Tag: vitamin C

The Case for Vitamin C to Treat Serious Infections

Why do some folks think that high doses of vitamin C will cure anything and everything, including life-threatening infections?

Vitamin C is a cure for scurvy...
Vitamin C is a cure for scurvy…

The usual suspects.

The Case for Vitamin C to Treat Serious Infections

Sure, most of us know that Linus Pauling started the vitamin C craze way back in the 1970s.

But even though it has been shown time and again that high doses of vitamin C have no big health benefits, alternative medicine type folks keep pushing it, even as they advocate against newborns getting much needed vitamin K shots.

IV infusions are not cheap and have no health benefits.

There has even talk that it might help patients with sepsis in the ICU, a treatment that has come up again because of a clinical trial involving COVID-19.

Is it a coincidence that the measles epidemic in Samoa was under control soon after Edwin Tamasese was put in jail?

Will it work?

Some studies are still being done on septic patients in the ICU to see if they benefit from high dose vitamin C infusions.

“VICTAS is a clinical trial to test the combination of Vitamin C, thiamine and hydrocortisone for the treatment of sepsis.. It will be conducted across 30 to 40 major academic medical centers in the United States and will enroll at least 500 patients. All patients in the clinical trial will receive the regular best intensive care available for sepsis, and half of the patients will additionally receive vitamin C, thiamine and hydrocortisone. By testing a large number of patients, the doctors can then see if the group of patients that got the combination of medications did better than the group that did not.”

About VICTAS

Other studies have been completed already.

“In patients with septic shock, treatment with intravenous vitamin C, hydrocortisone, and thiamine, compared with intravenous hydrocortisone alone, did not significantly improve the duration of time alive and free of vasopressor administration over 7 days. The finding suggests that treatment with intravenous vitamin C, hydrocortisone, and thiamine does not lead to a more rapid resolution of septic shock compared with intravenous hydrocortisone alone.”

Fujii et al on Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

And most show no benefit of high dose vitamin C therapy.

“The results of the clinical trial by Fujii et al in this issue of JAMA, added to the cumulative evidence from 13 different studies performed in 10 different countries, indicate that high-dose vitamin C with or without thiamine and steroids does not provide significant survival benefits for patients with sepsis or septic shock. Given that other studies are forthcoming, there appears to be no immediate justification for adoption of high-dose vitamin C, alone or in combination, as a component of treatment for sepsis. Moreover, use of high-dose vitamin C in combination or alone “just in case” or as a “measure of last resort,” aside from providing no survival benefits, could have several other potential consequences, including diverting funding from needed research to examine sepsis mechanisms and diagnostics; stifling the development of other sepsis therapies; perpetuating false hopes for patients, families, and clinicians; and delaying proven lifesaving therapies such as prompt initiation of antibiotic therapy.”

Andre Kalil on Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis

Which is too bad, as it would be great if sepsis could be cured or easily treated with vitamin C.

Sepsis is a terrible disease!

But why do folks who are against vaccines get so excited about vitamin C treatments?

That’s simple.

If you can easily treat such serious and life-threatening diseases with a little, or even a lot of vitamin C, then you can feel better about skipping or delaying your vaccines. After all, if you are unvaccinated and get sick, you have vitamin C to fall back on, right?

Unfortunately, that’s not how it works.

“Prevent infections by following infection control practices (e.g. hand hygiene, catheter removal) and ensuring patients receive recommended vaccines.”

CDC on Sepsis Healthcare Professional Information

The best way to protect yourself from sepsis is to avoid the infections that can lead to sepsis. And getting vaccinated and protected is certainly a good way to avoid infections, even though not all of the germs that cause sepsis are vaccine preventable.

More on Vitamin C

The Timeline of the Measles Epidemic in Samoa

The timeline of the measles epidemic in Samoa seems fairly easy to understand.

Vaccination rates went down, the people in Samoa got caught up in the rise in measles cases and outbreaks happening all over the world, and they soon had a measles epidemic on their hands, with lots of kids dying.

In an outbreak situation, everyone who is not immune would need to get two doses of a measles containing vaccine and that's why you need 215,000 doses of measles vaccine... And despite what Sherri Tenpenny might think, everyone on Samoa is still not vaccinated yet.
In an outbreak situation, everyone who is not immune would need to get two doses of a measles containing vaccine and that’s why you need 215,000 doses of measles vaccine… And despite what Sherri Tenpenny might think, everyone on Samoa is still not vaccinated yet.

