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Beware of Folks Pushing the Idea That COVID-19 Vaccine Trials Will Fail from the Start

That multiple COVID-19 vaccines might soon be found safe and effective and ready to be distributed to millions of people seems to have rattled more than a few people. That must be why we are starting to see some of these folks pushing the idea that these vaccines trials have already failed, even though they haven’t even finished yet.

What's the one question you need to know about Peter Doshi?
What’s the one question you need to know about Peter Doshi?

But why do they want the COVID-19 trials to fail?

Beware of Folks Pushing the Idea That COVID-19 Vaccine Trials Will Fail from the Start

Or maybe a better question might be why do they want you to think we won’t have safe and effective COVID-19 vaccines?

“When a vaccine comes into usage, we might therefore not know if it has any important effects. We should not be too optimistic about what a corona vaccine might accomplish if we compare with the influenza vaccines, which do not have documented effects on transmission, hospital admission, serious disease or death. We will know very little about the harms of the vaccine, and nothing about the rare but serious harms.”

Peter C Gøtzsche on The coronavirus pandemic: can we handle such epidemics better?

Why do they want you to think they will fail?

“But the protocols should heighten anxiety rather than alleviate it. A close reading suggests the clinical trials have been designed to ensure the greatest possible success for these candidates — and that could overstate their effectiveness.”

William Haseltine on Beware of covid-19 vaccine trials designed to succeed from the start

Their main concern?

They don’t think that the initial COVID-19 vaccine trials can prove that the vaccines can prevent severe disease.

Natalie Dean explains why the current COVID-19 trails were set up the way they were and why they are using acceptable endpoints.
Natalie Dean explains why the current COVID-19 trails were set up the way they were and why they are using acceptable endpoints.

Should that be a concern right now?

“The justification of a mild, more common, endpoint as the primary endpoint in vaccine trials would be predicated on the assumption that the benefit of the vaccine on the selected endpoint is reasonably likely to predict clinical benefit for cases of microcephaly or other severe complications.”

Considerations for the design of vaccine efficacy trials during public health emergencies

Maybe not, when you consider that it takes longer to do trials that focus on severe cases.

“Study endpoints should be selected to support the broader intended use of a vaccine and should reflect the public health burden of interest.”

Considerations for the design of vaccine efficacy trials during public health emergencies

But if a COVID-19 vaccine is shown to be safe and effective at preventing “any occurrence of covid-19, not necessarily a severe case,” should we wait until it is shown to also prevent severe cases as the death count continues to rise?

“Typically, the more severe a disease is, the better chance a vaccine has of preventing that disease. So, a vaccine that’s 50% effective against mild COVID disease—which might be the endpoint that’s measured in a clinical trial, or any evidence of COVID infection with any symptom, which is how a lot of trials are designed—might be more effective against severe disease.”

A Top Vaccine Expert Answers Important Questions About a COVID-19 Vaccine

That doesn’t mean we want a rushed vaccine that isn’t safe or that doesn’t work, but we do want things to move along much faster than they usually do.

We need a safe and effective COVID-19 vaccine now.

“The second characteristic of denial is the use of fake experts. These are often credentialed individuals who hold views outside the broader scientific consensus.”

Believers need to be as prepared for a Covid-19 vaccine as anti-vaxxers are against it

We don’t need folks like Peter Doshi and Peter C Gøtzsche and others, who have been critical of other vaccines (shouldn’t they have mentioned that in their articles???), scaring everyone about COVID-19 vaccines that haven’t even been approved yet.

More on the COVID-19 Vaccine Trials

Last Updated on April 6, 2024

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