Tag: meningococcal disease

Complications of Vaccine-Preventable Diseases

We know that vaccine-preventable diseases can be life-threatening.

In the pre-vaccine era, when these diseases were much more common, way too many people died, but still, most people did recover.

They didn’t always survive without complications though.

Tragically, we are starting to see more of these complications as more kids are now getting some of these vaccine-preventable diseases again.

Complications of Vaccine-Preventable Diseases

That we can prevent these serious complications is another benefit of getting vaccinated!

How serious?

Have you ever seen someone who has survived a meningococcal infection?

Do they always have all of their arms and legs?

How about their fingers and toes?

"Baby" Charlotte survived her battle with meningococcemia and continues to take on new challenges!
“Baby” Charlotte survived her battle with meningococcemia and continues to take on new challenges!

There is a reason that we say that you have to earn your natural immunity. You have to survive these diseases to get it. And you want to survive without any long-term complications, which can include:

  1. chicken pox – shingles, secondary bacterial infections, pneumonia, meningitis, encephalitis, seizures, transverse myelitis, Reye syndrome, neonatal varicella, congenital varicella syndrome
  2. congenital rubella syndrome – neonatal death, heart problems, deafness, cataracts, intellectual disability, liver and spleen damage, glaucoma, thyroid problems
  3. diphtheria – myocarditis, heart failure, nerve damage, muscle paralysis
  4. Haemophilus influenzae type b – meningitis, epiglottitis, pneumonia, osteomyelitis, cellulitis, hearing loss, brain damage, loss of limbs
  5. hepatitis A – can rarely lead to liver failure
  6. hepatitis B – chronic hepatitis B, cirrhosis, liver failure, liver cancer
  7. HPV – genital warts, cancer
  8. influenza – parotitis, pneumonia, myocarditis, encephalitis, myositis, rhabdomyolysis, multi-organ failure
  9. measles –pneumonia, seizures, encephalitis, SSPE
  10. mumps – orchitis (inflammation of the testicles), oophoritis (inflammation of the ovaries), pancreatitis, meningitis, encephalitis
  11. pneumococcal disease – pneumonia, mastoiditis, meningitis, bacteremia, sepsis, empyema, pericarditis, hearing loss, brain damage
  12. pertussis – pneumonia, seizures, apnea, encephalopathy, rib fractures
  13. polio – meningitis, paralysis, post-polio syndrome
  14. rabies – it is very rare to survive a rabies infection without treatment
  15. rotavirus – dehydration, intussusception
  16. rubella – arthritis, congenital rubella syndrome
  17. shingles – postherpetic neuralgia, pneumonia, hearing problems, blindness, encephalitis
  18. tetanus – seizures, laryngospasm, fractures, pulmonary embolism, aspiration pneumonia
  19. typhoid fever – intestinal perforation, internal bleeding, peritonitis, hepatitis, osteomyelitis, arthritis, meningitis, myocarditis,
  20. yellow fever – pneumonia, parotitis, sepsis

Anti-vaccine folks rarely talk about the complications of vaccine-preventable diseases. For that matter, they also often push the idea that vaccines don’t even work and that these diseases aren’t even vaccine preventable, don’t they?

Don’t believe them. Vaccines work and they are safe and necessary, especially if you want to avoid these diseases.

More on Complications of Vaccine-Preventable Diseases

Is Meningitis a Side Effect of Vaccines?

Most folks know that there are several meningitis vaccines.

Hib, Prevnar, MMR, and the meningococcal vaccines, for example, all protect folks against meningitis.

Is Meningitis a Side Effect of Vaccines?

So why would some people think that vaccines could actually cause meningitis?

Is meningitis listed on the package insert of any vaccines?
Is meningitis listed on the package insert of any vaccines?

Meningitis is listed as a possible adverse event in the package insert of some vaccines, but only in the section that includes spontaneously reported data from post-marketing experience, where it “may not be possible to reliably estimate their frequency or establish a causal relationship to vaccine exposure.”

It is just like when folks find autism or SIDS in a vaccine’s package insert and think that it is evidence that vaccines are associated with autism or SIDS.

SIDS and autism are listed in Tripedia package insert, but are not causally linked to the vaccine.
SIDS and autism are listed in Tripedia package insert, but are not causally linked to the vaccine.

It isn’t.

These adverse reactions are listed “because of the seriousness OR frequency of reporting.” They are not included because they are serious AND frequent, as some anti-vaccine sites like to proclaim.

How Could a Vaccine Cause Meningitis?

When you think about it, how could a vaccine actually cause someone to develop meningitis?

Why would you even think this is true?

Meningitis is typically caused by a virus, bacteria, parasite, or fungus, etc.

While a live virus vaccine might rarely be able to cause an infection, few of the meningitis vaccines are live virus vaccines. Prevnar, Hib and the meningococcal vaccines are all sub-unit vaccines. Since only a part of bacteria (antigens) is actually present in the vaccine, it is not possible for them to cause an infection.

What about the live virus vaccines, like MMR, chicken pox, and rotavirus?

Since these viral infections rarely cause meningitis, except for mumps, you wouldn’t expect the rare vaccine induced infection to cause meningitis either. A natural measles infection, for example, is more likely to cause encephalitis instead.

“…there is no evidence to link Jeryl Lynn mumps vaccine to aseptic meningitis.”

MMR Package Insert

What about the chicken pox vaccine? There is a case report of a vaccinated child who later developed shingles and meningitis, caused by vaccine strain chicken pox virus. He recovered fully and it is important to note that folks with natural chicken pox are thought to be even more likely to develop shingles, and they too can develop meningitis.

The bottom line is that if someone has meningitis, even if they were recently vaccinated, you shouldn’t be blaming the vaccines.

Like they do with VAERS reports, misusing package inserts is a common method that anti-vaccine folks use to scare parents away from vaccinating and protecting their kids.

What to Know About Meningitis and Vaccine Package Inserts

Although included in some vaccine package inserts, except for rare circumstances with some live virus vaccines, none actually claim that vaccines cause meningitis.

More on Meningitis and Vaccine Package Inserts

How the Anti-Vaccine Movement Takes Advantage of Dead Children and Their Parents

It is bad enough that folks in the anti-vaccine movement use propaganda to scare parents away from vaccinating and protecting their kids.

“The anti-vaccine argument is wrong in both the scientific and moral sense.”
Sarah Kurchak on Here’s How the Anti-Vaccination Movement Hurts Autistic People

Many people also think that the anti-vaccine message is anti-autism.

How the Anti-Vaccine Movement Takes Advantage of Dead Children and Their Parents

But just when you thought that they couldn’t go any lower, folks in the anti-vaccine movement find new ways to demonstrate their lacks of morals.

As a physician, I assure you this story isn’t believable at any level. In my opinion, the “health officials” are conjuring meningitis fairy tales about an “unvaccinated” boogeyman to cover for the much more probable cause of this child’s death: VACCINES.

The much more likely cause is right in front of us: “The child had just received his 4-month-old vaccinations two days beforehand.”

Jim Meehan

What is Dr. Jim Meehan talking about?

A four-month-old who recently died of bacterial meningitis in Chesterfield County, Virginia.

“Notice that THREE of the vaccines given at 4 months are for organisms capable of invading the brain and causing MENINGITIS. Rotavirus is a live virus vaccine capable of shedding from recently vaccinated children. The vaccine pre-clinical trials lacked placebo controls and were associated with infant deaths.

It doesn’t take my medical degree to understand how flimsy are the claims in this story.”

Jim Meehan

While rotavirus is a live virus vaccine, rotavirus rarely causes central nervous system disease. And he died of bacterial meningitis. It shouldn’t take a medical degree to know that rotavirus is a virus, not a bacteria.

While two of the other vaccines routinely given at four months do actually protect you from meningitis, both Prevnar and Hib are sub-unit vaccines, so can’t actually cause disease. Unfortunately, at four months, he would have been only partially protected against Prevnar and Hib, having only received two of four dosages of those vaccines.

“They expect the general public to be ignorant of the fact that we can actually measure the presence of the meningitis causing organisms for which there are vaccines: Haemophilus influenzae, Pneumococcus, and Meningococcus. So, where are the tests that confirm the presence of one of these “vaccine preventable” organisms?! Where’s the spinal tap/CSF pathology report?

As hard as it is for a grieving family to conceive of an autopsy, I pray the family demands a confirmation of the farcical cause of death being contrived in this case.”

Jim Meehan

Has Jim Meehan heard of HIPAA?

Does he read any of the other messages when he is writing his own comments about this family?

Why should this family have to come out and give an explanation for how their child died?
Why should this family have to come out and give an explanation for how their child died?

Is Jim Meehan really a doctor? It shouldn’t take a medical degree to understand that carriers of a disease don’t usually have symptoms of the disease.

“Again, from the article: “Health care officials told Dempsey they BELIEVE an unvaccinated person was carrying meningitis and Killy happened to come into contact with that person.”

They “believe”…give me a break. It should have said, “they made-up a story to cover for the real cause.”

SECOND, people don’t walk around with meningitis. They lay in their beds in a dark room and writhe in pain.

THIRD, the likelihood that an unvaccinated individual was walking around with meningitis is vanishingly small. To even list that in the top 100 options of a differential diagnosis is pure fiction.

FOURTH, where is this hypothetical unvaccinated meningitis shedding “patient zero?” He or she would have been so obviously sick that there is no way new parents would not remember the likely suspect…unless the suspect never existed.”

Jim Meehan

In this case, with a meningococcal infection, which is what the infant is thought to have, about 10% of people are carriers, asymptomatically having the Neisseria meningitidis bacteria in their nose or throat.

In the United States, we have two types of meningococcal vaccines, neither of which is routinely given to infants:

  • Menactra and Menveo – meningococcal conjugate vaccines that protect against serogroups A, C, W, Y and first given when kids are 11 to 12 years old, with a booster at age 16 years.
  • Bexsero and Trumenba – meningococcal conjugate vaccines that only  protect against serogroup B and can be given to kids at increased risk and teens and young adults who want to reduce their risk of getting MenB disease

The only other possibility, since they mentioned that exposed people received antibiotics, would be the Hib bacteria.

“In the prevaccine era, Hib could be isolated from the nasopharynx of 0.5%–3% of normal infants and children but was not common in adults.”

CDC on the Epidemiology and Prevention of Vaccine-Preventable Diseases

Again, these carriers can be contagious, even though they don’t have any symptoms.

“It’s likely that these “health officials” are covering for the pharmaceutical/vaccine industry that pays them so well. It’s “health officials” like this that for decades have pretended that sudden unexplained infant death syndrome (SUIDS), not only has no explanation, but it couldn’t possibly be related to the injection of neurotoxic doses of aluminum into the bodies of tiny baby humans. They can ignore the clustering of infant deaths that occurs around the same times that CDC recommends multiple (5-13) vaccines at one visit, but I won’t.”

Jim Meehan

Why is a family that just lost their child getting harassed by anti-vaccine folks?

This is the modern anti-vaccine movement.
This is the modern anti-vaccine movement.

One clue is that Jim Meehan is pushing the idea that there is a Big Pharma conspiracy behind this child’s death.

An anti-vaccine parenting group helping spread misinformation about this baby's death.
An anti-vaccine parenting group helping spread misinformation about this baby’s death.

And there are many anti-vaccine parenting groups that are helping spread his message around.

Of course, this isn’t the first time this has happened.

Anti-vaccine folks routinely hound parents who die of SIDS and shaken baby syndrome, working to convince them that vaccines caused their deaths.

Even infants who die of vitamin K deficiency bleeding because they skipped their baby’s vitamin K shot all of a sudden have a vaccine injury.

They turn every story of a child’s death or disability into a vaccine injury story.

Shame on them all.

More on the Vultures of the Anti-Vaccine Movement

Why Didn’t Everyone Die with Our 1980s Level of Vaccination Rates?

This is actually a real question that someone recently asked:

“Can someone please explain how we survived the 1980s with vaccination rates well below “herd immunity” thresholds and far fewer vaccines? Why didn’t everyone die?”

J.B. Handley

Mr. Handley even provides a nice chart to give his question some context.

Vaccination rates for 2 year old children in 1985.
The chart shows vaccination rates for 2 year old children in 1985.

So why didn’t everyone die?

That’s easy.

While vaccine-preventable diseases can be life-threatening, they certainly don’t kill everyone who gets them. They are not 100% fatal. Well, rabies usually is, but not surprisingly, rabies wasn’t on his little chart…

Deaths from Vaccine-Preventable Diseases, 1985

What else does Mr. Handley miss?

“Comparisons between rates obtained from immunization records versus the total sample (records and recall) conducted on data collected between 1979 and 1983 showed that the USIS, which accepted parental recall, underestimated the true vaccination rate in preschoolers by as much as 23% for some antigens.”

Simpson et al on Forty years and four surveys: How does our measuring measure up?

The vaccination rates he is citing were based on a phone survey that wasn’t thought to be very accurate, underestimating true vaccination rates. It was last used in 1985.

While vaccination rates weren’t great at the time, they just weren’t as horrible as he makes it seem, but we still had some deaths from vaccine-preventable diseases. Not as bad as the pre-vaccine era though, when hundreds of people died with measles each year.

Here’s the data from the CDC for 1985:

https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/E/reported-cases.pdf

  • 23 deaths from tetanus
  • 4 deaths from pertussis
  • 4 deaths from measles
  • 1 death from rubella
  • 2 cases of congenital rubella syndrome

Unfortunately, it got worse. This was just before the large measles outbreaks from 1989 to 1991, when 123 people died. During those three years, there were also 28 deaths from pertussis, 6 deaths from mumps, 13 deaths from rubella and 77 cases of congenital rubella syndrome!

But then we learned our lesson and we got kids vaccinated. But most of the problems then were about access to vaccines, not parents who intentionally skipped or delayed vaccines for their kids.

Deaths from non-Vaccine-Preventable Diseases, 1985

The CDC Morbidity and Motality Weekly Report includes summaries of notifiable diseases in the United States.Many of the diseases on J.B. Handley’s chart weren’t yet vaccine-preventable in 1985. They were quite deadly though, which is why vaccines were being developed and were eventually added to the schedule to protect our kids from getting them.

But in 1985 (*or in the years before the vaccine was introduced), tragically, the CDC lists:

  • 80 deaths from hepatitis A
  • 490 deaths from hepatitis B
  • 68 deaths from chicken pox
  • 219 deaths from Hib meningitis in children and about another 45 deaths from Hib epiglotittis
  • at least 200 deaths from pneumococcal disease in children*
  • 257 deaths from meningococcal infections
  • 20 to 60 deaths each year from rotavirus infections*

Want us to Turn Back the Clock and go back to an immunization plan (the Jenny McCarthy schedule) that didn’t include vaccines against any of these diseases? We would end up back to when kids still died of meningitis, pneumonia, blood infections, severe dehydration, epiglottitis, and cancer from Hib, pneumococcal disease, rotavirus, hepatitis B, hepatitis A, chicken pox, HPV, and meningococcal disease.

And the answer to Mr. Handley’s question becomes even more obvious.

How did we survive the 1980s with vaccination rates well below “herd immunity” thresholds and far fewer vaccines?

Many people didn’t.

What to Know About Deaths and Vaccination Rates

Poor vaccination rates and fewer vaccines led to more deaths from now vaccine preventable diseases in the mid-1980s.

More on Deaths and Vaccination Rates

 

Meningitis Vaccines

Meningitis is classically defined as an inflammation of the membranes that cover the brain and spinal cord.

Infections that can cause meningitis include:

  • viruses – also called aseptic meningitis, it can be caused by enteroviruses, measles, mumps, and herpes, etc.
  • bacteria – Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes, Haemophilus influenzae type b (Hib), Group B strep
  • a fungus – Cryptococcus, Histoplasma
  • parasites – uncommon
  • amebas – Naegleria fowleri

There are even non-infectious causes of meningitis, including the side-effects of medications and certain systemic illnesses.

Meningitis Vaccines

Teens and young adults need two different kinds of meningococcal vaccines to get full protection.
Teens and young adults need two different kinds of meningococcal vaccines to get full protection.

Fortunately, many of these diseases that cause meningitis are vaccine-preventable.

You don’t often think about them in this way, but all of the following vaccines are available to prevent meningitis, including:

  • Hib – the Haemophilus influenzae type b bacteria was a common cause of meningitis in the pre-vaccine era, in addition to causing epiglottitis and pneumonia
  • Prevnar – you mean it’s not just an ear infection vaccine?
  • MMR – both measles and mumps can cause meningitis
  • Menactra and Menveo – serogroup A, C, W, Y meningococcal vaccines
  • Bexsero and Trumenba – serogroup B meningococcal vaccines

But just because your child has been vaccinated doesn’t mean that you are in the clear if they are exposed to someone with meningitis. They might still need preventative antibiotics if they are exposed to someone with Hib or meningococcal meningitis.

Still, getting fully vaccinated on time is the best way to prevent many of these types of meningitis and other life-threatening diseases.

What to Know About Meningitis Vaccines

Learn which vaccines are available to provide protection against bacterial and viral meningitis.

More on Meningitis Vaccines

What to Do If Your Child Is Exposed to Meningitis

Meningitis is classically defined as an inflammation of the membranes that cover the brain and spinal cord, and it can be caused by:

  • viruses – also called aseptic meningitis, it can be caused by enteroviruses, measles, mumps, and herpes, etc.
  • bacteria – Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes, Haemophilus influenzae type b (Hib), Group B strep
  • a fungus – Cryptococcus, Histoplasma
  • parasites – uncommon
  • amebas – Naegleria fowleri

Surprisingly, there are even non-infectious causes of meningitis. These might be include side-effects of a medication or that the child’s meningitis is a part of another systemic illness.

What to Do If Your Child Is Exposed to Meningitis

While meningitis can be contagious, it greatly depends on the type of meningitis to which they are exposed as to whether or not your child is at any risk.

Teens and young adults need two different kinds of meningococcal vaccines to get full protection.
Teens and young adults need two different kinds of meningococcal vaccines to get full protection.

So while the general advice is to “tell your doctor if you think you have been exposed to someone with meningitis,” you should try and gather as much information as you can about the exposure.

This information will hopefully include the type of meningitis they were exposed to, specifically if it was bacterial or viral, the exact organism if it has been identified, and how close of an exposure it was – were they simply in the same school or actually sitting next to each other in the same room.

For example, while the CDC states that “people who are close contacts of a person with meningococcal or Haemophilus influenzae type b (Hib) meningitis are at increased risk of getting infected and may need preventive antibiotics,” they also state that “close contacts of a person with meningitis caused by other bacteria, such as Streptococcus pneumoniae, do not need antibiotics.”

And you often don’t need to take any preventive measures if you are exposed to someone with viral meningitis.

While that might sound scary, it is basically because you typically aren’t at big risk after this kind of exposure. You could get the same virus, but the chances that it would spread and also cause meningitis are very unlikely.

Not only does Viera Scheibner think that vaccines cause SIDS and shaken baby syndrome, she thinks they are contaminated with amoeba.
The Naegleria fowleri ameba that can cause meningitis can be found in warm freshwater, including lakes and rivers.

Other types of meningitis, like primary amebic meningoencephalitis (PAM) and fungal and parasitic meningitis aren’t even contagious.

The Histoplasma fungus spreads from bird or bat droppings, for example, not from one person to another.

And parasites typically spread from ingesting raw or undercooked food, or in the case of Baylisascaris procyonis, from ingesting something contaminated with infectious parasite eggs in raccoon feces.

What to Do If Your Unvaccinated Child Is Exposed to Meningitis

Vaccines can prevent a number of different types of meningitis.

From Hib and Prevnar to MMR and the meningococcal vaccines, our children routinely get several vaccines to prevent meningitis.

While these meningitis vaccines don’t protect us from all of the different types of viruses, bacteria, and other organisms that can cause meningitis, they do prevent many of the most common.

So what do you do if your unvaccinated child is exposed to meningitis?