Unfortunately, anti-vaccine folks continue to exploit the tragedy, trying to make it sound like vaccines actually caused the epidemic.

“The Samoa Measles Appeal is being launched by the Government of Samoa to receive financial assistance from partners to support national efforts to contain the outbreak, to effectively treat people who contracted measles, and to achieve herd immunity for long term protection of the population.”

National Measles Response and Recovery Appeal

They are even making up conspiracy theories about the money the Government of Samoa is requesting to help control the epidemic and prevent future outbreaks.

The Timeline of the Measles Epidemic in Samoa

Maybe what is happening in Samoa isn’t so easy to understand…

Let’s give it a try!

To truly understand what is happening in Samoa, you have to go back a little further than when the epidemic started.

In fact, we have to go all of the way back to July 2018, when two young children died very shortly after getting their routine MMR vaccines. Although they died because of a mixup between the vaccine diluent and a powerful anesthetic, the tragic deaths led to the suspension of all vaccinations in the country.

Taylor Winterstein was planning an anti-vax workshop in Samoa in June.
Taylor Winterstein was planning an anti-vax workshop in Samoa in June.

And while the suspension was eventually reversed, they continued to hold MMR vaccinations for another nine months, until April 15, 2019.

Bobby Kennedy actually wrote a letter to the Prime Minister of Samoa on November 19th making every effort to blame the epidemic on a defective MMR vaccine, mutant measles strains, or vaccine strain measles.
Bobby Kennedy actually wrote a letter to the Prime Minister of Samoa on November 19th making every effort to blame the epidemic on a defective MMR vaccine, mutant measles strains, or vaccine strain measles.

Combine that with the efforts of anti-vax folks and it is easy to see how immunization rates in Samoa eventually tumbled to a low of just 30%!

What happened next?

On October 9, we got the first report of a measles case in Samoa and that it was related to a someone who visited from New Zealand for a conference at the end of August.

But by the time of that first report, at least 86 people had already been tested for suspected measles!

“Of the 28 specimens of suspected measles cases sent to Victorian Infectious Disease Reference Laboratory Melbourne, Australia on the 30th Sept 2019, twelve (12) results have been received over the week end. Of these twelve there were four confirmed cases; one adult and three children. All have been treated and discharged with no complications.

On the 2nd of October 2019, we sent another 8 specimens of suspected measles cases. Current results received this afternoon of these eight specimens sent revealed three new confirmed cases. Of these three positive cases, two were children under five years and 1 was an adult of 22 years old. All have been treated and discharged.

A total of seven confirmed cases have been reported to date. In anticipation, we now confirm a Measles Epidemic.”

Ministry of Health Press Release 1 – Measles Epidemic (October 16)

With that many cases already, it should be obvious that the measles outbreak in Samoa started in late September. That explains why UNICEF had begun to send measles vaccines and vitamin A to Samoa in early October.

Measles cases in Samoa began in September, which is why UNICEF began sending vaccines in October.
Wait. If the outbreak is caused by the vaccine strain (A genotype), why are folks testing positive for the D8 strain?

And that should put to rest the myth that this is some kind of unnatural, vaccine induced outbreak that got started because of the UNICEF vaccines.

“The deceased child of one year two months was admitted on the 8th October 2019 with a history of febrile convulsions, cough and skin rash typical of measles associated with severe dehydration. Verification of immunization status for this child revealed that he has not been vaccinated against measles.”

Ministry of Health Press Release 1 – Measles Epidemic

Tragically, we very soon saw the first measles death (October 15) in Samoa, an unvaccinated toddler. With continued cases, they soon declared a measles epidemic on October 16.

With continued cases and deaths, the Government of Samoa closed all preschools and daycare centers on October 31.

On November 8, they lowered the age to get the first dose MMR in Samoa to 6 months.

It wasn’t long before the Government of Samoa declared a full fledged state of emergency (November 15), closing schools, restricting children from gathering in public, and making vaccination mandatory.

“The outbreaks in Samoa and Tonga are caused by the D8 strain (genotype) of measles virus. Measles vaccine coverage varies in Pacific island countries and areas, ranging from 31% in Samoa to 99% in the Cook Islands, Nauru and Niue.”

Measles Outbreak in the Pacific – Situation Report No 1, 22 November, 2019

It was at this time that more help came from New Zealand, 12 nurses to help administer vaccines. Australia also soon sent a team of 34 doctors and nurses to help at Samoa’s main hospital in the capital Apia.

