Tag: wild strains

Why You Have No Business Skipping the MMR Vaccine?

Believe it or not, some folks are still pushing misinformation to scare people away from getting vaccinated and protected against measles.

The Disney outbreak was not caused by a vaccine strain!
The Disney outbreak was not caused by a vaccine strain!

Ironically, this guy talks about propaganda, manipulating parents, and media lies without saying anything that is truthful.

As I’m sure you are aware, the Disney measles outbreak was not caused by a vaccine strain.

Anti-vaccine folks frequently misinterpret the meaning of these vaccine strain cases. They are people who were recently vaccinated and develop a fever and rash. They do not have measles and are not part of the outbreak counts.
Anti-vaccine folks frequently misinterpret the meaning of these vaccine strain cases. They are people who were recently vaccinated and develop a fever and rash. They do not have measles and are not part of the outbreak counts.

The outbreak strain during the Disney outbreak was B3, which can be traced to outbreaks in Africa and the Eastern Mediterranean. Neither the Disneyland outbreak nor any outbreak has been caused by a vaccine strain of measles.

What about the idea that measles is now harmless???

Or that measles isn’t deadly is a developed country with a well-nourished population???

In response to a post praising Italy's decision to dilute their new vaccine laws, some folks thought it was funny that people were dying of measles.
Italy is a developed country with a very well-nourished population, and still, there have been at least 12 measles deaths since 2017.

Why have so many people died with measles in Europe recently if it is so harmless?

Did Chris Kirckof like his own post?
Did Chris Kirckof like his own post?

Yes, research it for yourself and you will find the complications of recent measles infections he left out, including the pregnant woman with who had a miscarriage during the 2013 measles outbreak in Brooklyn.

And the 8 SSPE deaths since 2009.

Are you wondering why he started his measles counts from 2014? It was to avoid mentioning the death of the woman in Washington in 2015.

Mostly remember that the reason we don’t see even more measles cases, measles complications, and measles deaths in the United States is simply because most people are vaccinated and protected.

Vaccines are safe, with few risks, and are obviously necessary.

More on Don’t Skip the MMR Vaccine

Did New York Declare Medical Martial Law over a Measles Outbreak?

You have to admire anti-vaccine folks for one thing, they are consistent.

Well, actually, no.

Admire is the wrong word…

Did New York Declare Medical Martial Law over a Measles Outbreak?

As most folks know, Rockland County Executive Ed Day made an emergency declaration banning unvaccinated kids from public places.

I guess because he was anticipating a freak-out from anti-vaccine folks, he went out of his way to say that the emergency declaration does not mean that law enforcement will be asking for vaccine records and that they are just trying to get the attention of parents, some of whom weren’t cooperating when their kids were sick.

So what was the reaction?

About as you would expect…

Martial law?

Medical martial law? An emergency declaration saying you will get a class B misdemeanor if your unvaccinated kid goes to the mall is the same thing as martial law? Ordinary laws have been suspended and the military is taking over?

If you listened to the press conference, the problem isn’t really that we need new laws, it is that some folks aren’t cooperating with existing ones. Again, in the middle of the longest outbreak in recent history, some parents who have kids sick with measles aren’t talking to health department officials who simply want to control and stop the outbreak.

What else is wrong with the Natural News post?

Of course, it is the stuff about shedding and “improperly weakened viral strains.”

In truth, measles outbreaks are started when unvaccinated folks travel out of the country, get measles, and bring it back to a community with a lot of other unvaccinated people. And tragically, sometimes folks who are too young to be vaccinated or who have true medical contraindications to getting vaccinated get caught up in these outbreaks.

Did they listen to the press conference? When did he say that they would be going door-to-door?

Hillary Simpson telling folks in New York to riot.

Is it actually legal to tell folks to riot and incite them to open civil disobedience?

Kate Tietje calling for open civil disobedience.

Surpriginsly, most went to straight to comments about Hitler and concentration camps.

It is offensive to compare the emergency declaration in Rockland county to putting people in concentration camps.
It is offensive to compare the emergency declaration in Rockland county to putting people in concentration camps.

This is the modern anti-vaccine movement.

These are the leaders and heroes of the anti-vaccine movement.

Larry Cook on the emergency ban in Rockland County.

To be clear, rabbis in the community have been telling folks to get vaccinated and protected!

