Tag: mutations

Wakefield’s Mutating Measles and Natural Herd Immunity

Andrew Wakefield is back and warning folks about “mutant measles” and our loss of natural herd immunity.

Andrew Wakefield and Del Bigtree talk about mutating measles and natural herd immunity.

Of course, that isn’t what is causing our record breaking measles outbreaks.

Natural Herd Immunity

Why is he talking about measles this time, besides a new propaganda film he is already pushing?

“We are in a time now when obviously anti-vaxxers are getting blamed for these measles outbreaks here in this country – the biggest measles outbreak since they declared measles to be eradicated from America. But what you had to say was really interesting. First, the only deaths I’ve seen really specifically have been the stewardess in Israel. We hear about she died. She got the measles but she was vaccinated. There was a child, a young man in Europe. He died after having measles. He was vaccinated… What’s happening? Why is the news not talking about how these were vaccinated individuals? What’s happening with measles?”

Del Bigtree on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

He is looking to play the blame game. Measles cases are on the rise and while they aren’t all due to vaccine hesitancy, many are. And that has left anti-vaccine folks looking to shift the blame elsewhere.

And with cases on the rise, we are also seeing measles deaths on the rise. Which has to make you think, has Del Bigtree really only heard of two measles deaths? After all, there have been over a hundred in Europe, including eight measles deaths in Italy alone.

“I guess the question comes down to that poor air stewardess. Did she die because she was vaccinated? That’s a really big question.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Is that really even a question?

A 43-year-old mother of three, died four months after getting measles while working as a flight attendant for El Al, getting exposed on a flight from New York and Israel.

She died because someone exposed her to measles, a life-threatening disease.

“It really is a question of who is to blame, who’s really to blame for the resurgence of measles around the world. Is it those they label anti-vaxxers or is it in fact those responsible for vaccination?”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Hmm, who’s to blame for the outbreaks. Anti-vaxxers or those vaccinating and protecting folks…

Guess who Wakefield is blaming?

“I’ve been studying measles since 1990. It’s something I know something about. As I got into it… I suddenly realized what the problem was and I also realized that they, on the other side, the vaccinologists, the industry, the smart ones, know it. And it’s their greatest fear.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

So what did Wakefield figure out?

This is the consequence of better hygiene, sanitation, and nutrition in the first part of the century and vaccines later on.
This is the consequence of better hygiene, sanitation, and nutrition in the first part of the century and vaccines later on.

He talks about natural herd immunity, shows mortality graphs, and goes on about how measles is most serious in those under one and adults, but is a “trivial disease” in children.

“Nature has constrained the age of exposure to the majority of people getting measles when they are children, because that’s when they can get it safely.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

So by vaccinating people, he argues that we have interrupted the protection you get from natural infections. Adults don’t have lifetime immunity from their childhood infections and infants don’t have the passive immunity they get from their mothers, protecting them when they are most at risk.

He goes so far as to say that measles deaths would have “declined to zero” if we had never vaccinated!

What’s the problem with his theory?

Typical mortality graphs that anti-vax folks use don't tell the whole story...
Typical mortality graphs that anti-vax folks use don’t tell the whole story…

Well, for one thing, why didn’t natural herd immunity protect folks from dying with measles in the early 1900s? Or in the 1950s, when we still had 400 deaths a year in the United States?

Why didn’t natural herd immunity get rid of smallpox or any other disease?

And if we go back to the pre-vaccine era, when everyone got measles, what happens to all those with immune system problems who will almost certainly die if they get exposed to measles? These are the people who rely on herd immunity now, but they will be at big risk in this natural herd immunity model, because it means that millions of kids get measles every year.

Give Another Dose…

What do Wakefield and Del think that our answer will be to the measles outbreaks?

“The only answer they have is to give another dose, and give another dose, and give another dose.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Of course, there are no calls to give “one more in college” and “two more MMR in adulthood” for measles protection as Del Bigtree claims.

In fact, two doses are very effective protection against measles.

“We report a screen of plasma donors confirming that widespread use of childhood measles vaccination since 1963 resulted in a decrease in average measles virus antibody titers among plasma donors, which is reflected in intravenous immunoglobulins (IVIGs).”

Modrof et al on Measles Virus Neutralizing Antibodies in Intravenous Immunoglobulins: Is an Increase by Revaccination of Plasma Donors Possible?

And no, the paper Wakefield talked about doesn’t prove that the MMR vaccine doesn’t work.

“With the success of the measles vaccination program and the ongoing World Health Organization efforts to eliminate and ultimately eradicate measles worldwide, a replacement of the measles virus antibody titer as a functional potency requirement for IVIG seems inevitable in the long term.”

Modrof et al on Measles Virus Neutralizing Antibodies in Intravenous Immunoglobulins: Is an Increase by Revaccination of Plasma Donors Possible?

The article actually talks about how successful the MMR vaccine is and just says that folks who are vaccinated don’t get the extra high levels of antibodies needed to make IVIG, which is used to treat people who are exposed to measles.