“Samoa’s government is warning anyone trying to discourage people from getting measles vaccinations to stop it.”

Measles Update: Samoa warns against anti-vaxxers; issues new emergency orders

And now, although there have been some roadblocks put up by anti-vaxxers both in and out of Samoa, with lots of help, they are hopefully getting their epidemic under control.

“As of December 6th, 2019, approximately 89% of all eligible people in Samoa have been vaccinated against measles.”

National Emergency Operation Centre: Update on the measles outbreak (Press Release 21) December 7, 2019

In fact, many people were vaccinated when the Government of Samoa shut down on December 5th and 6th.

“On 03/12, the Government announced that a nationwide mass vaccination will take place on Thursday and Friday (05 + 06/12) and all public services (excluding power and water, police, and health services) as well as the private sector (with few exceptions) will be shut down from 7 am – 5 pm to enforce the mass vaccination programme. Citizens were asked to stay at their residences and await the visit of mobile vaccination teams. There are 128 teams carrying out the mass vaccination campaign during this period.”

National Measles Response and Recovery Appeal, 6 December 2019

During the door to door mass vaccination campaign, families were told to stay home and hang red flags outside their homes if they needed to be vaccinated.

Photo courtesy of the Government of Samoa.
Photo courtesy of the Government of Samoa.

Amazingly, with all of the cases and deaths, some folks resisted and didn’t want to be vaccinated and protected.

Still wondering why some parents are scared and don't want their kids vaccinated?
Still wondering why some parents are scared and don’t want their kids vaccinated?

They turned the vaccination teams away!

So much for the idea of forced vaccination, right?

There have been 70 deaths in the measles epidemic in Samoa.
An update from Samoa on December 9th.

Most have gotten vaccinated and protected though.

They understand that while traditional healers might still be popular in Samoa, they can not be used for life-threatening diseases such as measles.

In addition to overloading kids with vitamin C, a traditional healer working with Jim Meehan was arrested for making many claims that scared people away from getting vaccinated and protected.
In addition to overloading kids with vitamin C, a traditional healer working with Jim Meehan was arrested on December 6 for making many claims that scared people away from getting vaccinated and protected.

So what’s next?

The measles epidemic in Samoa has greatly slowed down as most folks are now vaccinated and protected.
The measles epidemic in Samoa has greatly slowed down as most folks are now vaccinated and protected.

While it isn’t over yet, hopefully we are in the ending stages of their epidemic, as many people have now been vaccinated and protected with at least one dose of a measles containing vaccine.

And hopefully everyone has learned a big lesson and this epidemic will serve as a warning to everyone to vaccinate and protect their kids.

Samoan children should have been vaccinated and protected.
Samoan children should have been vaccinated and protected.

They have hopefully also learned to not listen to anti-vax folks, especially those who would try and exploit this kind of epidemic to push their propaganda.

More on the Measles Epidemic in Samoa

Jim Meehan Supporting a Farmer Helps Explain the Deaths in Samoa

In case you need to be caught up, there is a measles epidemic in Samoa and over 50 kids have already died.

While that easily dwarfs the number of deaths in many other countries, where there have been thousands of deaths, Samoa has been getting some extra attention because some of the blame rests with anti-vax influence on the island nation.

Taylor Winterstein compared the plan to vaccinate everyone against measles to stop the outbreak to Nazi Germany!

Samoa even got a visit from Bobby Kennedy last June!

Jim Meehan Supporting a Farmer Helps Explain the Deaths in Samoa

It is even more amazing that many of these folks have been doubling down on their anti-vax activism even as measles deaths have continued to climb.

Edwin Tamasese is an holistic healer in Samoa.
I wonder what Jim Meehan thinks caused those birth defects in Brazil…

It seems that Edwin Tamasese, a farmer in Samoa who is also described as a holistic healer, is being advised on how to treat kids with measles by James Meehan, an ophthalmologist in Oklahoma who now practices integrative and functional medicine.

How do either have the training or background to help sick kids in a measles epidemic?

That they don’t is easy to see from Meehan’s letter of support…

The last thing folks in Samoa need is advice from Jim Meehan!
The last thing folks in Samoa need is advice from Jim Meehan!

Wait, why would anyone vaccinate a child who was already infected with measles?

