Tag: risks

About those Stanley Plotkin Videos…

Stanley Plotkin is typically described as “a prominent figure in the history of vaccinology, whose work on vaccine development has led to a significant reduction in morbidity and mortality from infectious diseases in the second part of 20th century. “

Why?

For one thing, he developed the rubella vaccine that we still use today.

He also worked on vaccines against CMV, polio, chicken pox, rabies, and rotavirus.

What Did Stanley Plotkin Say While He Was Under Oath?

That’s not why anti-vaccine folks are talking about him these days, or maybe it is…

Mostly, they are misinterpreting comments he made during a videotaped deposition.

“Lori Matheson is fighting her ex-husband, Michael Schmitt, for the right to decide if their two-year-old daughter should be vaccinated.”

Michigan anti-vaccination case to goes to court

A videotaped deposition in a case involving parents who disagreed about vaccinating their daughter…

Even though it isn't his exact quote and anti-vaccine folks don't give you the full context of what he was talking about, it is clear that Dr. Plotkin simply meant that you can't prove a negative.
Even though it isn’t his exact quote and anti-vaccine folks don’t give you the full context of what he was talking about, it is clear that Dr. Plotkin simply meant that you can’t prove a negative.

What do anti-vaccine folks think he said?

“I would say it is logically true that you cannot say, you cannot point to proof that it doesn’t cause autism. ”

Stanley Plotkin, M.D.

No, he isn’t saying that vaccines are associated with autism.

“I could not say that as a, as a scientist or a logician. But I can say as a physician that, no, they do not cause autism, because as a physician, I have to take the whole body of scientific information into consideration when I make a recommendation for a child.”

Stanley Plotkin, M.D.

All he is saying is that you can’t definitively prove a negative.

One of the different things in communicating the fact that there is no link is that science and English are not really the same language. So when a scientist says, “We have no evidence that there’s a link between vaccines and autism,” what they’re really saying is, “We are as positive as someone can humanly be that there’s no link.”
Seth Mnookin explain it well – One of the different things in communicating the fact that there is no link is that science and English are not really the same language. So when a scientist says, “We have no evidence that there’s a link between vaccines and autism,” what they’re really saying is, “We are as positive as someone can humanly be that there’s no link.”

For example, just because I have never seen a black swan, I can’t use that as proof that black swans don’t exist somewhere. After all, I haven’t been everywhere.

“…scientists can be at a real disadvantage in this debate because they, by their nature, are careful in how they present their conclusions.”

Vaccines: Last Week Tonight with John Oliver (HBO)

What else do anti-vaccine folks have a problem with?

Remember the rubella vaccine he developed?

“After a detour to obtain credentials as a pediatrician, I returned to Wistarto work on rubella. Those years were fraught with advances and reverses, controversy and eventually vindication. The pandemic of CRS babies in 1964-65 was an important stimulus to research on the vaccine. “

Stanley Plotkin’s On the Occasion of the Presentation Of The 2002 Albert B. Sabin Gold Medal

During the rubella epidemic of 1964-65, there were 12.5 million rubella virus infections, which “resulted in 11,250 therapeutic or spontaneous abortions, 2,100 neonatal deaths, and 20,000 infants born with congenital rubella syndrome.”

And that’s just in the United States.

The controversy?

“There were only two fetuses involved in making vaccines. When fetal strains of, fibroblast strains were first developed, I was involved in that work trying to characterize those cells; but they were not used to make vaccines.”

Stanley Plotkin, M.D.

It is well known (this isn’t some shocking truth as some are trying to push) that some vaccines are made with fetal embryo fibroblast cells (the WI-38 and MRC-5 cells) from cell lines that are derived (they can replicate infinitely) from two electively terminated pregnancies (abortions) in the 1960s.

Those two fetuses weren’t the only two fetuses ever used in research though, they were just the only ones used to actually make vaccines.

“Human diploid cell strains (HDCSs) are batches of cells that are currently used for different purposes, including culturing viruses for the manufacturing of vaccines”

A brief history of human diploid cell strains.

They had to get to the point where they knew how to make vaccines in human cell lines though and that’s what he is talking about in the deposition.

“Q. In any event, so we have 76 in this study. Would you approximate it’s been a few hundred fetuses?


A. Oh, no, I don’t think it was that many. Probably not many more than in this paper. And I should stipulate that we had nothing to do with the cause of the abortion.”

It took some experimentation to find the right kind of cells and the right methods, but ultimately, they found that fetal embryo fibroblast cells were the best to use to grow many viruses.

Copies of those same cells are still used today.