“Whoever isn’t vaccinated is a murderer” reads a rabbinic letter recently signed by leading charedi rabbis in Israel, according to Yeshiva World News. The kol koreh was distributed after a spread of Measles in the ultra-Orthodox communities in Israel and around the world. Earlier this month an unvaccinated infant died, and more than 1300 people have been infected with a preventable disease. The Gedolim who signed the Kol Koreh include: Rav Yitzchak Silberstein, Rav Shimon Ba’adani, Rav Sriel Rosenberg, Rav Moshe Shaul Klein Rav Menachem Mendel Lubin.

As Measles Spread, Leading Charedi Rabbis Come Out Strongly Against Anti-Vaxxers

I wonder what the people in these communities would think of all of this holocaust imagery that anti-vaccine folks are using to try and keep the outbreaks going?

The National Vaccine Information Center is exploiting a photo of five year old Avram Rosenthal and his two year old brother Emanuel of the Kovno ghetto in Lithuania. Both boys were later deported to the death camp at Majdanek where they were murdered.
This is a photo of five year old Avram Rosenthal and his two year old brother Emanuel of the Kovno ghetto in Lithuania. Both boys were later deported to the death camp at Majdanek where they were murdered. Why is it being used in an article about measles outbreaks?

It is very clear that this is not about religion.

“The Orthodox Union (OU) and the Rabbinical Council of America (RCA) strongly urge all parents to vaccinate their healthy children on the timetable recommended by their pediatrician.”

Statement on Vaccinations from the OU and Rabbinical Council of America

People in these communities have been misled and misinformed by anti-vaccine propaganda.

How about we make folks who push anti-vaccine misinformation wear dunce caps?
How about dunce caps on folks who push anti-vaccine misinformation?

Don’t let them make it worse.

More on the Emergency Declaration in Rockland County

More Measles Myths

It’s kind of sad that some folks still believe many of the measles myths that were being told in 1963.

Folks once accepted measles as inevitable because they had no choice, but that changed when we got a vaccine.
Measles was long known as a harmless killer

Wait, measles isn’t harmless?

But what about that Brady Bunch episode!?!

More Measles Myths

What other myths about measles have you heard?

Have you heard that folks never worried about measles before we had a vaccine? That it never even made the newspaper?

There were newspaper articles warning about measles in 1959 - a measles year.

The other myths they push are just as easily disproven

Which of these myths do you believe?

Which ones are keeping you from vaccinating and protecting your kids?

More on Measles Myths

Is a Vaccine Strain Causing The Latest Measles Outbreak?

What’s the first question anti-vaccine folks start asking whenever we see a large outbreak of measles?

No, it’s not how can I get my kids vaccinated and protected so that they don’t get measles…

It is whether or not it a vaccine strain of measles started the outbreak.

That’s not how any of this works…

Where do folks get all of this stuff about genotypes and vaccine strains? I wonder…

Dr. Bob had no facts, but still posted that a vaccine strain of measles could have killed a woman who got caught up in the last measles outbreak in Washington.

Yup.

The usual suspects.

Is a Vaccine Strain Causing The Latest Measles Outbreak?

Why do folks who intentionally don’t vaccinate their kids desperately want these measles outbreaks to be caused by a vaccine strain?

Because then it isn’t their fault that their kids are at risk of getting a life-threatening disease!

It’s never a vaccine strain though.

Remember the Disneyland measles outbreak. A lot of folks were talking about vaccine strains when it first started.

“…California patients were genotyped; all were measles genotype B3, which has caused a large outbreak recently in the Philippines…”

Measles Outbreak — California, Dec 2014–Feb 2015

It wasn’t a vaccine strain.

OutbreaksYearGenotype
Minnesota2017B3
Tennessee2016B3
California2015B3
Florida2013D8
California2014B3, D8
Brooklyn2013D8
North Carolina2013D8
Minnesota2011B3
Washington, Illinois2008D5, D4

For example, during 2011, 222 cases of measles and 17 outbreaks were reported in the United States, with most cases originating from just five countries (France, Italy, Romania, Spain, and Germany). Six different genotypes were identified, including B3, D4, G3, D8, H1, and D9. No vaccine strains…

And no, it doesn’t matter that the vaccine strain of measles, genotype A, differs from all of the wild strains of measles we see in the outbreaks.

“Vaccine induced immunity protects against all virus strains. Measles is considered a monotypic virus despite the genetic variations.”

Factsheet about measles

Unlike the flu, HPV, and pneumococcal bacteria, in which vaccines only protect against different serotypes, in the case of measles, the genotype simply helps us figure out where the measles case came from.