Probably because it is a part of routine measles postexposure prophylaxis guidelines. In fact, giving a dose of MMR within a few days of exposure to someone with measles can reduce their risk of getting sick with measles or of developing complications of measles.

Of course, you wouldn’t actually give the MMR vaccine to someone who was already sick with measles though. Instead of simply being infected with measles, that would be someone with measles disease.

Big difference!

Antibiotics don't treat viral infections, but they do treat secondary bacterial diseases and superinfections that often complicate measles infections.

There are no indications for antibiotics to treat uncomplicated viral diseases, unfortunately, secondary bacterial diseases can occur and do need to be treated.

“These results document that MV infection can suppress both innate and adaptive immune responses and lead to increased susceptibility to bacterial infection.”

Slifka et al on Measles virus infection results in suppression of both innate and adaptive immune responses to secondary bacterial infection

In fact, it is these secondary bacterial super-infections, including pneumonia and mastoiditis, that can make measles so deadly.

“Mortality from measles is predominantly caused by complicating bacterial infections.”

Factsheet about measles

It is a big reason that kids with measles, a viral infection, likely need to be treated with antibiotics.

It is typically only recommended that parents treat fever if their child is very uncomfortable.
It is typically only recommended that parents treat fever if their child is very uncomfortable.

Kids with measles typically have a high fever and are very irritable.

While we have been moving towards an approach of letting fevers run their course these days, in case fever does have some beneficial effects, there are also studies that have shown that in critically ill patients, fever is associated with increased mortality.

Measles is not mutating.
Mutating measles? Where have we heard that before?

Why do we genotype measles strains?

So that we know where outbreaks originated from.

Unlike some other infections, the genotype doesn’t help you figure out whether or not the vaccine will work against it. Measles is a monotypic virus. The MMR vaccine protects against all measles strains.

“The outbreaks in Samoa and Tonga are caused by the D8 strain (genotype) of measles virus.”

Measles Outbreak in the Pacific – Situation Report No 2, 26 November 2019

An no, for the millionth time, 38% of the measles cases in the Disneyland outbreak were not caused by the vaccine strain!

Those folks with the vaccine strain were the ones who were recently vaccinated and had a “febrile rash illness,” a common side effect of the vaccine.

They did not have measles!

While vaccinating someone who is truly immunosuppressed with a live vaccine is contraindicated, it seems like Meehan thinks that most of the folks on Samoa are immunosuppressed and shouldn’t be vaccinated!

The kids are dying because they aren't vaccinated and protected!
Not the measles virus??? The kids are dying because they aren’t vaccinated and protected!

There is a state of emergency in Samoa that has closed schools, banned public gatherings, and mandated vaccines, as they attempt to get their measles epidemic under control. They are also getting help from UNICEF, the New Zealand Red Cross, UK’s Emergency Medical Team (UK EMT), the Australian Medical Assistance Team (AUSMAT), and the New Zealand Medical Assistance Team (NZMAT).

More help is coming from the CDC and the EUCPM.

How much vitamin C are the kids on Tamasese's protocol getting?
How much vitamin C are these kids getting? 3000mg? 5000mg? Since too much vitamin C causes diarrhea and nausea, how much will they take “until stomach runs?” Diarrhea and dehydration are already complications of measles…

They do not need folks like Tamasese and Meehan interfering with these efforts because they think they can do it better, even as they scare parents away from vaccinating and protecting their kids – the one thing that will end the epidemic.

It should be noted that as much as anti-vax folks are crowing about Tamasese and Meehan’s efforts to get kids vitamin A, their protocol severely under doses kids!

The WHO has a protocol for giving kids high doses of vitamin A when they have measles.
The WHO has a protocol for giving kids high doses of vitamin A when they have measles.

Anyway, mega doses of vitamin A are most helpful in reducing mortality in hospitalized kids with measles. It is also important to keep in mind that vitamin A only reduces mortality – it doesn’t eliminate it. Vitamin A is not a cure for measles.

And the mega doses of vitamin C they are giving aren’t going to help prevent complications. They are just giving the kids diarrhea, which is not a good thing if they might already be malnourished!

What’s the biggest takeaway from the Samoa epidemic?

As we see more measles, we will see more people die with measles.

Measles is deadly.

This type of anti-vax propaganda is the reason that parents might think that vaccines are toxic...
This type of anti-vax propaganda is the reason that parents might think that vaccines are toxic…

Get vaccinated and protected with two doses of MMR and prevent these outbreaks.

More on Jim Meehan and Samoa