Breaking News – The WHO Director has said that there are 7 or 8 top COVID-19 vaccine candidates. (see below)
How’s that COVID-19 vaccine coming along?
Are we getting close to making a vaccine to protect us against SARS-CoV-2 infections?
Or will a coronavirus vaccine be impossible to make???
Like many things, it depends on who you ask…
COVID-19 Vaccine Update
While that probably doesn’t surprise anyone, let’s take a look at what we really do know.
So far 115 COVID-19 vaccines are in development, but only about 10 have entered clinical trials, including:
- mRNA-1273 (Moderna)
- Ad5-nCoV (CanSino Biologicals)
- INO-4800 (Inovio)
- LV-SMENP-DC and pathogen-specific aAPC (Shenzhen Geno-Immune Medical Institute)
- ChAdOx1 nCoV-19 (University of Oxford)
- CoronaVac (Sinovac Biotech)
- 4 different SARS-CoV-2 RNA vaccine candidates (Biontech SE / Pfizer)
- Tableted inactivated vaccine from heat inactivated from COVID-19 patients (Immunitor) – Recruiting
- SARS-CoV-2 inactivated vaccine (Wuhan Institute of Biological Products co., LTD.)
- SARS-CoV-2 inactivated vaccine (Sinopharm)
A few of these have entered Phase II, the next step in vaccine development.
Unfortunately, that means there is still a long way to go!
Even with Operation Warp Speed, the collaboration between the US Dept of Health and Human Services and a number of private firms to accelerate development of 14 vaccine candidates.
And right now, we have no idea how well any of these vaccines will work and what side effects they might cause.
None of that is unexpected at this stage. Remember, even though it is likely hard for most folks to believe, the COVID-19 pandemic is still relatively new.
“We have good candidates now. The top ones are around seven, eight. But we have more than a hundred candidates.”WHO Director-General Tedros Adhanom Ghebreyesus
The other thing that is discouraging is that we are still seeing misinformation about COVID-19…
And misinformation about the COVID-19 vaccines that don’t even exist yet!
“The MenACWY vaccine is being used as an ‘active control’ vaccine in this study, to help us understand participants’ response to ChAdOx1 nCoV-19. The reason for using this vaccine, rather than a saline control, is because we expect to see some minor side effects from the ChAdOx1 nCOV-19 vaccine such as a sore arm, headache and fever. Saline does not cause any of these side effects. If participants were to receive only this vaccine or a saline control, and went on to develop side effects, they would be aware that they had received the new vaccine. It is critical for this study that participants remain blinded to whether or not they have received the vaccine, as, if they knew, this could affect their health behaviour in the community following vaccination, and may lead to a bias in the results of the study.”The Oxford Vaccine Centre COVID-19 Phase I Clinical Trial Explained
On the bright side, we know that once some of these vaccines are developed, manufacturers will be ready to make and distribute them.
Or at least some of them will…
“To bring the disease to an end, we’ll need a safe and effective vaccine. If we do everything right, we could have one in less than 18 months — about the fastest a vaccine has ever been developed. But creating a vaccine is only half the battle. To protect Americans and people around the world, we’ll need to manufacture billions of doses. (Without a vaccine, developing countries are at even greater risk than wealthy ones, because it’s even harder for them to do physical distancing and shutdowns.)
We can start now by building the facilities where these vaccines will be made. Because many of the top candidates are made using unique equipment, we’ll have to build facilities for each of them, knowing that some won’t get used. Private companies can’t take that kind of risk, but the federal government can. It’s a great sign that the administration made deals this week with at least two companies to prepare for vaccine manufacturing. I hope more deals will follow.”Bill Gates: Here’s how to make up for lost time on covid-19
Let’s hope they do, as we will surely need a vaccine if the predictions of future waves of SARS-CoV-2 are true.
More on COVID-19 Vaccines
- About That Mass COVID-19 Vaccination Campaign in Senegal…
- What Has Dr. Fauci Said About a COVID-19 Vaccine?
- What You Need to Know About a COVID-19 Vaccine
- Get All of Your COVID-19 Questions Answered
- The Second COVID-19 Wave Might Not Be COVID-19
- Fauci will oppose any rush to announce COVID-19 vaccine before ‘scientifically sound’
- Scientists were close to a coronavirus vaccine years ago. Then the money dried up.
- WHO – DRAFT landscape of COVID-19 candidate vaccines –20April2020
- CEPI publishes analysis of COVID-19 vaccine development landscape
- UN says 7 or 8 `top’ candidates for a COVID-19 vaccine exist
- COVID-19 vaccine tracker
- Covid-19: do we need more than one vaccine?
- COVID-19 Vaccine Frontrunners
- BARDA’s Rapidly-Expanding COVID-19 Medical Countermeasure Portfolio
- Coronavirus: what have scientists learned about Covid-19 so far?
- The Oxford Vaccine Centre COVID-19 Phase I Clinical Trial Explained
- IVI, INOVIO, and KNIH to partner with CEPI in a Phase I/II clinical trial of INOVIO’s COVID-19 DNA vaccine in South Korea
- WHO – Commitment and call to action: Global collaboration to accelerate new COVID-19 health technologies
- Landmark global collaboration launched to defeat COVID-19 pandemic
- Coronavirus vaccine: when will we have one?
- The Race To Develop A Coronavirus Vaccine
- Bill Gates: Here’s how to make up for lost time on covid-19
- Vaccines are the long-term solution to the pandemic – BBC World News
- Announcing the COVID-19 Therapeutics Accelerator
- WHO – “Immunity passports” in the context of COVID-19
- How will we know whether the coronavirus will come back stronger in the winter?
- When Will Our Coronavirus Vaccine Arrive?
- NWV Fights COVID-19 Misinformation
- Vaccine challenge studies – can it speed up coronavirus vaccine licensing?
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