And no, the latest outbreak, wherever it is, wasn’t caused by shedding from a vaccine.

But if it isn’t the vaccine strain, then why do they that is it important to rapidly identify wild strains vs vaccine strains?

“During measles outbreaks, it is important to be able to rapidly distinguish between measles cases and vaccine reactions to avoid unnecessary outbreak response measures such as case isolation and contact investigations.”

Roy et al on Rapid Identification of Measles Virus Vaccine Genotype by Real-Time PCR

That’s easy to answer.

Outbreaks typically trigger a lot of folks to get vaccinated. While that’s great, one possible problem is that some of those folks might develop a fever and/or rash after their MMR vaccine. So it is important to quickly figure out whether they are part of the outbreak and have a wild strain (maybe they were exposed before their vaccine could start to work) or are having a common, mild vaccine reaction.

But couldn’t they have vaccine-associated measles if they have a rash and fever and a vaccine strain? Theoretically, but then they would likely have true measles symptoms. And even in these rare case reports, the children didn’t spread the measles to anyone else.

So why are you waiting to know the genotype of the measles strain causing the outbreak in your area? Hopefully, it isn’t to help you decide whether or not to vaccinate and protect your kids. While it is interesting to know where the outbreak originated, you can bet that it isn’t a vaccine strain.

More on Vaccine Strains Causing Measles Outbreaks

What’s the Real Risk from the Contaminated Vaccines in India?

Most people understand that polio vaccines have helped to control and get us close to eradicating polio.

Many even know that there are two types of polio vaccine – the inactivated Salk vaccine and the live Sabin vaccine.

Some might even know that there are actually three strains of polio virus that we have traditionally gotten vaccinated against, and that one of those strains, type 2, has already been eradicated.

“In April 2016 a switch was implemented from trivalent OPV to bivalent OPV in routine immunization programmes.”

OPV Cessation

That’s why we have switched to using a bivalent OPV which only contains type 1 and 3 serotypes.

Contaminated Vaccines in India

What does all of this have to do with the news of contaminated vaccines in India?

“At least three batches of polio vaccines containing 1.5 lakh vials have been found contaminated with type 2 polio virus, putting at risk India’s “polio free” status as children born after April 2016 — when the type 2 virus was withdrawn worldwide including in India — do not have immunity to this particular virus, sources said.”

Unfortunately, some contaminated vaccines were actually administered to children in the Indian states of Maharashtra, Telengana, and Uttar Pradesh before the contamination was discovered.

Will these kids get polio?

No, as the vaccines weren’t contaminated with wild polio virus.

It seems that Bio-Med Private Limited was still producing and distributing polio vaccine with the type 2 vaccine virus, even though this type of vaccine was discontinued a few years ago.

Why?

We will  hopefully find out, as the managing director of Bio-Med Pvt Ltd has been arrested, but we don’t know yet.

We do know that there is little risk from these vaccines and they won’t put India’s “polio free” status at risk.

Why would there be any risk from kids getting an extra vaccine virus strain?

It’s because the type 2 strain of polio is the most likely to cause cVDPV, or outbreaks of polio that are actually caused by the polio vaccine.

Fortunately, these outbreaks are very rare.

A dose of IPV is the backup plan to make sure a problems with the switch to bOPV doesn't end up in a tragedy.
A dose of IPV is the backup plan to make sure any problems with the switch to bOPV doesn’t end up in a tragedy.

But kids in the area are at even less at risk from these “contaminated” vaccines because as part of the plan to switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV), they likely got a dose of IPV, which includes protection against all three polio virus strains.

Not that this means that it isn’t a problem that a company was making and distributing a vaccine that kids shouldn’t have been getting.

That is terrible!

It just isn’t as big a danger as some folks are making it out to be. It is extremely unlikely that there will be any cases of polio in India, and definitely not a resurgence of polio because of these vaccines, as some have suggested.

The real risk will be that an isolated event will scare folks away from getting vaccinated and protected, even though we know that these events are rare and that vaccines are safe.

More on Contaminated Vaccines in India

How Do They Figure out Who Starts an Outbreak?

As we continue to see outbreaks of vaccine-preventable diseases in the post-vaccination era, it is important that these outbreaks be quickly contained.

But it is important to understand that these outbreaks don’t simply stop on there own. A lot of work goes into containing them.

