Why Was My Titer Negative After My Chicken Pox Vaccine?

Having a negative titer after a vaccine might confuse some folks, as a vaccine should lead to immunity and a positive titer test.

Why Was My Titer Negative After My Chicken Pox Vaccine?

In the case of chicken pox, some folks will simply be confused about why you had a titer checked in the first place.

“There are currently no commercially available VZV IgG methods sensitive and specific enough to reliably detect seroconversion to vaccine.”

Chicken Pox – Interpreting Laboratory Tests

A chicken pox titer can help to confirm that you had a natural chicken pox infection, but it won’t confirm that someone has had the vaccine or that they have immunity after being vaccinated.

“In what circumstances should I obtain a varicella titer after vaccination?

Postvaccination serologic testing is not recommended in any group, including healthcare personnel.”

Ask the Experts About Chicken Pox

To satisfy school or work requirements, people should usually either have:

  • documentation of two doses of the chicken pox vaccine, or
  • titers to confirm that they have had a natural chicken pox infection

What if your titer is negative after a natural chicken pox infection?

Then you will likely have to get vaccinated.

If you have never been vaccinated or had a natural chicken pox infection with evidence of immunity, then you should get two doses of the chicken pox vaccine.
If you have never been vaccinated or had a natural chicken pox infection with evidence of immunity, then you should get two doses of the chicken pox vaccine.

You likely shouldn’t be required to have a titer done after you have had your chicken pox vaccines though.

More on Understanding Chicken Pox Titer Tests

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