What about the other “issues” brought up in the deposition?

Did he experiment on orphans, people who were mentally handicapped, or those who lived in third world countries?

“I don’t remember specifically, but it’s possible. And, again, I repeat that in the 1960s, that was more or less common practice. I’ve since changed my mind. But those were, that was a long time ago.”

Stanley Plotkin, M.D.

Those were different times, but Dr. Plotkin’s vaccine studies weren’t unethical and weren’t like what was done at Willowbrook, in which children were purposely exposed to hepatitis, with the justification that most of them ended up getting it anyway.

Surprisingly, in the early 1970s, there was still some debate about the ethics of doing experiments on children, and as you can see, using ableist language to describe children with a disability.
Surprisingly, in the early 1970s, there was still some debate about the ethics of doing experiments on children, and as you can see, using ableist language to describe children with a disability.

And from those times, experts developed the rules for how things are now done.

Ironically, anti-vaccine folks are pushing this stuff about Plotkin, but don’t understand why leaving kids completely unvaccinated and unprotected in a study is unethical.

“One is morally free to use the vaccine regardless of its historical association with abortion. The reason is that the risk to public health, if one chooses not to vaccinate, outweighs the legitimate concern about the origins of the vaccine. This is especially important for parents, who have a moral obligation to protect the life and health of their children and those around them.”

National Catholic Bioethics Center FAQ on the Use of Vaccines

Or why it’s immoral to push anti-vaccine propaganda or put others at risk to get a vaccine-preventable disease.

“Results indicate that the total number of cases of poliomyelitis, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A averted or treated with WI-38 related vaccines was 198 million in the U.S. and 4.5 billion globally (720 million in Africa; 387 million in Latin America and the Caribbean; 2.7 billion in Asia; and 455 million in Europe). The total number of deaths averted from these same diseases was approximately 450,000 in the U.S., and 10.3 million globally (1.6 million in Africa; 886 thousand in Latin America and the Caribbean; 6.2 million in Asia; and 1.0 million in Europe).”

Olshansky et al on The Role of the WI-38 Cell Strain in Saving Lives and Reducing Morbidity

Dr. Plotkin’s work has helped save millions of lives.

“His achievements in vaccinology are on a scale that truly can be measured in lives saved and lives restored.”

On the Occasion of the Presentation Of The 2002 Albert B. Sabin Gold Medal

And that’s why anti-vaccine folks are attacking him.

More on Stanley Plotkin

When You Ask for Vaccine Advice in an Anti-Vaccine Facebook Group…

Can you guess what happens when you ask for advice about vaccines in an anti-vaccine Facebook Group?

Meningitis is not a side effect of vaccines.

What could go wrong?

When You Ask for Vaccine Advice in an Anti-Vaccine Facebook Group…

While most of us are used to hearing about meningococcal meningitis being a big risk for teens and young adults, it is important to realize that rates of disease are also high for infants, with a second peak during adolescence.

The highest rates of meningococcal disease occurs during infancy and adolescence.

So why don’t we routinely vaccinate infants against meningococcal disease?

Many countries do, including Australia and the UK, and in the United States, high risk infants are vaccinated against meningococcal disease.

If you were on the fence but were advised by your paediatrician (Australian spelling) to get vaccinated and protected because a child in your town had just died, would you get vaccinated?

Or would you listen to folks in an anti-vaccine Facebook group who tried to convince you that meningitis was actually a side effect of getting vaccinated?

Folks who insist that deaths from vaccine-preventable disease aren’t real and that instead, they are actually vaccine-injuries?

This is the modern anti-vaccine movement.
This is the modern anti-vaccine movement.

We know what happens when you ask for vaccine advice in an anti-vaccine Facebook group. The members push their propaganda to scare you away from vaccinating and protecting your kids.

Don’t listen to them. Vaccines are safe and necessary.

More on When You Ask for Vaccine Advice in an Anti-Vaccine Facebook Group…

More Measles Hysteria From Bob Sears

Most folks remember Dr. Bob’s response to the measles outbreak in his home town.

He told folks DON’T PANIC!!!!

More Measles Hysteria From Bob Sears

That was nearly four years ago, during the Disneyland measles outbreak.

So what’s he saying now?

From panic to hysteria - Dr. Bob on the measles outbreaks.

He’s moved from panic (a sudden overpowering fright) to hysteria (behavior exhibiting overwhelming or unmanageable fear or emotional excess), but is still pushing his usual talking points.

He has changed the way he is talking about measles deaths though.

