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Clinical Immunization Safety Assessment (CISA) Project Consultations

Many people think that VAERS is the only way that we can monitor the safety of vaccines in the United States.

In a CISA evaluation, vaccine safety experts from the CDC’s Immunization Safety Office and the CISA academic medical centers meet via scheduled conferences to review complex vaccine safety cases from US healthcare providers.
In a CISA evaluation, vaccine safety experts from the CDC’s Immunization Safety Office and the CISA academic medical centers meet via scheduled conferences to review complex vaccine safety cases from US healthcare providers.

They are clearly unaware of the Vaccine Safety Datalink (VSD) and of the Clinical Immunization Safety Assessment (CISA) Project.

Clinical Immunization Safety Assessment (CISA) Project

CISA is a network of vaccine safety experts that can help health care providers evaluate their patients who may have had a reaction to a vaccine or a suspected vaccine injury.

“CISA is a national network of vaccine safety experts from the CDC’s Immunization Safety Office (ISO), seven medical research centers, and other partners, which provides a comprehensive vaccine safety public health service to the nation.”

Clinical Immunization Safety Assessment (CISA) Project

They can help health care providers and their patients figure out if it it would be safe to get another vaccine, when necessary, after a possible reaction to a previous dose.

CISA experts also do research about vaccine safety.

COVID-19 CISA Clinical Consultation

CISA consults have become particularly important as more and more people have been getting their COVID-19 vaccines.

Remember, our COVID-19 vaccines are rather reactogenic, meaning that they are a little more likely to cause minor side effects, like pain, fever, headache, and fatigue, etc., than many other vaccines.

And they are a little more likely to cause anaphylactic reactions, although at a much lower rate than most people likely think – at a rate of about 2.8 to 5 per million doses.

Combine all of that with some other reactions that have gotten a lot of media attention, like COVID arm, a delayed-injection site reaction, and inflammatory unilateral axillary adenopathy, swollen glands some folks get in their armpit, and you might see why some health care providers might need a little extra help when their patients have a possible reaction.

Fortunately, except for those who have had a severe allergic reaction or an immediate allergic reaction of any severity after a previous dose or known (diagnosed) allergy to a component of the vaccine, which are contraindications to COVID-19 vaccination, most others can be safely vaccinated and protected.

In a CISA COVIDvax consultation, vaccine safety experts can help you get answers to complex COVID-19 vaccine safety questions.
In a CISA COVIDvax consultation, vaccine safety experts can help you get answers to complex COVID-19 vaccine safety questions.

Still, knowing that CISA COVIDvax consults are available if your patient has a reaction and you are unsure if they should get a second dose to complete the series is reassuring.

A CISA COVIDvax consult might also be helpful if you are unsure if your patient has a contraindication before getting their first dose.

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