Tag: history of the anti-vaccine movement

Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?

Wait, why would anyone think that getting vaccinated would make you more likely to get a vaccine-preventable disease?

Because there is a new pertussis outbreak in California and folks don’t understand how attack rates work…

Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?

We know that the latest pertussis vaccines aren’t the greatest, having issues with waning immunity.

They don’t actually make you more likely to get pertussis though, at least not relative to being unvaccinated.

“Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

What the above quote that anti-vaccine folks are misusing is actually saying is that kids who got DTaP vaccines will be more susceptible to pertussis compared to those who got DTwP, the older version of the vaccine. That’s what the whole article is about!

It is not that they will be more suspecptible to pertussis vs someone who was unvaccinated.

Dr. I: Anti-vax folks are misinterpreting that statement, not understanding that it means relative to kids who got DTwP. They think that you are saying that it is the DTaP vaccine itself that makes it more likely that a child will get pertussis, in general. Even relative to someone who is unvaccinated. I know it shouldn’t be necessary, but can you provide a simple quote to clarify this?

JDC: You are of course correct. I was asked to write-up the talk that I have given many times in the US and in many other countries. In the talk, right at the beginning, I mention that today there is 20 fold less pertussis than there was in the pre-vaccine era and that illness in vaccine failures is much less severe that illness in unvaccinated children. I also remember how wrong they were 30 years ago R/E alleged reactions to DTwP.

And if you read his latest article, The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future, especially if you read more than the abstract, you discover that’s what he is saying.

But what about linked-epitope suppression?

In “linked-epitope suppression,” memory B cells out-compete naive B cells for access to the Bordetella epitopes because they are more numerous and their receptors exhibit a higher antigen affinity. Linked-epitope suppression applies as the immune response to novel epitopes is suppressed by the strong response to initial components if they are introduced together.

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

Basically, the DTwP vaccine included many more epitopes or targets for antibodies to bind to than the newer DTaP vaccine. That’s why it worked better. And you don’t get a good response to non-vaccine epitopes or antigens.

Still, you at least have some memory B cells and antibodies after getting the DTaP vaccine, which is why the idea that getting vaccinated makes you more susceptible to pertussis is silly. You are still protected, even if the protection isn’t perfect.

That’s why Dr. Cherry recommends that folks continue to get vaccinated and protected!

“We should be more vigilant than we have been in the past to recognize and treat pertussis in all age groups so that transmission to young infants is reduced. Most important (although not discussed in this review) is to ensure that all pregnant women receive the Tdap vaccine between 27 and 36 weeks’ gestation with each pregnancy. Also, we should consider routinely administering Tdap vaccine every 3 years to all adolescents and adults who were primed with a DTaP vaccine. This suggestion is contrary to that in the current Advisory Committee on Immunization Practices recommendations. However, from the data available, this approach could be expected to decrease the circulation of B pertussis in adolescents and adults. Also, Tdap should be administered to all adolescent and adults exposed to B pertussis during a school or other group outbreak.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

He does recommend that we work on new pertussis vaccines though.

“Future cohorts would benefit from the development and use of live vaccines and less-reactogenic DTwP vaccines.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

But why are we using a vaccine that doesn’t work as well as the previous vaccine we had?

“Despite the fact that in all but 2 of the efficacy trials the DTwP vaccines had greater efficacy than did the DTaP vaccines being studied, DTaP vaccines were licensed and used in many countries throughout the world; DTaP vaccines had replaced DTwP vaccines. The urgency to adopt DTaP vaccines was driven largely by antivaccine activist groups such as “Dissatisfied Parents Together.” During the rush to adopt DTaP vaccines and tetanus, diphtheria, acellular pertussis vaccines for adults (Tdap), much of the history relating to human pertussis was overlooked.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

But the DTwP vaccines weren’t safe, right?

“The results of a number of controlled studies between 1979 and 2004 indicated that no risk of severe neurologic disease after DTwP vaccinations existed. It was noted by myself and Shields (a pediatric neurologist) that what was being called pertussis vaccine encephalopathy was not an encephalitis-like event but, instead, the first seizure or seizures of infantile epilepsy.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

No, the cases of encephalopathy that were being reported were not caused by the DTwP vaccine. And neither did the DTwP vaccine cause SIDS, as was also reported at the time.

“Since 1997, the DTaP vaccination policy has created a cohort of people (the number of which is expanding yearly) who are more susceptible to repeated clinical illness with B pertussis infection than are DTwP-vaccinated children. There is no feasible way to make this cohort less susceptible.”

JD Cherry on The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future

And now, after helping create the current DTaP vaccination policy, anti-vaccine folks want to scare folks away from using the vaccine. Don’t let them. Don’t skip or delay this vaccine and leave your kids susceptible to getting diphtheria, tetanus, and pertussis.

More on Does Getting the DTaP Vaccine Make You More Susceptible to Pertussis?

This Is the Modern Anti-Vaccine Movement

We often like to think that we know how anti-vaccine folks think.

They are just scared and trying to do the right thing for their kids, right? Just like all of the rest of us?

Maybe some of them…

This Is the Modern Anti-Vaccine Movement

Of course, you can’t group all anti-vaccine folks together, as many vaccine-hesitant or on-the-fence parents are truly just scared about the things they see and read about vaccines.

But they should know what they are getting into when they follow their favorite anti-vaccine hero, celebrity or Facebook group.

The modern anti-vaccine movement goes far deeper than worries about possible vaccine side effects.

Don’t believe me?

Hillary Simpson may not share the anti-Semitic views of one of her admins, but many of her followers do...
Hillary Simpson may not share the anti-Semitic views of one of her admins, but many of her followers do…

It is hopefully clear to everyone by now that the modern anti-vaccine movement:

Don’t believe me?

Why should this family have to come out and give an explanation for how their child died?
Why should this family have to come out and give an explanation for how their child died?

After a 4-month-old died of bacterial meningitis, anti-vaccine folks pushed the idea that it was a vaccine injury instead of an infection.

An anti-vaccine parenting group helping spread misinformation about this baby's death.
An anti-vaccine parenting group helped spread misinformation about this baby’s death.

And they push their views that everything is a vaccine injury on everyone, even though most folks understand that vaccines are not associated with SIDS, shaken baby syndrome, autism, and most other things.

There is no connection between vaccines and acute flaccid myelitis, no matter how hard anti-vaccine folks are trying to make one.
To be clear, there is no connection between vaccines and acute flaccid myelitis, no matter how hard anti-vaccine folks are trying to make one.

Award winning?

Please.

Sure, everyone and everything in anti-vaccine world is the very best, except if they are, then why are they trying so hard to convince you of that… So maybe you will agree with some of their more far-out claims, suggestions, and conspiracy theories?

Learn the risks of following bad advice. Are you really going to say no to chemotherapy if your child has cancer?
Learn the risks of following bad advice.

After all, it’s one thing to consider skipping or delaying your child’s vaccines when you think you can get away with hiding in the herd or to buy some essential oils and supplements, but are you really going to say no to chemotherapy if your child has cancer? Brandy Vaughan seems to think you should.

If there is a RISK, there must be a CHOICE.

Do you think it is okay to put infants who are too young to be vaccinated at risk for measles and other vaccine-preventable diseases because you don’t like the choices you have been given between getting your kids vaccinated and protected or keeping them out of school?

What about the parents of the kid who is being treated for cancer who gets exposed to chicken pox because someone else made the choice to not vaccinate their kid? Do you think that’s fair?

The modern anti-vaccine movement is only about choice when it is about their choices and doesn’t seem to care about the risks their unvaccinated kids pose to others.

Believe it or not, the modern anti-vaccine movement also equates getting vaccinated with rape…

Don’t believe me?

Meryl Dorey has also claimed that vaccination is rape.
Meryl Dorey has also claimed that vaccination is rape.

Do you agree?

What else do most folks in the modern anti-vaccine movement believe?

They believe that:

And of course, they believe that vaccine advocates are behind a big conspiracy, are lying to you, and are trying to force everyone to get vaccinated.

Is that what you believe?

Some nurses and doctors are refusing to get a flu shot and have to wear masks at work.
Some nurses and doctors are refusing to get a flu shot and have to wear masks at work.

Even though these and every other anti-vaccine point you have heard has already been refuted a thousand times already.

The RhoGAM shot helps prevent hemolytic disease of the newborn. It is not a vaccine and is not part of a Big Pharma profit ploy...
The RhoGAM shot helps prevent hemolytic disease of the newborn. It is not a vaccine and is not part of a Big Pharma profit ploy…

Do you believe in chemtrails or that Bill Gates has a plan to depopulate the world using vaccines?

“As a result, multiple breakouts of measles have occurred throughout different parts of the Western world, infecting dozens of patients and even causing deaths.”

Hussain et al on The Anti-vaccination Movement: A Regression in Modern Medicine

If you do, understand that you have been fooled by the propaganda of the modern anti-vaccine movement. If you don’t, understand that many of the folks in your anti-vaccine groups probably do.

More on the Modern Anti-Vaccine Movement

Vaccinated vs Unvaccinated – Smallpox Edition

Anti-vaccine folks really like comparing vaccinated and unvaccinated kids.

Why?

They think that unvaccinated kids are healthier, even though we know that they aren’t, they simply get more vaccine-preventable diseases.

Vaccinated vs Unvaccinated – Smallpox Edition

And we have known it for a long time. In Leicester, for example, it was known that folks weren’t vaccinated were much more likely to die of smallpox than those who were. In fact, the fatality rate in Leicester in the late 19th century and early 20th century was 1 to 2% for those who were vaccinated. What was it for folks who were unvaccinated? It was 8 to 12%!

And like many other diseases, if they did get sick, those who were vaccinated against smallpox often got a very mild case, especially as compared to those who were unvaccinated. We can see that even now thanks to photographs taken by Dr. Allan Warner, the Resident Medical Officer to the Isolation Hospital in Leicester.

Vaccinated vs unvaccinated with smallpox.

Dr. Warner’s photos have been published time and again, but they can originally be found in the New Sydenham Society’s Atlas of 1904.

Vaccinated vs unvaccinated sisters with smallpox.

There are many photos and many stories from the time that were testament to the fact that vaccines work.

“A boy, aged 14 years, unvaccinated, sickened with small pox on April 14th. He was removed to hospital on April 18th, where he had a severe confluent attack. The father consented to his wife and three children being vaccinated, stating that personally he would not be vaccinated, but would be a “test,” to see if there was anything in it.

Ten days later his daughter, aged three years, developed a small-pox eruption she had less than one hundred spots and never appeared ill. No other person in the house suffered from small-pox except the father, vaccinated in infancy, his eruption appearing fourteen days after the son had been removed to hospital. A photograph of the father and daughter, taken on the twelfth day of the father’s eruption, may be seen in Plate VI. [see below] and requires no comment.”

This father was the only one in the family who skipped getting vaccinated, and he got smallpox.
This father was the only one in the family who skipped getting vaccinated, and he got smallpox.

And there are also stories of folks skipping vaccines already. Remember, the anti-vaccine movement is even older than the first vaccines. It started with variolation. By the time these photos were taken, anti-vaccine folks had already marched on Leicester. A march that didn’t turn folks away from getting vaccinated.

The Vaccination of Contacts part of the Leicester Method is usually left out by anti-vaccination folks.
Folks were still getting vaccinated using the Leicester Method in Leicester.

For those who think getting smallpox was all about poor nutrition and hygiene, how do you explain these photos? Why such different outcomes for people in the same family, if it wasn’t their vaccine?

The smallpox vaccine clearly worked.
It was the vaccine, as this report on an outbreak of smallpox in 1903 clearly showed.

And that’s why the anti-vaccine movement “slowly faded from view” in the early 20th century.

Too bad we let them come back…

What to Know About Vaccinated vs Unvaccinated with Smallpox

It should be clear that in the era of smallpox, like with other vaccine-preventable diseases, you clearly wanted to be vaccinated.

More on Vaccinated vs Unvaccinated with Smallpox

What Are the Demands and Goals of the Anti-Vaccine Movement?