Working to Contain an Outbreak

And that work containing outbreaks is expensive. Much more expensive than simply getting vaccinated.

For example, the total personnel time and total direct cost to the New York City Department of Health and Mental Hygiene responding to and controlling the 2013 outbreak in NYC were calculated to be at least $394,448 and 10,054 personnel hours.

Why it is so expensive is easy to see once you understand all of the work that goes into containing an outbreak. Work that is done by your local health department as soon as a case of measles, or other vaccine-preventable disease, is suspected.

Work that, for a measles outbreak for example, includes:

  • initiating a case and contact investigation
  • quickly confirming that the patient actually has measles, including testing
  • assessing the potential for further spread – identifying contacts who aren’t immune to measles and are at risk for getting measles
  • isolating people with measles and quarantining contacts who aren’t immune to measles for at least 21 days after the start of the measles rash in the last case of measles in the area, including everyone who is intentionally unvaccinated
  • offering postexposure vaccination, a dose of the MMR vaccine within 72 hours of exposure to contacts who are not fully immune so that they can get some protection maybe don’t have to be quarantined
  • having targeted immunization clinics in the affected population, such as a school or church, to get as many people vaccinated as possible, even after 72 hours, so they have can be protected in the future

That’s an awful lot of work.

Work that continues until the outbreak officially ends.

Finding the Source of an Outbreak

Another big part of the work that goes on to contain an outbreak is identifying the source of the outbreak.

Was it someone who had recently been traveling overseas, a visitor from out of the country, or someone that was already part of an another outbreak?

Why is that so important?

If you don’t find the source of the outbreak, then you can’t be sure that you have found all of the people that have been exposed, and the outbreak might go on for an extended period of time.

And no, it is never shedding, a vaccine strain, or a recently vaccinated child that causes these measles outbreaks.

Anatomy of a Measles Outbreak

A closer look at the measles outbreak in San Diego, California in 2008 can help folks understand even better what happens during one of these outbreaks.

A 7-year-old who is unvaccinated because his parents have a personal belief vaccine exemption travels to Switzerland with his family.

A week after returning home from the trip, he gets sick, but returns to school after a few days. He then develops a rash and sees his family physician, followed by his pediatrician, and then makes a trip to the emergency room because he continues to have a high fever and rash (classic measles symptoms).

He is eventually diagnosed with measles, but not before eleven other children are infected with measles. This includes two of his siblings, five children in his school, and four children who were exposed at his pediatrician’s office.

It is not as simple as that though.

During this measles outbreak:

  • Three of the children who became infected were younger than 12 months of age, and were therefore too young to have been vaccinated
  • Eight of the nine children who were at least 12 months old were intentionally unvaccinated because they also had personal belief vaccine exemptions
  • About 70 children were placed under voluntary quarantine for 21 days after their last exposure because they were exposed to one of the measles cases and either didn’t want to be vaccinated or were too young
  • One of the infants with measles traveled to Hawaii, raising fears that the measles outbreak could spread there too

All together, 839 people were exposed to the measles virus.

This family didn't have a choice about their son getting sick - he was too young to be vaccinated when he was exposed to an unvaccinated child with measles.
This family didn’t have a choice about their son getting sick – he was too young to be vaccinated when he was exposed to an unvaccinated child with measles.

At least one of them was a 10-month-old infant who got infected at his well child checkup, was too young to have gotten the MMR vaccine yet, and ended up spending three days in the hospital – time his parents spent “fearing we might lose our baby boy.”

The parents of this 10-month-old weren’t looking for a vaccine exemption and didn’t want their child to catch measles, a life-threatening, vaccine-preventable disease. Instead, they were counting on herd immunity to protect him until their child could be protected with an MMR vaccine. They were one of “those who come into contact with them” that got caught up in a decision of some other parents to not vaccinate their child.

The kids who are at risk and get a vaccine-preventable disease because they are too young to get vaccinated, have an immune system problem that prevents them from getting immunized or their vaccine from working, and the kids who simply didn’t get protected from a vaccine are the hidden costs of these measles outbreaks that we don’t hear about often enough.

What to Know About Finding the Source of an Outbreak

Without all of the hard work that goes into containing outbreaks, the outbreaks of measles, pertussis, mumps, hepatitis A, and other vaccine preventable diseases would be even bigger.

More on Finding the Source of an Outbreak

 

Is Mutating Mumps More Than the MMR Can Manage?

It is not news that we have been seeing more cases of mumps in recent years.