Dr. Bob Sears actually reassured parents that measles wasn't deadly in developed countries, neglecting to mention the dozens of people who have died in outbreaks in Europe - another well-nourished population with lower vaccination rates than the U.S.
Dr. Bob Sears actually reassured parents that measles wasn’t deadly in developed countries, neglecting to mention the dozens of people who have died in outbreaks in Europe – another well-nourished population with lower vaccination rates than the U.S.

Remember how he used to say that measles wasn’t deadly and that no one had died of measles in a long time? Now, instead of acknowledging that a woman got caught up in the 2015 outbreaks in Washington and died, he has shifted to saying that there hasn’t been a pediatric death in a long time.

Either way, it is important to understand something he leaves out. There are few deaths from measles these days because most folks are vaccinated!

When did Dr. Bob’s book about vaccines come out? The one with the alternative vaccine schedule?

Whatever his motivation, let’s take a look at what Dr. Bob is saying about measles…

“Measles hysteria is everywhere. And it’s clear the hysteria is a result of media fear around this disease, a disease every child used to get (and handle virtually without complication) not that long ago.”

Dr. Bob Sears

Not that long ago?

I’ve been a pediatrician for 22 years and I have never seen a child with measles. Neither did I have measles, as I was fortunate enough to grow up in the post-vaccine era for measles – a vaccine that has been available for since the 1960s.

And while every child did indeed once get measles, in the pre-vaccine era, not all handled it without complications, which is why measles was called the harmless killer.

Anti-vaccine folks try to hide the risks of measles in mortality rates, but the reality of it is that about 500 people died each year up until the early 1960s when the first measles vaccine was developed.

And I guess that wasn’t that long ago, after all, we had good hygiene and sanitation and healthcare at the time, and yet, a lot of people still died.

“There is another side to this measles conversation: how we’ve unintentionally shifted the burden of disease to babies and adults, both groups who are more likely to experience complications, by vaccinating all schoolchildren and losing natural immunity.”

Dr. Bob Sears

There is really only one side to this.

Folks who are intentionally not vaccinating their kids are getting measles and other vaccine-preventable diseases and are putting us all at risk to get sick.

After all, the MMR vaccine provides life-long immunity to most people. That’s not the problem.

If we went back to the pre-vaccine era, when everyone got measles naturally, as Dr. Bob seems to be advocating for, not only would those kids have to earn their immunity, but many babies (those who hadn’t had measles yet) and adults (those with immune system problems) would still be at great risk.

Are you starting to see how silly his arguments are?

We almost had measles beat!

Consider that there were just 37 measles cases in the United States in 2004. And that we have already had more than twice that amount this month alone!

And while measles was cyclical in the pre-vaccine era, it shouldn’t be when folks are vaccinated and protected. What happened to the cycles between 1997 and 2007?

“Unlike natural immunity, the measles vaccine does NOT offer lifelong protection. Estimates of its protection average around 15 years, and describe a phenomenon in the vaccine world known as “waning immunity.”

Melissa Floyd

The measles vaccine provides lifelong protection. Waning immunity only refers to protection against mumps. And no, there is no call for a third MMR dose for extra protection against measles.

“The other trend we’ve seen over the past 10 years is an increase in adult measles cases. “

Melissa Floyd

Dr. Bob’s sidekick neglects to mention that in addition to unvaccinated kis with measles, the trend is an increase in measles cases in unvaccinated adults! After all, most folks who get measles in these outbreaks are unvaccinated.

“To recap: by losing natural immunity for measles for children 5-19 years old, we’ve exposed babies, pregnant women, and adults to measles—all vulnerable groups who are more likely to experience serious complications from the disease.”

Melissa Floyd

Perhaps the only true statement that they make – “we’ve exposed babies, pregnant women, and adults to measles—all vulnerable groups who are more likely to experience serious complications from the disease.”

And no, vitamin A is not a proven therapy or measles in developed countries. It mainly helps prevent complications in kids who have a vitamin A deficiency.

Hopefully, it is becoming evident that what we need to stop is the anti-vaccine propaganda that keeps folks from vaccinating and protecting their kids. We need to stop the outbreaks.

More on More Measles Hysteria From Bob Sears

Why Are Anti-Vaccine Folks Panicking over the Measles Outbreaks?

Do you sense something in the air?

No, it’s not measles.

Ever notice that it is folks who don't vaccinate who use words like epidemic and panic whenever we have large measles outbreaks?
Ever notice that it is folks who don’t vaccinate who use words like epidemic and panic whenever we have large measles outbreaks?

It is talk of panic about measles.

Why Are Anti-Vaccine Folks Panicking over the Measles Outbreaks?