That doesn’t mean their vaccine didn’t work though. Many studies have demonstrated an amnestic response after measles vaccination, meaning that antibodies levels rise with any exposure to wild measles virus.

Mutating Measles

Little that Andrew Wakefield or Del Bigtree say in their video on mutating measles is true.

When he finally gets to actually talking about mutating measles, it is about a paper describing a new D4 subgenotype of measles.

Most measles outbreaks are now caused by B3 and D8 measles strains.
Most measles outbreaks are now caused by B3 and D8 measles strains.

A strain for which antigenic shift might have led to resistance to vaccine induced protection, but fortunately, one that is rarely found.

And it isn’t what’s causing our measles outbreaks.

Remember, most people who get measles are unvaccinated.

“It’s that certainty that makes them so dangerous.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Why is Wakefield so certain he is right?

“This is why, when that air hostess, got her vaccine, which she was probably promised, her mother was promised that it would give her protection for life, and it didn’t. She was susceptible again as an adult when it was more serious. So measles vaccination had made what was increasingly a trivial disease in children a much, much more dangerous disease. So who’s responsible for the resurgence of measles? Who’s responsible for the death of that girl?

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Who does he blame for bringing measles back?

Wakefield blames the vaccinologists…

Who's really to blame for low immunization rates and continuing outbreaks?
Who’s really to blame for low immunization rates and continuing outbreaks?

How many people still blame Wakefield?

“So the adult population of this country is completely unprotected from measles virus unless you have had a natural infection. Boosting it with vaccination is not going to make any difference and that is an incredibly worrying situation.”

Andrew Wakefield on WAKEFIELD’S WARNING: “MEASLES IS MUTATING”

Just remember, the measles vaccine is very effective, especially when you get two doses. Most of the people who are getting measles are unvaccinated, either intentionally or because of lack of access.

And measles is hardly a trivial disease.

Neither is listening to this kind of anti-vaccine propaganda.

More on Mutating Measles and Natural Herd Immunity

Who Is Larry Palevsky?

Think you know all of the anti-vaccine pediatricians?

“The pediatrician who spoke on Monday night, Dr. Lawrence Palevsky, is regularly cited in pamphlets circulated in New York City that urge women not to get their children vaccinated. His views have no basis in science, experts said.”

Despite Measles Warnings, Anti-Vaccine Rally Draws Hundreds of Ultra-Orthodox Jews

Sadly, there is more than one pediatrician pandering to parent’s fears about vaccines these days.

Who Is Larry Palevsky?

Although not as well known as Sears or Thomas, who were thrown into the spotlight because they wrote anti-vaccine books and were associated with measles outbreaks in their areas, it would be hard to say what makes Palevsky different from any other anti-vaccine expert.

A holistic pediatrician, he was an “expert” for the anti-vaccination movie The Greater Good. Palevsky also often links to and quotes other notorious anti-vax “experts.”

He even appeared on the Gary Null Show – in addition to being anti-vax, Gary Null is among the alternative medicine folks who actually denies that HIV causes AIDS.

So no one should be surprised that Palevsky spoke at an anti-vaccine rally during the longest measles outbreak we have had in the United States in over 25 years. An ongoing measles outbreak that health officials are still struggling to contain.

At the rally, he talked at length about mutating viruses and falsely claimed that failed vaccines were producing a new strain of measles. Women scribbled into notepads as he spoke. Others filmed his comments, sending them to their contacts on WhatsApp. Essentially, he said, there were no studies available to show how the vaccine affects the human body.

“Is it possible that the measles-mumps-rubella vaccine that is somehow being given in this lot to communities in Williamsburg and Lakewood and Monsey, maybe in Borough Park, is it possible that these lots are bad?” he asked, referring to areas in New York and New Jersey with large ultra-Orthodox Jewish communities.

“It’s fascinating because we’re told how contagious the disease is, but somehow it’s centered in the Jewish community.”

Despite Measles Warnings, Anti-Vaccine Rally Draws Hundreds of Ultra-Orthodox Jews

It’s fascinating that a pediatrician would actually think that any of this is possible

Bad lots of vaccines?

Does Palevsky, who runs a Wellness Center, realize that only about 3-4% of the people who have gotten measles in Brooklyn and Rockland County have been fully vaccinated. Most are unvaccinated.

How does that fit into Palevsky’s theories about bad lots, mutating measles viruses, and failed vaccines?

Since Palevsky doesn’t seem to believe in the germ theory of disease, that viruses and bacteria can actually cause us to get sick, it isn’t hard to figure out. For him, of course, it would be easier to blame vaccines instead of the measles virus, I guess even vaccines that these folks have never received.

Sure. It is anything and everything except the fact that parents are intentionally not vaccinating and protecting their kids…

What’s really fascinating is that people are still listening to this kind of misinformation when they can see the consequences of what happens when they leave their community unvaccinated and unprotected.

“I believe in what’s called a starvation diet for kids when they’re sick.”

Larry Palevsky

And that they are listening to it from folks like Palevsky!

“Most of the reason that kids get sick is to move or get rid of wastes anyway.”

