Tag: gelatin

Anaphylaxis After Vaccines

Anaphylaxis after vaccines is a well known side effect, but just how common is it?

Anaphylaxis After Vaccines

Since it is listed as a possible reaction to nearly all vaccines and it can be life-threatening, anaphylaxis must be fairly common, right?

“Vaccine providers should be familiar with identifying immediate-type allergic reactions, including anaphylaxis, and be competent in treating these events at the time of vaccine administration. Providers should also have a plan in place to contact emergency medical services immediately in the event of a severe acute vaccine reaction.”

Preventing and Managing Adverse Reactions

After all, pediatricians even get warned to have a plan in place and to be prepared to treat children just in case they develop anaphylaxis after getting their vaccines.

Your pediatrician will likely have an EpiPen in the office in case your child has an anaplylactic reaction after his vaccines.
Epi Is Readily Available to Treat Most Kids with Anaphylaxis After Vaccines

Still, most probably have never had to.

“Any medication can cause a severe allergic reaction. Such reactions to a vaccine are estimated at about 1 in a million doses, and would happen within a few minutes to a few hours after the vaccination.”

Possible Side-effects from Vaccines

And that’s because anaphylaxis after vaccines is very rare.

Anaphylaxis After Vaccines is Rarely Fatal

And suprisingly, it is even more rare for these cases to be fatal!

“All 30 patients with anaphylaxis survived (9 reports specified anaphylaxis, and we classified another 21 as probable cases, based on compatible clinical features, including respiratory and skin symptoms within 4 hours after vaccination). In half of 22 detailed reports, symptoms developed within 15 minutes after vaccination.”

Wise et al on Postlicensure Safety Surveillance for Varicella Vaccine

But that study just looked at the chicken pox vaccine and used VAERS, so we have to be concerned about under-reporting, right? Well, not necessarily. Under-reporting likely isn’t a big problem for serious reactions.

Anyway, that’s not the only study…

“We identified 33 confirmed vaccine-triggered anaphylaxis cases that occurred after 25,173,965 vaccine doses. The rate of anaphylaxis was 1.31 (95% CI, 0.90-1.84) per million vaccine doses.”

McNeill et al on Risk of anaphylaxis after vaccination in children and adults

The McNeill study used the Vaccine Safety Datalink, which unlike VAERS, is not a passive reporting system. So there is no concern about underreporting.

And like the Wise study, there were no deaths among these vaccine-triggered anaphylaxis cases.

“Fatalities from vaccine-induced anaphylaxis are exceedingly rare.”

Adverse reactions to vaccines practice parameter 2012 update

Similarly, a study in the UK found rare reports of anaphylaxis after vaccines in children and all those children made a full recovery.

Parents should understand that while anaphylaxis is a known side effect to getting a vaccine, it is extremely rare, and can usually be treated. This once again reinforces that vaccines are safe!

More on Anaphylaxis After Vaccines

Did an Islamic Council in Indonesia Issue a Fatwa Against the Measles Vaccine?

A fatwa against a vaccine?

That’s one of those things that can’t be true right?

Did you know that there are Fatwas that support immunizations?
Did you know that there are fatwas that support immunizations?

After all, it was just a few years ago that the Islamic Advisory Group for Polio Eradication met and stated that it “reiterates its trust in the safety and effectiveness of polio and other routine childhood vaccinations as a life-saving tool which protects children; and acknowledge that it fully conforms to Islamic rulings.”

A Fatwa Against the Measles Vaccine

Unfortunately, it’s true.

The Indonesian Ulama Council (MUI), in a Fatwa Commission Meeting on August 20, established that it is illegal (haram) to use vaccines that utilize pigs and their derivatives, including the MR (measles-rubella) vaccine.

Importantly though, they also stated that the use of the MR vaccine is permissible (mubah), because there is no alternative vaccine and measles and rubella are dangerous diseases. So it is still not a good reason to seek a religious exemption to getting vaccinated.

What’s the concern?

Some vaccines use gelatin as a stabilizer. And the gelatin in those vaccines typically comes from pigs.

This isn’t a new issue though.

In 1995, Islamic legal scholars met at a seminar convened by the Islamic Organization for Medical Sciences on the topic The Judicially Prohibited and Impure Substances in Foodstuff and Drugs.

“Transformation which means the conversion of a substance into another substance, different in characteristics, changes substances that are judicially impure or are found in an impure environment, into pure substances, and changes substances that are prohibited into lawful and permissible substances.”

The seminar concluded that “The gelatin formed as a result of the transformation of the bones, skin and tendons of a judicially impure animal is pure…”

So even though Muslims can’t eat pork, they can take medicines packaged in gelatin capsules and they can get vaccines that contain gelatin.

Fortunately, although although some immunization programs ordered a temporary delay when the fatwa was first issued, MR vaccination has resumed in Indonesia. That’s good news, as measles outbreaks are still common in the region.

But why has this become an issue again?

More on the Fatwa Against the Measles Vaccine