It is also isn’t news that many of these folks are vaccinated.

“Long Beach has been hit with a mumps outbreak that is vaccine-resistant. According to health officials in the Long Island town, almost two dozen individuals are believed to have contracted the virus, with four confirmed cases and at least 14 suspected ones.”

Natural News

That sites like Natural News is putting out misinformation about vaccine-resistant strains of mumps also shouldn’t be news to anyone.

Why Do Folks Think That Vaccine-Resistant Viruses Are Causing Mumps Outbreaks?

So are vaccine-resistant mumps viruses causing outbreaks?

There is no good evidence of that and plenty of evidence that our current vaccines, even though they aren’t perfect, do cover all wild strains of mumps.

Unfortunately, it might not be surprising that some folks are confused about vaccine-resistant mumps viruses, when we have health officials saying things like:

“Sometimes nature throws a strain at us that might have mutated a little bit, and coverage of the vaccine is not 100 percent.”

Dr. Lawrence Eisenstein, Nassau County Health Commissioner

Dr. Eisenstein’s “might have mutated a little bit” comment got twisted into “the outbreak is most likely attributable to a new strain of the virus that is resistant to vaccines” by health reporters

And out of Arkansas, where there have also been large mumps outbreaks:

“We are actually to the point that we are worried that this vaccine may indeed not be protecting against the strain of mumps that is circulating as well as it could.”

Dr. Dirk Haselow, Arkansas State Epidemiologist

Of course, to say that the vaccine may not be protecting folks “as well as it could” doesn’t mean it doesn’t work because the wild type mumps virus has evolved or mutated enough to surmount our current MMR vaccine.

Is Mutating Mumps More Than the MMR Can Manage?

Although anything is possible, we fortunately have plenty of research that says that the mumps virus hasn’t mutated and that the MMR still works.

During an outbreak, universities make sure students are up-to-date with their MMR vaccines.
During an outbreak of mumps, some kids are getting a third dose of the MMR vaccine.

In fact, although the MMR vaccine is made from the A strain or genotype of mumps, it provides good protection against all 12 known strains of wild mumps viruses, including genotype G that has been causing most of the recent outbreaks.

But how can it cover a different strain of virus that isn’t in the vaccine?

Because not all viruses and vaccines are like influenza.

“The genotyping of the mumps virus is based on the Small Hydrophobic (SH) protein, a nonstructural protein and genetically the most variable one. Based on the SH-protein 12 different mumps viruses were detected up to now. In recent epidemics in Western countries the genotype G was mainly detected, while the mumps viruses used in the live attenuated mumps vaccines belong to genotype A (Jeryl Lynn) and to a lesser extent to genotype B (Urabe). However, antibodies against the SH protein have not yet been observed in human serum. It is, therefore, unlikely that antibodies against the SH protein play an important role in antibody-mediated virus neutralization.”

Sabbe et al. on The resurgence of mumps and pertussis

It is well known that you need a very specific match of the flu vaccine to the wild flu virus that is going around to get good protection, but for many other viruses, the differences that determine the strain or genotype have nothing to do with how antibodies will recognize the virus.

“Since mumps virus is monotypic, vaccine from any strain should provide lifelong protection against subsequent infection.”

Palacios et al. on Molecular Identification of Mumps Virus Genotypes from Clinical Samples: Standardized Method of Analysis

Like measles, mumps is a monotypic virus.

“Studies have demonstrated that blood sera from vaccinated persons cross-neutralizes currently circulating mumps strains.”

CDC on Mumps for Healthcare Providers

And like measles, the mumps vaccine (MMR), protects against all strains of wild mumps viruses.

“Compared with attack rates of 31.8%–42.9% among unvaccinated individuals, attack rates among recipients of 1 dose and 2 doses of the Jeryl Lynn vaccine strain were 4%–13.6% and 2.2%–3.6%, respectively.”

Dayan et al. on Mumps Outbreaks in Vaccinated Populations: Are Available Mumps Vaccines Effective Enough to Prevent Outbreaks?

And like other vaccines, the mumps vaccine (MMR) works.

Waning immunity may be an issue, but that certainly isn’t a reason to skip or delay this vaccine and put your kids, and everyone else, at risk to get mumps.

What to Know About Mumps Strains and Outbreaks

The MMR vaccines covers all strains of mumps and getting fully vaccinated is the best way to make sure your kids don’t get mumps.

More on Mumps Strains and Outbreaks