Larry Palevsky

But just in case they don’t get better by just removing the wastes in their body or by using supplements, essential oils or herbs and reducing their stress levels, Palevsky is very happy to refer your child to one of the homeopaths, acupuncturists, chiropractors and/or other health professionals in his office.

Palevsky wants your child to “breathe more” when they get sick…

And that’s a clue to why we continue to see outbreaks of measles.

This industry of holistic and integrative “health professionals” goes out of their way to make sure parents are too scared to vaccinate their kids.

More on Larry Palevsky

Can You Prove That Jamie McGuire Books Don’t Make Teens Do Drugs?

Apparently, Jamie McGuire is a best-selling author.

According to Yahoo Lifestyle, she is the “author of 20 books in the New Adult genre (for ages 18-30), including Walking Disaster — which debuted at No. 1 on the New York Times, USA Today and Wall Street Journal bestseller lists — as well as the apocalyptic thriller Red Hill.”

And she wants everyone to know that she does not consent!

Can You Prove That Jamie McGuire Books Don’t Make Teens Do Drugs?

What does Jamie McGuire not consent to?

Since her whole post is about proving this and that about vaccines, which she seems to think are bad, I am guessing that she does not consent to getting vaccinated or to vaccinating her kids.

The thing is though, no one is trying to force her to vaccinate her kids.

You can just say that you don’t want to vaccinate your kids, coming out as another anti-vaccine pseudo-celebrity, without hijacking “I do not consent” messaging.

Anyway, her concerns about vaccines have been addressed. Indeed, they have been talked about a million times. If she were truly aware, she would stop being misled by anti-vaccine arguments that scare parents away from thinking that vaccines are safe, with few risks, and necessary.

Do we have proof? We have evidence!

And as the title says, can you prove that her books don’t make teens do drugs?

More on Jame McGuire and Consent

Do Vaccines Cause Mastocytosis?

Children with mastocytosis have extra mast cells, a normal type of cell that we all have that release histamine and other chemicals when activated.

As you can imagine, having too many mast cells, which release too much histamine, isn’t a good thing.

What Causes Mastocytosis?

Mastocytosis, some forms of which have been known since 1869, is caused by spontaneous mutations that aren’t passed on to future generations (somatic mutations).

“Most forms of mastocytosis are caused by a mutation of the KIT gene on the 4q12 chromosome – a mutation that increases cellular reproduction. The c-KIT gene mutation creates an overgrowth of one cell line of mast cells.”

What is mastocytosis?

And the symptoms you have with mastocytosis depends on the type you have, which can include localized (solitary, maculopapular cutaneous, diffuse cutaneous) vs systemic mastocytosis.

“The severity of the symptoms associated with mastocytosis may vary from mild to life-threatening. In general, symptoms occurring in mastocytosis are mainly due to the release of chemicals from the mast cells and thus produce symptoms associated with an allergic reaction.”

Mastocytosis – Rare Disease Database

Localized mastocytosis is usually present at birth or early infancy.

Do Vaccines Cause Mastocytosis?

Since it is caused by spontaneous mutations and is often present at birth or early infancy, there is no reason to think that vaccines could cause mastocytosis.

Vaccines and Mastocytosis

That’s not to say that you shouldn’t think about vaccines if your child has mastocytosis.

Although almost anything can be a trigger for kids with mastocytosis, from insect stings, skin rubbing, antibiotics, aspirin, cough medications, exposure to heat or cold, and stress, there have been a few reports of vaccines being a trigger.

“In childhood, the risk for anaphylactic episodes was limited to children with extensive skin disease, but nonexistent for children with mastocytoma or limited macular lesions. This is in good agreement with the literature, where children with anaphylaxis were described as having clinically severe skin involvement of mastocytosis, although the levels of skin involvement were not given and tryptase concentrations not determined. Children with fatal anaphylaxis, described in three case reports, all had suffered from extensive blistering skin disease…”

Brockow et al on Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients.

It is important to note that these are kids with severe disease though and not the more typical type of localized disease that the average child will have.

An infant with diffuse cutaneous mastocytosis. Lange et al. (CC BY-NC 3.0)
An infant with diffuse cutaneous mastocytosis. Lange et al. (CC BY-NC 3.0)

It should also be noted that viral and bacterial infections with fever, some of which are vaccine preventable, can also be a trigger.

Still, if your child has extensive skin disease, your specialist will likely talk about premedication before vaccines and watching your child closely afterward in case they have an anaphylactic reaction.

Should they get fewer vaccines at a time?

Surprisingly, it depends on who you ask, but it should be noted that all of the discussions about vaccines are for kids with diffuse cutaneous mastocytosis (DCM), a rare form of cutaneous mastocytosis.

“Although patients with mastocytosis can be vaccinated according to the standard schedule, precautions to prevent MC activation and degranulation have been formulated by experts, particularly in cases of diffuse skin manifestations”

And none say to skip vaccines, although some say to use an alternative immunization schedule, getting one vaccine at a time perhaps, especially for the initial doses.

It should be clear that kids with mastocytosis can and should be vaccinated though and vaccines do not actually cause mastocytosis.

More on Vaccines and Mastocytosis