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When Infants Spit Up Their Rotavirus Vaccine…

As most folks know, the rotavirus vaccine is an oral vaccine that is given to infants at two, four, and sometimes six months.

While many parents and pediatricians appreciate that it isn’t another shot, we are giving an oral vaccine to kids at a time when many of them still spit up a lot!

Infants are less likely to spit up their dose of rotavirus vaccine if it is directed toward the side of their cheek. Photo by Vincent Iannelli, MD
Infants are less likely to spit up their dose of rotavirus vaccine if it is directed toward the side of their cheek. Photo by Vincent Iannelli, MD

So what happens if they spit up after they get their dose?

When Infants Spit Up Their Rotavirus Vaccine…

The first thing you can do is try to help prevent them from spitting up the dose in the first place!

How do you do that?

It can help to give the dose of rotavirus vaccine before you give the infant their shots and then be sure to direct the dose towards the infant’s cheek and not simply towards the back of their mouth, which might gag them.

And if they still spit up?

“If for any reason an incomplete dose is administered (e.g., infant spits or regurgitates the vaccine), a replacement dose is not recommended, since such dosing was not studied in the clinical trials. The infant should continue to receive any remaining doses in the recommended series.”

RotaTeq Prescribing Information

Then you don’t repeat the dose.

Why not?

“The practitioner should not readminister a dose of rotavirus vaccine to an infant who regurgitates, spits out, or vomits during or after administration of vaccine. No data exist on the benefits or risks associated with readministering a dose. The infant should receive the remaining recommended doses of rotavirus vaccine following the routine schedule (with a 4-week minimum interval between doses).”

Prevention of Rotavirus Gastroenteritis Among Infants and Children Recommendations of the Advisory Committee on Immunization Practices (ACIP)

Mostly because it hasn’t been studied, but also, it just isn’t practical. After all, how would you know how much of the vaccine was spit up? How much was swallowed and made it to the child’s small intestine where it can induce immunity.

Fortunately, few infants actually spit up their dose of rotavirus vaccine and the vaccine has been so effective, we don’t see very much rotavirus these days. So even if these infants who spit up one of their doses weren’t fully protected, as long as everyone else around them is vaccinated and protected, they can safely hide in the herd!

What about the rotavirus vaccine that was spit up?

“There are no case reports in the literature of health care providers contracting rotavirus during the process of administering the vaccine.”

Rotavirus Vaccine: Questions and Answers for Health Care Providers

Even though it is an attenuated virus in the vaccine, the spit up should be carefully washed up and everyone who was possibly exposed should carefully wash their hands.

More on Rotavirus Vaccines

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