindications