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Show Me The Insert – PNH Medications Edition

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Vaccination is essential for patients with paroxysmal nocturnal hemoglobinuria (PNH) prior to receiving treatments like eculizumab and iptacocan, as these medications increase the risk of vaccine-preventable diseases. Specifically, meningococcal vaccines are mandated due to the heightened risk of meningococcal disease in individuals receiving complement inhibitor therapy.

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A Woman With Paroxysmal Nocturnal Hemoglobinuria Becomes the Latest Vaccine Injury Story

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The story of Alexis Lorenze highlights misinformation about vaccine injuries, as anti-vaccine advocates incorrectly link her worsening paroxysmal nocturnal hemoglobinuria (PNH) to vaccinations. In reality, her condition can be exacerbated by infections like parvovirus B19, emphasizing the importance of vaccines for those at high risk like her to prevent severe complications.

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