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Show Me The Insert – PNH Medications Edition

Vaccination is essential for patients with paroxysmal nocturnal hemoglobinuria (PNH) prior to receiving treatments like eculizumab and iptacocan, as these medications increase the risk of vaccine-preventable diseases. Specifically, meningococcal vaccines are mandated due to the heightened risk of meningococcal disease in individuals receiving complement inhibitor therapy.

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A Woman With Paroxysmal Nocturnal Hemoglobinuria Becomes the Latest Vaccine Injury Story

The story of Alexis Lorenze highlights misinformation about vaccine injuries, as anti-vaccine advocates incorrectly link her worsening paroxysmal nocturnal hemoglobinuria (PNH) to vaccinations. In reality, her condition can be exacerbated by infections like parvovirus B19, emphasizing the importance of vaccines for those at high risk like her to prevent severe complications.

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Another Chart That Shows Vaccines Work

The MenC vaccine was introduced in the UK in 1999, leading to sustained declines in MenC disease. Anti-vaccine influencers misusing mortality graphs to claim vaccines don’t work are easily debunked by data showing the drop in meningococcal disease rates with vaccine introductions. The MenACWY vaccination program also showed a herd protection effect.

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Some Vaccines Don’t Stop Infection and Transmission of Disease

Some vaccines don’t prevent infection and transmission of disease. While this might seem concerning, these vaccines still effectively prevent the disease in the vaccinated person and can reduce the spread of diseases. Understanding the difference between infection and disease is crucial in recognizing the impact of vaccines. Vaccination remains essential for protecting individuals and preventing disease transmission.

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