I’m not panicking.

I am definitively concerned about these outbreaks, because I understand that they put a lot of folks at unnecessary risk for getting a life-threatening disease. And I understand that these outbreaks are getting harder and harder to control, but ultimately, since more and more people get vaccinated during an outbreak, they will eventually end.

So why are anti-vaccine folks panicking?

Yes, your immune system gets to a whole new level after a natural measles infection - it resets.
Yes, your immune system gets to a whole new level after a natural measles infection – it resets.

It’s easier to be anti-vaccine and leave your kids unvaccinated and unprotected when you don’t think that you are taking much of a risk.

You likely still know it’s wrong, so cognitive dissonance pushes you to believe that vaccines don’t work, vaccine-preventable diseases aren’t that bad, vaccines are full of poison, or that you can just hide in the herd.

It gets much harder during an outbreak, when you realize that it is almost all intentionally unvaccinated kids getting sick. And typically an intentionally unvaccinated child or adult who starts the outbreak.

Why wait until an outbreak starts to get your kids vaccinated and protected or to start recommending that your patients be vaccinated and protected?
Why wait until an outbreak starts to get your kids vaccinated and protected or to start recommending that your patients be vaccinated and protected?

Is my child going to start an outbreak?

If measles is so mild, why do so many of these folks go to the ER multiple times and why do some of them get hospitalized. Why do people still die with measles?

Full Stop! Someone did die during the 2015 measles outbreaks in Washington.
Full Stop! Someone did die during the 2015 measles outbreaks in Washington.

That’s when the panic starts to set in.

Are you really doing what’s right for your child?

Who are these people I’m getting advice from and what’s their motivation?

The only "mass hysteria" is in anti-vaccine Facebook groups. Is Larry Cook using it to raise money for himself?
The only “mass hysteria” is in anti-vaccine Facebook groups. Is Larry Cook using it to raise money for himself?

Am I really supposed to skip my kid’s MMR because they did a Brady Bunch episode about all of the Brady kids getting measles?

Will I regret not vaccinating my child?

Why don’t any of the people in my Facebook groups who talk about how marvelous measles used to be in the old days talk about how they called it a “harmless killer?”

Of course, there is an easy way to stop worrying and panicking about measles and other vaccine-preventable diseases – get your kids vaccinated and protected. Vaccines are safe and necessary.

More on Measles Panic

Are Parents Faking Their Child’s Vaccine Records?

In 2015, California passed a vaccine law that removed all non-medical exemptions to getting vaccinated.

What was the response?

More kids got vaccinated.

Are Parents Faking Their Child’s Vaccine Records?

Not all of them though.

Shortly after the passage of SB277 we quickly learned of one way that parents were trying to get around the law – fake vaccine exemptions.

That’s right. Some doctors were selling fake vaccine exemptions using bogus medical symptoms, histories, and conditions.

And apparently, now that fake vaccine exemptions are getting harder to come by, some parents are simply trying to fake their child’s immunization records.

While I doubt a lot of people are faking their records, some probably are.

Some have already been caught forging their child’s vaccine records because their intentionally unvaccinated kids (who were supposed to be vaccinated) were involved in outbreaks!

Are those really your only vaccine choices? What about opting to vaccinate and protect your child?

Some others were caught writing fake vaccine exemptions, using forms from one of the doctor’s who notoriously sells fake medical vaccine exemptions!

Surprised?

You shouldn’t be.

This is the modern anti-vaccine movement.

More on Fake Vaccine Records

Are Infants More Likely to Die from Vaccines Than the Natural Diseases They Prevent?

Someone made a chart about vaccine deaths, saying it came from the CDC, and is using it to compare to an infant’s risk of natural death from vaccine-preventable disease.

Need help fact checking this image about vaccine deaths that anti-vaccine folks like to post?
Need help fact checking this image that anti-vaccine folks like to post?

Do you see any problems?

Are Infants More Likely to Die from Vaccines Than the Natural Diseases They Prevent?

Yes, that’s right.

They are misusing VAERS reports and claiming that they are vaccine deaths.

“When evaluating data from VAERS, it is important to note that for any reported event, no cause-and-effect relationship has been established. Reports of all possible associations between vaccines and adverse events (possible side effects) are filed in VAERS. Therefore, VAERS collects data on any adverse event following vaccination, be it coincidental or truly caused by a vaccine. The report of an adverse event to VAERS is not documentation that a vaccine caused the event.”

Guide to Interpreting VAERS Data

They are also leaving out the fact that deaths from vaccine-preventable diseases are low because most people are vaccinated and protected. Remember, one of the benefits of vaccines is that they got us out of the pre-vaccine era, when a lot of people died of these diseases. And most of us don’t want to go back!

As more people are vaccinated and diseases disappear, they forget how bad those diseases are, skip or delay getting their vaccines, and trigger outbreaks.
As more people are vaccinated and diseases disappear, they forget how bad those diseases are, skip or delay getting their vaccines, and trigger outbreaks. Photo by WHO

If they scare enough people with this type of propaganda though and more people skip or delay their vaccines, then the diseases will come back and the risk of death increases.

“In a review of reports of death following vaccination submitted to the Vaccine Adverse Event Reporting System (VAERS) from the early 1990s, the Institute of Medicine concluded that most were coincidental, not causally associated.”

Moro et al on Deaths Reported to the Vaccine Adverse Event Reporting System, United States, 1997–2013

That’s not even all that’s wrong with their little chart though.

They clearly say that they are talking about infants, but their chart says that it includes data for vaccines from birth to 18 years.

That should be evident when you realize that infants get neither hepatitis A nor MenB vaccines and there weren’t even any VAERS reports of deaths for infants for the hepatitis A vaccine in 2014. In fact, there has never been a report of a MenB vaccine death in VAERS for an infant.

So basically, these folks used inflated reports of deaths from VAERS that are likely coincidental and not associated with getting a vaccine and compared them to deaths that were reduced by the fact most folks are vaccinated and protected.

Don’t believe them. Vaccines are safe and necessary, with few serious side effects.

More on Misusing VAERS Reports

Why Are We Worried About 60,000 Unvaccinated Kids?

In the recent New York Times OpEd, How to Inoculate Against Anti-Vaxxers, the editorial board mentioned the 60,000 children in Texas who “remain wholly unvaccinated thanks in part to an aggressive anti-vaccine lobby.”

“But there’s like 74 million children, so I think that’s a pretty small number. I don’t know why you guys are freaking out about 60,000 really healthy babies running around. Do you know?

Hillary Simpson

Hillary Simpson obviously doesn’t understand how herd immunity works.

Do you?

Why Are We Worried About 60,000 Unvaccinated Kids?

First things first, though.

Just how many unvaccinated kids are there in Texas? How about the United States?

It is actually hard to know exactly.

It's easy to forget, with so much talk about anti-vaxxers these days, but the great majority of parents vaccinate and protect their kids!
It’s easy to forget, with so much talk about anti-vaxxers these days, but the great majority of parents vaccinate and protect their kids!

In Texas, for instance, while only a small percentage of kids get non-medical vaccine exemptions, with about 7 million children in the state (yes, there are 74 million children in the United States, but that’s not how you measure herd immunity), that adds up to a lot of unvaccinated kids.

In addition to about 60,000 unvaccinated kids in school, there are homeschooled children who aren’t vaccinated.

“We’re probably looking at more than 100,000 kids in the state of Texas who are not getting their vaccines.”

Dr. Peter J. Hotez: “A Scary Anti-Science Movement Has Become Very Strong in Texas”

But still, should we be worried about 100,000 unvaccinated kids, when there are 7 million kids in Texas?

Don’t those immunization levels still keep us above herd immunity levels of protection?

Well, they likely would, and this would indeed be less concerning if the unvaccinated children were spread out randomly throughout the entire state. Of course, that’s not what happens and we instead get clusters of unvaccinated children (and adults) in very specific schools, neighborhoods, and even churches.

There are higher numbers of unvaccinated kids in very specific parts of the states, leading to pockets where it is more likely that an outbreak could happen.
There are higher numbers of unvaccinated kids in very specific parts of the states, leading to pockets where it is more likely that an outbreak could happen.

So while it can seem like we have herd immunity levels of protection at the state or city level because of high average vaccination levels, these pockets of susceptibles who are unvaccinated and live in the same neighborhood or go to the same school (where is the Waldorf school in Texas?) can mean that we don’t have herd immunity in those places, leading to outbreaks.

And that’s why we get concerned about 60 to 100,000 unvaccinated children who:

Still, remember that the great majority of parents understand the benefits of vaccines, are not scared by anti-vaccine propaganda, and vaccinate their kids.

In 2015, for example, only 1.3% of children in the United States had received no vaccines by age 24 months. And more than 90% of children completed their primary series of vaccines.

That doesn’t mean that we shouldn’t be concerned about those who don’t, but maybe you should be a little bit more concerned about your decision to not vaccinate your kids.

More on Clusters of Unvaccinated Kids