So what exactly do anti-vaccine folks want?

What are they trying to do?

Are they trying to scare parents away from getting vaccinating and protecting their kids, hoping to drag us back to the pre-vaccine era?

What Are the Demands and Goals of the Anti-Vaccine Movement?

Of course, some of the folks who are anti-vaccine don’t actually like to be called anti-vaccine. Instead, they prefer to say that they are pro-safe vaccines. So for them, it is rather obvious – they want safer vaccines without toxins.

Now, since vaccines are already safe and don’t contain any toxic ingredients, it would seem like their work is done already, right?

Another goal is having fewer vaccines on the immunization schedule. Jenny McCarthy often pushes the Turn Back the Clock immunization plan, wanting kids to only get vaccines that were on the 1983 immunization schedule, back when kids still died of meningitis, pneumonia, blood infections, severe dehydration, epiglottitis, and cancer from Hib, pneumococcal disease, rotavirus, hepatitis B, hepatitis A, chicken pox, HPV, and meningococcal disease, which are now vaccine preventable.

Other members of the anti-vaccine movement talk about vaccine choice. They want to be able to choose whether or not they should have to vaccinate their kids.

Again, done. No one is forcing parents to vaccinate their kids. We may not have a choice on whether or not your unvaccinated child gets sick and puts someone else at risk for getting a vaccine-preventable disease because they were too young to be vaccinated, had a medical exemption, or their vaccine didn’t work, but you can certainly make the choice to skip or delay any vaccines you want.

“I also warn them not to share their fears with their neighbors, because if too many people avoid the MMR, we’ll likely see the diseases increase significantly.”

Dr. Bob Sears in The Vaccine Book

What are other goals of the anti-vaccine movement?

Johns Hopkins Medicine, which includes the Johns Hopkins University School of Medicine and the The Johns Hopkins Hospital and Health System went out of their way to correct this anti-vaccine misinformation.
Johns Hopkins Medicine went out of their way to correct this anti-vaccine misinformation about shedding.

Have you heard about the anti-vaccine folks who want to quarantine all kids who have recently been vaccinated for at least six weeks? Why quarantine kids who have been vaccinated? They are worried about shedding

Would anyone go so far as wanting to ban vaccinations? Yup. So much for vaccine choice.

Some others want to rescind the 1986 National Childhood Vaccine Injury Act, which they think will help make it easier to sue vaccine manufacturers. That’s one of Andrew Wakefield‘s demands in his movie VAXXED. He and others never mention that if you are suing in civil court, then you must meet a higher burden of proof for vaccine injury than you do in Vaccine Court.

Remember when Robert F. Kennedy, Jr. thought he would be appointed to some special Trump commission on vaccines?

“We want safe vaccines, robust transparent science and an honest and independent regulatory agency focused narrowly on public health rather than industry profit.”

Robert F. Kennedy, Jr. on Mercury, Vaccines and the CDC’s Worst Nightmare

Kennedy’s vaccine commission never happened, but that hasn’t stopped him from pushing for an independent regulatory agency.

I’m not sure who would run or be a part of Kennedy’s independent regulatory agency though, as he believes that “Congress, the regulatory agencies, FDA and CDC, the IOM, the NIH, the AAP, the science journals, the university science departments and the press” have all been compromised by Pharma.

Kennedy also wants thimerosal out of vaccines, which, as most people know, is already out of all vaccines on the immunization schedule, including about 100 million doses of flu shots this past year. But like others, he seems to be moving on to aluminum as his new target.

What else?

Fortunately, it is easy to see why the demands and goals of the modern anti-vaccine movement are dangerous, unethical, and unnecessary, and like parents who decide to skip or delay vaccines, will simply put us all at risk for more outbreaks of vaccine-preventable disease.

What to Know About the Demands and Goals of the Anti-Vaccine Movement

Whatever their demands and goals of the anti-vaccine movement, the effect is that they are scaring parents away from vaccinating and protecting their kids from life-threatening vaccine-preventable diseases for no good reason.

More on the Demands and Goals of the Anti-Vaccine Movement