You should immediately call your pediatrician or local healthy department, because they might need:

  • antibiotics (usually rifampin, ciprofloxacin, or ceftriaxone) if the meningitis was caused by Neisseria meningitidis
  • antibiotics (rifampin) if the meningitis was caused by Haemophilus influenzae type b (Hib)

The availability of these antibiotics isn’t a good reason to skip or delay getting vaccinated though, as you won’t always know when your kids have been exposed to meningitis and not all types of vaccine-preventable meningitis can be prevented with antibiotics.

Of course, getting fully vaccinated on time is the best way to prevent many of these types of meningitis and other life-threatening diseases.

What to Do If Your Vaccinated Child Is Exposed to Meningitis

Even if your child is vaccinated, they might still need preventative antibiotics if they are exposed to someone with Hib or meningococcal meningitis, as vaccines are not 100% effective.

“Regardless of immunization status, close contacts of all people with invasive meningococcal disease , whether endemic or in an outbreak situation, are at high risk of infection and should receive chemoprophylaxis.”

AAP Red Book on Meningococcal Infections

This is especially true if they are not fully vaccinated.

Remember, to be fully vaccinated against Haemophilus influenzae type b, kids get a 2 or 3 dose primary series of the Hib vaccine when they are infants and a booster dose once they are 12 months old.

In the case of exposure to Hib meningitis, antibiotic prophylaxis would be recommended if:

  • the child is fully vaccinated, but there is a young child, under age 4 years, in the house who is unvaccinated or only partially vaccinated
  • the child is fully vaccinated, but there is another child in the house who is immunocompromised
  • the child is only partially vaccinated and under age 4 years
  • there is an outbreak in a preschool or daycare, with 2 or more cases within 60 days

And anyone exposed to someone with meningococcal meningitis should likely get antibiotics (chemoprophylaxis), even if they are fully vaccinated.

Talk to your pediatrician or local health department if your child is exposed to meningitis and you aren’t sure what to do, whether or not your child has been vaccinated.

What to Know About Getting Exposed to Meningitis

Learn what to do if your child is exposed to someone with meningitis, especially if they are unvaccinated, or have been exposed to someone with Hib meningitis or meningococcal disease.

More on Getting Exposed to Meningitis

Meningococcal Disease Outbreaks

Meningitis B vaccination poster during an outbreak at Princeton.There are two types of meningococcal vaccines that can help prevent meningococcal disease, including:

  • Menactra and Menveo – meningococcal conjugate vaccines that protect against serogroups A, C, W, Y
  • Bexsero and Trumenba – meningococcal conjugate vaccines that only  protect against serogroup B

And while children routinely get their first dose of either Menactra or Menveo when they are 11 to 12 years old and a booster at age 16 years, the MenB vaccines only have a “permissive” recommendation.

That means that there isn’t a formal recommendation that all kids get Bexsero or Trumenba. Instead, older teens and young adults between the ages of 16 and 23 years can get vaccinated if they want to protect themselves from most strains of serogroup B meningococcal disease.

Meningococcal Disease Outbreaks

Although the CDC reports that the incidence of menB disease is low, there have been at least ten outbreaks of menB disease on college campuses since 2013, including:

  • University of California, Santa Barbara four cases – one student had both his feet amputated (2013)
  • Princeton University – nine cases  and one death – a student at Drexel University (2013-14)
  • Providence College – two cases (2015)
  • University of Oregon – seven cases and one death (2016)
  • Santa Clara University – three cases (2016)
  • Rutgers University- New Brunswick – two cases (2016)
  • University of Wisconsin-Madison – three cases (2016)
  • Oregon State University – six cases (2017)
  • University of Massachusetts Amherst – two cases (2017)

The latest outbreak is at Colgate University. One students has been diagnosed with meningococcal meningitis disease and the school “will be offering vaccination clinics for all students who have not already received two doses of the serogroup B immunization.”

What to Know About Meningococcal Disease Outbreaks

Meningococcal disease is not common, but the effects of this vaccine-preventable disease disease can be devastating, which is why experts work to quickly get outbreaks under control.

More on Meningococcal Disease Outbreaks

Updated on April 7, 2018